ATM performance measurement in Europe,the US and China

Air traffic management (ATM) performance and the metrics used in its assessment are investigated for the first time across the three largest ATM world regions: Europe, the US and China. The market structure and flow management practices of each region are presented. A wide range of performance data across these three regions is synthesised. For topological and performance assessment, the notion of a 'sufficient' sample is often non-intuitive: many metrics may behave non-monotonically as a function of sampling fraction. Missing and under-developed metrics are identified, and the need for a balance between standardisation and flexibility is proposed. Longitudinal and cross-sectional metric trade-offs are identified.     

Theories and Observations of Ion Energization and Outflow in the High Latitude Magnetosphere

A review is given of several mechanisms causing outflow at high latitudes of ionospheric ions to the terrestrial magnetosphere. The upward ion motion along the geomaagnetic field can be divided into several categories, including polar wind, bulk ion outflow in the auroral region, upwelling ions and ion conics and beams. More than one ion energization mechanism can be operating within each category, and a combination of categories is important for the total ion outflow.     

Theoretical Aspects of Dark Matter Detection

Direct and indirect dark matter detection relies on the scattering of the dark matter candidate on nucleons or nuclei. Here, attention is focused on dark matter candidates (neutralinos) predicted in the minimal supersymmetric standard model and its constrained version with universal input soft supersymmetry-breaking masses. Current expectations for elastic scattering cross sections for neutralinos on protons are discussed with particular attention to satisfying all current accelerator constraints as well as insuring a sufficient cosmological relic density to account for the dark matter in the universe.     

The origin and early evolution of membrane channels

The origin and early evolution of ion channels are considered from the point of view that the transmembrane segments of membrane proteins are structurally quite simple and do not require specific sequences to fold. We argue that the transport of solute species, especially ions, required an early evolution of efficient transport mechanisms, and that the emergence of simple ion channels was protobiologically plausible. We also argue that, despite their simple structure, such channels could possess properties that, at the first sight, appear to require markedly greater complexity. These properties can be subtly modulated by local modifications to the sequence rather than global changes in molecular architecture. In order to address the evolution and development of ion channels, we focus on identifying those protein domains that are commonly associated with ion channel proteins and are conserved throughout the three main domains of life (Eukarya, Bacteria, and Archaea). We discuss the potassium-sodium-calcium superfamily of voltage-gated ion channels, mechanosensitive channels, porins, and ABC-transporters and argue that these families of membrane channels have sufficiently universal architectures that they can readily adapt to the diverse functional demands arising during evolution.     

Contents of Volume 2

Volume Contents

Contents of Volume 2     

Observations from a 4-year contamination study of a sample depth profile through Martian meteorite Nakhla

Morphological, compositional, and biological evidence indicates the presence of numerous well-developed microbial hyphae structures distributed within four different sample splits of the Nakhla meteorite obtained from the British Museum (allocation BM1913,25). By examining depth profiles of the sample splits over time, morphological changes displayed by the structures were documented, as well as changes in their distribution on the samples, observations that indicate growth, decay, and reproduction of individual microorganisms. Biological staining with DNA-specific molecular dyes followed by epifluorescence microscopy showed that the hyphae structures contain DNA. Our observations demonstrate the potential of microbial interaction with extraterrestrial materials, emphasize the need for rapid investigation of Mars return samples as well as any other returned or impactor-delivered extraterrestrial materials, and suggest the identification of appropriate storage conditions that should be followed immediately after samples retrieved from the field are received by a handling/curation facility. The observations are further relevant in planetary protection considerations as they demonstrate that microorganisms may endure and reproduce in extraterrestrial materials over long (at least 4 years) time spans. The combination of microscopy images coupled with compositional and molecular staining techniques is proposed as a valid method for detection of life forms in martian materials as a first-order assessment. Time-resolved in situ observations further allow observation of possible (bio)dynamics within the system.     

Survival and germinability of Bacillus subtilis spores exposed to simulated Mars solar radiation: implications for life detection and planetary protection

Bacterial spores have been considered as microbial life that could survive interplanetary transport by natural impact processes or human spaceflight activity. Deposition of terrestrial microbes or their biosignature molecules onto the surface of Mars could negatively impact life detection experiments and planetary protection measures. Simulated Mars solar radiation, particularly the ultraviolet component, has been shown to reduce spore viability, but its effect on spore germination and resulting production of biosignature molecules has not been explored. We examined the survival and germinability of Bacillus subtilis spores exposed to simulated martian conditions that include solar radiation. Spores of B. subtilis that contain luciferase resulting from expression of an sspB-luxAB gene fusion were deposited on aluminum coupons to simulate deposition on spacecraft surfaces and exposed to simulated Mars atmosphere and solar radiation. The equivalent of 42 min of simulated Mars solar radiation exposure reduced spore viability by nearly 3 logs, while germination-induced bioluminescence, a measure of germination metabolism, was reduced by less than 1 log. The data indicate that spores can retain the potential to initiate germination-associated metabolic processes and produce biological signature molecules after being rendered nonviable by exposure to Mars solar radiation.     

Cometary Dust

This review presents our understanding of cometary dust at the end of 2017. For decades, insight about the dust ejected by nuclei of comets had stemmed from remote observations from Earth or Earth’s orbit, and from flybys, including the samples of dust returned to Earth for laboratory studies by the Stardust return capsule. The long-duration Rosetta mission has recently provided a huge and unique amount of data, obtained using numerous instruments, including innovative dust instruments, over a wide range of distances from the Sun and from the nucleus. The diverse approaches available to study dust in comets, together with the related theoretical and experimental studies, provide evidence of the composition and physical properties of dust particles, e.g., the presence of a large fraction of carbon in macromolecules, and of aggregates on a wide range of scales. The results have opened vivid discussions on the variety of dust-release processes and on the diversity of dust properties in comets, as well as on the formation of cometary dust, and on its presence in the near-Earth interplanetary medium. These discussions stress the significance of future explorations as a way to decipher the formation and evolution of our Solar System.     

The Supermassive Black Hole—Galaxy Connection

The observed scaling relations imply that supermassive black holes (SMBH) and their host galaxies evolve together. Near-Eddington winds from the SMBH accretion discs explain many aspects of this connection. The wind Eddington factor \(\dot{m}\) should be in the range ～1–30. A factor \(\dot{m}\sim 1\) give black hole winds with velocities v～0.1c, observable in X-rays, just as seen in the most extreme ultrafast outflows (UFOs). Higher Eddington factors predict slower and less ionized winds, observable in the UV, as in BAL QSOs. In all cases the wind must shock against the host interstellar gas and it is plausible that these shocks should cool efficiently. There is detailed observational evidence for this in some UFOs. The wind sweeps up the interstellar gas into a thin shell and propels it outwards. For SMBH masses below a certain critical (M–σ) value, all these outflows eventually stall and fall back, as the Eddington thrust of the wind is too weak to drive the gas to large radii. But once the SMBH mass reaches the critical M–σ value the global character of the outflow changes completely. The wind shock is no longer efficiently cooled, and the resulting thermal expansion drives the interstellar gas far from the black hole, which is unlikely to grow significantly further. Simple estimates of the maximum stellar bulge mass M _b allowed by self-limited star formation show that the SMBH mass is typically about 10^?3 M _b at this point, in line with observation. The expansion-driven outflow reaches speeds v _out?1200 km?s^?1 and drives rates \(\dot{M}_{\mathrm{out}}\sim 4000~\mathrm {M}_{\odot }\,\mathrm{yr}^{-1}\) in cool (molecular) gas, giving a typical outflow mechanical energy L _mech?0.05L _Edd, where L _Edd is the Eddington luminosity of the central SMBH. This is again in line with observation. These massive outflows may be what makes galaxies become red and dead, and can have several other potentially observable effects. In particular they have the right properties to enrich the intergalactic gas with metals. Our current picture of SMBH-galaxy coevolution is still incomplete, as there is no predictive theory of how the hole accretes gas from its surroundings. Recent progress in understanding how large-scale discs of gas can partially cancel angular momentum and promote dynamical infall offers a possible way forward.