Topological biosignatures: large-scale structure of chemical networks from biology and astrochemistry

The chemical basis of life involves more than simply the presence of biological molecules; biochemical systems embody a complex network of reactions with characteristic topological features. At the same time, chemical complexity is also present in nonbiological contexts, inviting us to clarify the relationship between chemistry and life through comparative studies. This study examines chemical networks from biology (the metabolism of E. coli) and astronomy (gas-phase reactions in dark molecular clouds) to establish common topological features that may be generic for any complex chemical system, as well as clear differences that may be topological signatures of life. The biological and astrochemical networks exhibit different scaling behaviors, and the network motifs found in the two systems show similarities as well as significant differences. The PageRank algorithm was used to quantify the degree to which individual species act primarily as products or reactants; in the metabolic network, these two roles are nearly identical for most species, whereas the astrochemical network shows a clearer partitioning into reactants and products.     

Doppler Compensation & Single Pulse Imaging using Adaptive Pulse Compression

The effects of target Doppler are addressed in relation to adaptive receive processing for radar pulse compression. To correct for Doppler-induced filter mismatch over a single pulse, the Doppler-compensated adaptive pulse compression (DC-APC) algorithm is presented whereby the respective Doppler shifts for large target returns are jointly estimated with the illuminated range profile and subsequently incorporated into the original APC adaptive receive filter formulation. As a result, the Doppler-mismatch-induced range sidelobes can be suppressed thereby regaining a significant portion of the sensitivity improvement that is possible when applying adaptive pulse compression (APC) without the existence of significant Doppler mismatch. In contrast, instead of compensating for Doppler mismatch, the single pulse imaging (SPI) algorithm generalizes the APC formulation for a bank of Doppler-shifted matched filters thereby producing a sidelobe-suppressed range-Doppler image from the return signal of a single radar pulse which is applicable for targets with substantial variation in Doppler. Both techniques are based on the recently proposed APC algorithm and its generalization, the multistatic adaptive pulse compression (MAPC) algorithm, which have been shown to be effective for the suppression of pulse compression range sidelobes thus dramatically increasing the sensitivity of pulse compression radar.     

Ares I–X Flight Test Vehicle similitude to the Ares I Crew Launch Vehicle

The Ares I–X Flight Test Vehicle is the first in a series of flight test vehicles that will take the Ares I Crew Launch Vehicle design from development to operational capability. Ares I–X is scheduled for a 2009 flight date, early enough in the Ares I design and development process so that data obtained from the flight can impact the design of Ares I before its Critical Design Review. Decisions on Ares I–X scope, flight test objectives, and FTV fidelity were made prior to the Ares I systems requirements being baselined. This was necessary in order to achieve a development flight test to impact the Ares I design. Differences between the Ares I–X and the Ares I configurations are artifacts of formulating this experimental project at an early stage and the natural maturation of the Ares I design process. This paper describes the similarities and differences between the Ares I–X Flight Test Vehicle and the Ares I Crew Launch Vehicle. Areas of comparison include the outer mold line geometry, aerosciences, trajectory, structural modes, flight control architecture, separation sequence, and relevant element differences. Most of the outer mold line differences present between Ares I and Ares I–X are minor and will not have a significant effect on overall vehicle performance. The most significant impacts are related to the geometric differences in Orion Crew Exploration Vehicle at the forward end of the stack. These physical differences will cause differences in the flow physics in these areas. Even with these differences, the Ares I–X flight test is poised to meet all five primary objectives and six secondary objectives. Knowledge of what the Ares I–X flight test will provide in similitude to Ares I—as well as what the test will not provide—is important in the continued execution of the Ares I–X mission leading to its flight and the continued design and development of Ares I.     

Bacterial community in ancient Siberian permafrost as characterized by culture and culture-independent methods

The microbial composition of ancient permafrost sediments from the Kolyma lowland of Northeast Eurasia was examined through culture and culture-independent approaches. These sediments have been continuously frozen for 5,000 to 2-3 million years. A total of 265 Bacteria 16S rRNA gene sequences were amplified from the permafrost total-community genomic DNA and screened by amplified ribosomal 16S rRNA restriction analysis. Members of three major lineages were found: gamma-Proteobacteria (mostly Xanthomonadaceae), Actinobacteria, and Firmicutes. We also determined partial 16S rRNA gene sequences of 49 isolates from a collection of 462 aerobes isolated from these sediments. The bacteria included Actinomycetales (Arthrobacter and Microbacteriaceae); followed by the Firmicutes (Exiguobacterium and Planomicrobium); the Bacteroidetes (Flavobacterium); the gamma-Proteobacteria (Psychrobacter); and the alpha-Proteobacteria (Sphingomonas). Both culture and culture-independent approaches showed the presence of high and low G+C Gram-positive bacteria and gamma-Proteobacteria. Some of the 16S rRNA gene sequences of environmental clones matched those of Arthrobacter isolates. Two-thirds of the isolates grew at -2.5 degrees C, indicating that they are psychroactive, and all are closely related to phylogenetic groups with strains from other cold environments, mostly commonly from Antarctica. The culturable and non-culturable microorganisms found in the terrestrial permafrost provide a prototype for possible life on the cryogenic planets of the Solar System.     

Progress in the study of homologous flares on the sun — Part II

Studies of groups of homologous flares in active regions in 1980 have been made using a variety of space and ground based instruments. Detailed properties of three of these groups have been studied, and are combined to form a possible sequence of events.     

Comet Halley: Nucleus and jets (results of the VEGA mission)

The VEGA-1 and VEGA-2 spacecraft made their closest approach to Comet Halley on 6 and 9 March, respectively. In this paper those results of the onboard imaging experiment which were obtained around closest approach are discussed. The nucleus of the comet was clearly identifiable as an irregularly shaped object, with overall dimensions of (16±1)×(8±1)×(8±1) km. The nucleus rotates in the prograde sense about an axis nearly perpendicular to the orbital plane with a period of 53±2 hours. Its albedo is only $\text{0.04±}\text{0.02}\text{0.01}$ Many of the jet features observed during the second fly-by have been spatially reconstructed. Their sources form a quasi-linear structure on the surface. The dust above the surface is shown to be generally optically thin with the exception of certain specific dust jets. Brightness features on the surface are clearly seen. Correlating our data with other measurements, we conclude that the dirty snow-ball model will probably need to be revised.     

Protein crystal growth aboard the U.S. space shuttle flights STS-31 and STS-32.

The first microgravity protein crystal growth experiments were performed on Spacelab I by Littke and John. These experiments indicated that the space grown crystals, which were obtained using a liquid-liquid diffusion system, were larger than crystals obtained by the same experimental system on earth. Subsequent experiments were performed by other investigators on a series of space shuttle missions from 1985 through 1990. The results from two of these shuttle flights (STS-26 and STS-29) have been described previously. The results from these missions indicated that the microgravity grown crystals for a number of different proteins were larger, displayed more uniform morphologies, and yielded diffraction data to significantly higher resolutions than the best crystals of these proteins grown on earth. This paper presents the results obtained from shuttle flight STS-32 (flown in January, 1990) and preliminary results from the most recent shuttle flight, STS-31 (flown in April, 1990).     

X-ray observations of Vela-X

Exosat ME observations of the Vela-X region are presented. It is found that the 2–10 keV emission is divided into two components. One is associated with the rulsar but is probably extended by 10–20 arc minutes, the other is associated with the Vela-X radio nebula and is probably more extended ($\text{? 1}\text{degree}$). The Vela-X component is softer than the pulsar component. No pulsed emission is observed.     

Sputnik fever — again?

The author offers some comments on the drawbacks of another US-Soviet space race. She compares the relative positions of the USA and the USSR in various areas of space science and technology, and concludes that the USSR does not lead in all areas. More importantly, she argues that it is distressing still to be portraying the superpowers as in a race in space. ‘Sputnik fever’ the first time round showed that a space race does not lead to a strong, long-term US space programme. She argues that cooperation in some areas — perhaps a trip to Mars — could b an alternative.