Choroidal responses in microgravity. (SLS-1, SLS-2 and hindlimb-suspension experiments)

Fluid and electrolyte shifts occuring during human spaceflight have been reported and investigated at the level of blood, cardio-vascular and renal responses. Very few data were available concerning the cerebral fluid and electrolyte adaptation to microgravity, even in animal models. It is the reason why we developed several studies focused on the effects of spaceflight (SLS-1 and SLS-2 programs, carried on NASA STS 40 and 56 missions, which were 9- and 14-day flights, respectively), on structural and functional features of choroid plexuses, organs which secrete 70–90 % of cerebrospinal fluid (CSF) and which are involved in brain homeostasis. Rats flown aboard space shuttles were sacrificed either in space (SLS-2 experiment, on flight day 13) or 4–8 hours after landing (SLS-1 and SLS-2 experiments). Quantitative autoradiography performed by microdensitometry and image analysis, showed that lateral and third ventricle choroid plexuses from rats flown for SLS-1 experiment demonstrated an increased number (about x 2) of binding sites to natriuretic peptides (which are known to be involved in mechanisms regulating CSF production). Using electron microscopy and immunocytochemistry, we studied the cellular response of choroid plexuses, which produce cerebrospinal fluid (CSF) in brain lateral, third and fourth ventricles. We demonstrated that spaceflight (SLS-2 experiment, inflight samples) induces changes in the choroidal cell structure (apical microvilli, kinocilia organization, vesicle accumulation) and protein distribution or expression (carbonic anhydrase II, water channels,…). These observations suggested a loss of choroidal cell polarity and a decrease in CSF secretion. Hindlimb-suspended rats displayed similar choroidal changes. All together, these results support the hypothesis of a modified CSF production in rats during long-term (9, 13 or 14 days) adaptations to microgravity.     

改善推进剂老化和低温物理性质的键合剂系统

新的混合键合剂系统用于端羟基聚丁二烯推进剂配方时,推进剂的高温老化特性和低温物理性质都有很大改善。混合键合剂系统由 MT_4[2.0克分子三-1-(2-甲基氮丙啶)膦化氧、0.7克分子已二酸和0.3克分子酒石酸的反应产物]、HX752[双-间苯二酰-1-(2-甲基)氨丙啶]和 BIDE(丁基亚胺二乙醇)组成,其重量百分含量分别占推进剂组成的0.10～0.20%、0.10～0.20%和0.02～0.05%。     

螺栓挤压推力终止系统验证试验

本文总结了螺栓挤压推力终止系统(BETTS)的设计、研制和验证试验。该系统在阿诺德工程研制中心(AEDC)进行了多次冷试,一次海平面热试和两次高空点火推力终止试验,试验所用的发动机是政府向化学系统分公司提供的“民兵”发动机空壳体装药后制成的。通过大发动机热试,证明本计划所验证的这种BETTS可以消除前部碎片,大大地简化药柱和发动机壳体的设计,提高末级性能。另外,这种方法设计简单,从而可以降低推进系统的成本。BETTS用爆炸螺栓和挤压螺栓的组合代替连接喷管法兰和发动机壳体法兰的普通螺栓。接到指令后,爆炸螺栓立即打开,喷管循着挤压螺栓向后平移,发动机气体迅速排出,从而使推进剂熄火。挤压螺栓控制着喷管的移动速度和最大运动行程。以前根据NO.F04611—75—C—0044合同(CSD计划2549)曾成功地在缩比发动机上进行了BETTS热试和在飞行重量的“民兵”Ⅲ第三级发动机上进行了冷试。     

On the correlation between individual biochemical parameters of human blood serum following space flight and their basal values

The article presents data concerning the osmolality and concentration of electrolytes and hormones regulating their balance for blood serum of 223 cosmonauts and astronauts. The obtained results allow us to judge the constancy of physicochemical parameters for the blood serum of healthy individuals and how they react to extreme conditions of space flight. The parameters used for evaluation included not just absolute values for the examined indices, but also how they responded to space flight, the dependence on baseline values and the interrelationship between ions. These data are important to predict the effect of exposure to extreme conditions and point to what extent the effect depends on the characteristics of the individual.     

聚合物基复合材料自修复体系的构成与修复机制分析

介绍了聚合物基自修复复合材料的分类、构成及自修复机制,以被动模式的埋植式修复体系为重点进行了详细的分析.在此基础上,提出了一种新的被动模式自修复体系设计.     

一种整体式天然气压缩机气阀故障诊断技术研究CSCD

整体式天然气压缩机在石油化工领域广泛应用,压缩机的正常工作对安全生产具有重要意义。为了有效诊断整体式压缩机气阀部件的故障,采用了Daubechies小波基函数对ZTY470型整体式天然气压缩机气阀振动信号的分解重构原理,详细介绍了以振动信号的能量为故障特征的故障诊断过程。对气阀阀片断裂和弹簧断裂的故障振动信号进行了小波包分析,并与正常工作时的信号进行了对比。实验表明该方法能准确的进行故障诊断和故障定位,证明了对整体式天然气压缩机气阀故障诊断的有效性。     

前向数据接入方式对导航星座网络通信性能的影响分析

对采用时分多址轮询建链体制的导航星座星间链路网络,为了指导星间链路网络地面前向数据接入的应用,分析了不同地面前向数据接入方式的星-星-地联合数据交互机制及其对网络通信性能的影响,并结合应用代价给出了综合评价和使用建议.以前向数据最快路径接入方式和固定节点接入方式为代表,分析了星间链路网络与地面间星-星-地联合数据交互机...     

金融危机影响滞后采取措施应对寒冬——金融危机下的商用飞机制造业

在金融危机向实体经济蔓延的情况下,人们普遍关心,航空制造业将发生怎样的变化？飞机市场是否将再次面临新飞机订单下降,原有储备订单被取消或推迟交付的情况？     

NASCOM网络管理结构的重建

Nascom地面通信系统的研制始于1958年的先驱计划。低速率系统(速率低于9.6kbps)的开发遵循现有标准。但高速系统没有可比较的标准,因此使用专用协议和定制硬件开发。 自地面保障系统建成后,技术又取得了巨大的进步。有了计算机硬件、软件和高速通信标准,而且现有工作站的性能超出了地面系统研制中使用的主机性能。 Nascom正处于改进其保障系统以及提供更多服务的过程中。信息交换系统(MSS),通信地址处理器(CAP)以及多路复用/分路器(MDM)自动控制系统(MACS)是几例使用X—windows,Motifus及简易网络管理协议(SNMP)等标准开发出的Nascom系统。而且,地球观测系统(EOS)通信(ECOM)计划把标准作为整个网络的组成部分来强调。向标准发展在改进操作质量的同时缩减了研制、维护和互操作费用。 已经制定了将Nascom网络和系统综合到公共网络管理结构中的设施和资源管理器(FARM)计划。结构中最大限度地采用标准和实现计算机自动化将带来成本不断下降,操作效率不断提高。第一步总是得出Nascom总的需求,并确定全部现有管理系统共有的功能。确定这些公共功能可在管理结构中实现过程的再利用并促进整个Nascom网络更多地采用自动化。 MSS、CAP、MACS和Ecom计划通过降低成本和提高质量。表明了商业成品(COTS)和标准的潜在价