X-ray induced alterations in the differentiation and mineralization potential of murine preosteoblastic cells

To evaluate the effects of ionizing radiation (IR) on murine preosteoblastic cell differentiation, we directed OCT-1 cells to the osteoblastic lineage by treatment with a combination of β-glycerophosphate (β-GP), ascorbic acid (AA), and dexamethasone (Dex). In vitro mineralization was evaluated based on histochemical staining and quantification of the hydroxyapatite content of the extracellular bone matrix. Expression of mRNA encoding Runx2, transforming growth factor β1 (TGF-β1), osteocalcin (OCN), and p21^CDKN1A was analyzed. Exposure to IR reduced the growth rate and diminished cell survival of OCT-1 cells under standard conditions. Notably, calcium content analysis revealed that deposition of mineralized matrix increased significantly under osteogenic conditions after X-ray exposure in a time-dependent manner. In this study, higher radiation doses exert significant overall effects on TGF-β1, OCN, and p21^CDKN1A gene expression, suggesting that gene expression following X-ray treatment is affected in a dose-dependent manner. Additionally, we verified that Runx2 was suppressed within 24 h after irradiation at 2 and 4 Gy. Although further studies are required to verify the molecular mechanism, our observations strongly suggest that treatment with IR markedly alters the differentiation and mineralization process of preosteoblastic cells.     

Satellite and ground detection of very dense smoke clouds produced on the islands of the Paraná river delta that affected a large region in Central Argentina

Intense fires were produced on the Paraná river delta islands, Argentina, during most part of 2008, by a combination of an exceptionally dry period and the farmers’ use of a fire land-cleaning technique. In April 2008, those fires significantly affected the nearby regions and their inhabitants, from Rosario city to Buenos Aires mega-city. In this work we present satellite as well as ground Aerosol Optical Depth (AOD) at 550 nm data obtained during the propagation of pollution clouds to the central zone of Argentina. The highest value (1.18) was registered at Buenos Aires by atmospheric remote sensing, using the satellite instrument MODIS/Terra on April 18th 2008 at 10:35 local time (= UT − 3 h). On the same day, ground air quality detectors also measured in this city the highest Total Suspended Particle (TSP) value of the month, 2.02 mg/m³. The AOD(550) daily variation at Rosario Astronomical Observatory, which is located near the Paraná riverside, was derived by combining solar ultraviolet erythemal irradiance data (measured with a YES biometre) with model calculations. On April 25th 2008, from 12:00 to 15:30 local time, a rather high and constant AOD(550) value was registered, with a mean value of (0.90 ± 0.21). Cities located on the side of the Rosario–Buenos Aires highway (San Nicolás, Baradero and San Pedro) were also affected, showing a mean AOD(550) between the Rosario and Buenos Aires values. The particulate matter was collected with gridded samplers placed on the Paraná river islands as well as at the Rosario Observatory. They were analysed with a Scanning Electron Microscope (SEM) and mainly showed a biological origin. Even if normally large particles travel small distances from the source, organic aerosol in the range of 40–100 μm and complex asymmetric structures were registered several kilometres away from the aerosol sources on the islands. Another event of intense UV index attenuation (98.6%) occurred on September 18th 2008, due to very dense smoke clouds that extended over the Rosario area for several hours. The clouds were driven away from the fires by East–northeast and East–southeast winds. The minimum value of this index measured around noon allows to derive a maximum AOD(550)_max = (3.65 ± 0.90) at 12:45 local time. Soot clouds extended over the Paraná river, transporting Burned Biomass Debris (BBD) that deposited on Rosario. In particular, burned leaves and small branches with dimensions of 1–20 cm were collected. The mean (BBD) particles deposited on the ground from 7:00 to 19:00 local time were (0.92 ± 0.20) BBD/(m² h).     

Solar cycle and latitude dependence of high-beta suprathermal plasma conditions in interplanetary space between 1.3 and 5.4 AU

The analysis of energetic particles and magnetic field measurements from the Ulysses spacecraft has shown that in a series of events, the energy density contained in the suprathermal tail particle distribution is comparable to or larger than that of the magnetic field, creating conditions of high-beta plasma. In this work we analyze periods of high-beta suprathermal plasma occurrences (β_ep > 1) in interplanetary space, using the ratio (β_ep) of the energetic particle (20 keV to ∼5 MeV) and magnetic field energy densities from measurements covering the entire Ulysses mission lifetime (1990–2009) in order to reveal new or to reconfirm some recently defined interesting characteristics. The main key-results of the work are summarized as follows: (i) we verify that high-beta events are detected within well identified regions corresponding mainly to the vicinity of shock surfaces and magnetic structures, and associated with energetic particle intensity enhancements due to (a) reacceleration at shock-fronts and (b) unusually large magnetic field depressions. (ii) We define three considerable features for the high-beta events, concentrated on the next points: (a) there is an appreciable solar-activity influence on the high-beta events, during the maximum and middle solar-cycle phase, (b) the annual peak magnitude and the number of occurrences of high events are well correlated with the sunspot number, (c) the high-beta suprathermal plasma events present a spatial distribution in heliographic latitudes (HL) up to ∼±80°, and a specific important concentration on the low (−25° ? HL < −6°, 6° < HL ? 25°) and median (−45° ? HL < −25°, 25° < HL ? 45°) latitudes. We also reconfirm by a statistical analysis the results of Marhavilas and Sarris (2011), that the high-beta suprathermal plasma (β_ep > 1) events are characterized by a very large parameter β_ep (up to 1732.5), a great total duration (406 days) and a large percentage of the Ulysses-mission lifetime (which is equal to 6.34% of the total duration with usable measurements, and 11.3% of the duration in presence of suprathermal particles events).     

Solar activity dependence of total electron content derived from GPS observations over Mbarara

Vertical total electron content (VTEC) observed at Mbarara (geographic co-ordinates: 0.60°S, 30.74°E; geomagnetic coordinates: 10.22°S, 102.36°E), Uganda, for the period 2001–2009 have been used to study the diurnal, seasonal and solar activity variations. The daily values of the 10.7 cm radio flux (F_10.7) and sunspot number (R) were used to represent Solar Extreme Ultraviolet Variability (EUV). VTEC is generally higher during high solar activity period for all the seasons and increases from 0600 h LT and reaches its maximum value within 1400 h–1500 h LT. All analysed linear and quadratic fits demonstrate positive VTEC-F_10.7 and positive VTEC-R correlation, with all fits at 0000 h and 1400 h LT being significant with a confidence level of 95% when both linear and quadratic models are used. All the fits at 0600 h LT are insignificant with a confidence level of 95%. Generally, over Mbarara, quadratic fit shows that VTEC saturates during all seasons for F_10.7 more than 200 units and R more than 150 units. The result of this study can be used to improve the International Reference Ionosphere (IRI) prediction of TEC around the equatorial region of the African sector.     

Polytropic star structure analysis under Bonnor–Ebert gas sphere astrophysical configuration thorough investigating analytical solutions to the related Lane–Emden equation

In this paper, Bonnor–Ebert gas sphere model of polytropic stars has been investigated through an analytical approach. Two confirmed and well-established methods have been used: the Enhanced Lagrangian Formulation Method ELFM and the Boubaker Polynomials Expansion Scheme BPES. Solutions to the related generalized Lane–Emden equation of the second kind have been expressed and plotted. Results have given evidence to the relevance of the dimensionless Bonnor–Ebert radius, in good agreement with some recently proposed profiles.     

Definition of Wingtip Devices Shape and Dimensions for a Subsonic Airliner

The results of flow field numerical simulation on the typical wing-body prototype of the modern DLR-F4 airliner under sub- and transonic compressible air flow are presented. Using the DLR-F4 CAD model, the effect of the wingtip end plate area and of the cant angle of a typical Whitcomb winglet is studied. The dependencies of the model lift-to-drag ratio increment on the flat wingtip end plate relative area and on the cant angle of an airfoil Whitcomb winglet are obtained. The concept of an elliptic winglet with a variable cant angle that similar to the winglet used on Airbus A350 is studied. A technique is developed for solving the multi-parameter design optimization task for the Whitcomb winglet, taking the maximum lift-to-drag ratio of the wing as a criterion for optimization.     

Relaxation of electron and proton radiation belts of the earth after strong magnetic storms

During strong magnetic storms in July and November of 2004 the fluxes of trapped particles (protons and electrons of MeV energies) in the Earth’s radiation belts have increased by orders of magnitude and then decreased remaining on an enhanced level for several months. These enhancements allowed us to study the processes of relaxation of the radiation belts. Measurements of energetic particles by low-altitude satellites Coronas-F and Servis-1 have shown that predictions of the theory about the rate of pitch-angle diffusion are not always correct, giving both overestimated and underestimated values for the lifetime of energetic particles.     

Electrodynamic stabilization of earth-orbiting satellites in equatorial orbits

A satellite with electrodynamic stabilization system is considered. Based on the method of Lyapunov functions, sufficient conditions of the asymptotic stability of direct equilibrium position of this satellite in the orbital coordinate system under perturbing action of a gravitational moment are obtained. These conditions allow one to ensure a rational choice of parametric control coefficients depending on parameters of the satellite and its orbit.     

Empirical modeling of the total electron content in the ionosphere

A method of modeling the total electron content (TEC) based on the semi-empirical ionospheric model developed in Irkutsk State University is suggested. Comparison with the Klobuchar model has shown that the proposed method provides a more accurate presentation of TEC. A conclusion is drawn that the use of this method for compensation of the ionospheric error in single-frequency navigation receivers would lead to a substantial increase in the accuracy of their positioning.     

Consequences of collisions of natural cosmic bodies with the Earth’s atmosphere and surface

Possible consequences of collisions of natural cosmic bodies with the Earth’s atmosphere and surface are described. The methodological basis of classification of consequences is the solution of meteor physics equations characterizing the trajectory of a body in the atmosphere, namely, the dependence of the body’s velocity and mass on the flight altitude. The solution depends on two dimensionless parameters characterizing the drag altitude and the role of mass loss by a meteoroid during its motion in the atmosphere. Depending on values of these parameters, the degree of effect on the planetary surface considerably changes. In particular, the conditions of cratering and meteorite fall on the planetary surface are obtained. The results are presented in a simple analytical form. They quite match to the real events considered in the paper. Recommendations are given on further investigations into the important problem of interaction of cosmic bodies with planetary atmospheres.