A technique of analyzing critical forces and moments for isotropic rods of arbitrary cross-section in the general case of their complex resistance

The derivation of parametric equations for a limiting surface in the space of internal forces and moments that act in the rod cross-sections, using the basic concepts of plasticity theory and conventional hypotheses of the rod theory, is presented. The plastic properties of rod material are described by the Mises criterion. A case of small displacements and strains under static simple loading is considered. The results of solving a number of problems of constructing limiting curves in the planes of internal forces and moments are given.     

The APT on the Polar Orbiting Weather Satellites

The receipt of the Pioneer Award has given me a chance to look back over my professional life and the opportunity to take stock of how I helped shape a small part of the world. While I hope this process entertains my contemporaries, more importantly, I hope it stimulates those that are engaged in actively shaping the present. To describe the need for automatic picture transmission (APT), I must retrace the historical development of meteorological satellites. The idea for weather observations from a satellite originated with a small group of meteorologists at the U.S. Army Signal Corps Research and Development Lab. at Ft. Monmouth, N.J., and resulted in the design of Vanguard II. The Tiros and TOS series of satellites, and the design of Nimbus, followed soon thereafter. However, a faster picture dissemination than was available at that time was needed, and it was this necessity that sparked the development of APT. Nimbus was originally intended to be an operational system, but the advent of simpler, less costly stabilization systems made the Tiros evolution the clear winner. The geosynchronous weather satellites started nearly a decade later and evolved from the NASA Application Technology Satellite (ATS) series. All three systems, existing polar orbiting weather satellites, APT, and geosynchronous weather satellites, have changed meteorology and the reliability of weather forecasting profoundly.     

Simultaneous measurement of multiple radiation-induced protein expression profiles using the Luminex(TM) system.

Space flight results in the exposure of astronauts to a mixed field of radiation composed of energetic particles of varying energies, and biological indicators of space radiation exposure provides a better understanding of the associated long-term health risks. Current methods of biodosimetry have employed the use of cytogenetic analysis for biodosimetry, and more recently the advent of technological progression has led to advanced research in the use of genomic and proteomic expression profiling to simultaneously assess biomarkers of radiation exposure. We describe here the technical advantages of the Luminex(TM) 100 system relative to traditional methods and its potential as a tool to simultaneously profile multiple proteins induced by ionizing radiation. The development of such a bioassay would provide more relevant post-translational dynamics of stress response and will impart important implications in the advancement of space and other radiation contact monitoring.     

Forecasting the future in space: Highlights from the TechCast Project

Space technology and activities have changed markedly from the early days of the space era and are continuing to develop rapidly. The TechCast Project—set up to pool the knowledge of experts in the scientific fields—includes space in its predictions. Here its president reports on its space forecasts for the 21st century. The importance of the shift towards the privatization of space is noted and the near-to-medium-term impossibility of interstellar travel conceded. Contact with ETI is deemed much more likely, however.     

Genomic instability and tumorigenic induction in immortalized human bronchial epithelial cells by heavy ions

Carcinogenesis is postulated to be a progressive multistage process characterized by an increase in genomic instability and clonal selection with each mutational event endowing a selective growth advantage. Genomic instability as manifested by the amplification of specific gene fragments is common among tumor and transformed cells. In the present study, immortalized human bronchial (BEP2D) cells were irradiated with graded doses of either 1GeV/nucleon ⁵⁶Fe ions or 150 keV/μm alpha particles. Transformed cells developed through a series of successive steps before becoming tumorigenic in nude mice. Tumorigenic cells showed neither ras mutations nor deletion in the p16 tumor suppressor gene. In contrast, they harbored mutations in the p53 gene and over-expressed cyclin D1. Genomic instability among transformed cells at various stage of the carcinogenic process was examined based on frequencies of PALA resistance. Incidence of genomic instability was highest among established tumor cell lines relative to transformed, non-tumorigenic and control cell lines. Treatment of BEP2D cells with a 4 mM dose of the aminothiol WR-1065 significantly reduced their neoplastic transforming response to ⁵⁶Fe particles. This model provides an opportunity to study the cellular and molecular mechanisms involved in malignant transformation of human epithelial cells by heavy ions.     

The radiation continuum model of light and the Galilean invarianceof Maxwell's equations

The original basis for the Lorentz transformations, and thus special relativity, was the assumption that the observed velocity of interaction of light with matter represents a unique velocity of the electromagnetic wave. This arbitrary decision is not borne out by Maxwell's theories or by any test that might prove that EM energy actually travels in a continuum of velocities. The second postulate as stated by Einstein does not deserve the status of a postulate, as it is at once overly restrictive and ultimately phenomenological-the nature of c is based on experimental measurement rather than on analysis of first principles. The radiation continuum model's (RCM) modified second postulate, however, says nothing about the actual propagation of EM energy, but only of the relative speed with which it must interact with matter to be detected. Utilizing this modified light principle we obtain an intuitive Galilean form invariance for Maxwell's equations. RCM places no upper limit on attainable velocities, and allows for the possibility of communications between humans or particles at speeds far in excess of c. This precludes many of the compatibility problems between the highly successful quantum mechanics and relativity theory     

Force on a coil moving above a grid structure

The force on a coil moving with a high-speed parallel to a conducting grid consisting of parallel tubes is investigated. The coil performs a rebound motion or an oscillatory heave motion when pressed toward the grid by reactive on-board engines. The coil is approximated by two parallel wires moving parallel to the grid tubes. The corresponding electrodynamic problem is two dimensional and is solved by expansions in terms of Bessel functions. Expressions are derived for the lift and drag force as well as the heat generated in the tubes in the limit of strong skin effect. The dependence on the grid spacing is analysed in the approximation of no mutual inductance between the tubes. Two specific applications are a shunt deflecting the coil, and a funnel leading to multiple reflection. Finally, the varying magnetic flux threading the coil is considered and the thermal load of the coil is estimated.     

On the structure and dynamics of the thermosphere

Thermospheric temperature, composition and wind measurements from the Dynamics Explorer satellite (DE-2) are interpreted using a three dimensional, multiconstituent spectral model. The analysis accounts for tides driven by the absorbed solar radiation as well as energy and momentum coupling involving the magnetosphere and lower atmosphere. We discuss phenomena associated with the annual tide, polar circulation, magnetic storms and substorms.     

The biological clock of Neurospora in a microgravity environment.

The circadian rhythm of conidiation in Neurospora crassa is thought to be an endogenously derived circadian oscillation; however, several investigators have suggested that circadian rhythms may, instead, be driven by some geophysical time cue(s). An experiment was conducted on space shuttle flight STS-9 in order to test this hypothesis; during the first 7-8 cycles in space, there were several minor alterations observed in the conidiation rhythm, including an increase in the period of the oscillation, an increase in the variability of the growth rate and a diminished rhythm amplitude, which eventually damped out in 25% of the flight tubes. On day seven of flight, the tubes were exposed to light while their growth fronts were marked. Some aspect of the marking process reinstated a robust rhythm in all the tubes which continued throughout the remainder of the flight. These results from the last 86 hours of flight demonstrated that the rhythm can persist in space. Since the aberrant rhythmicity occurred prior to the marking procedure, but not after, it was hypothesized that the damping on STS-9 may have resulted from the hypergravity pulse of launch. To test this hypothesis, we conducted investigations into the effects of altered gravitational forces on conidiation. Exposure to hypergravity (via centrifugation), simulated microgravity (via the use of a clinostat) and altered orientations (via alterations in the vector of a 1 g force) were used to examine the effects of gravity upon the circadian rhythm of conidiation.     

History of monopulse radar in the USSR

Monopulse radars have played an important role in air and missile defense systems since the development of the monopulse technique in the late 1940s. This paper outlines the application of monopulse radars in Russian defense systems, starting with the Moscow ABM system and continuing in instrumentation and air defense radars now widely deployed in Russia and elsewhere