Impact of rain on wave retrieval from Sentinel-1 synthetic aperture radar images in tropical cyclones

The main objective of our work was to investigate the impact of rain on wave observations from C-band (~5.3 GHz) synthetic aperture radar (SAR) in tropical cyclones. In this study, 10 Sentinel-1 SAR images were available from the Satellite Hurricane Observation Campaign, which were taken under cyclonic conditions during the 2016 hurricane season. The third-generation wave model, known as Simulating WAves Nearshore (SWAN) (version 41.31), was used to simulate the wave fields corresponding to these Sentinel-1 SAR images. In addition, rainfall data from the Tropical Rainfall Measuring Mission satellite passing over the spatial coverage of the Sentinel-1 SAR images were collected. The simulated results were validated against significant wave heights (SWHs) from the Jason-2 altimeter and European Centre for Medium-Range Weather Forecasts data, revealing a root mean square error (RMSE) of ~0.5 m with a 0.25 scatter index. Winds retrieved from the VH-polarized Sentinel-1 SAR images using the Sentinel-1 Extra Wide-swath Mode Wind Speed Retrieval Model after Noise Removal were taken as prior information for wave retrieval. It was discovered that rain did indeed affect the SAR wave retrieval, as evidenced by the 3.21-m RMSE of SWHs between the SAR images and the SWAN model, which was obtained for the ~1000 match-ups with raindrops. The raindrops dampened the wave retrieval when the rain rate was < ~5 mm/hr; however, they enhanced wave retrieval for higher rain rates. It was also found that the portion of the rain-induced ring wave with a wave number > 0.05 rad/m (~125 m wavelength) was clearly observed in the SAR-derived wave spectra.     

The role of DNA repair on cell killing by charged particles.

It can be noted that it is not simple double strand breaks (dsb) but the non-reparable breaks that are associated with high biological effectiveness in the cell killing effect for high LET radiation. Here, we have examined the effectiveness of fast neutrons and low (initial energy = 12 MeV/u) or high (135 MeV/u) energy charged particles on cell death in 19 mammalian cell lines including radiosensitive mutants. Some of the radiosensitive lines were deficient in DNA dsb repair such as LX830, M10, V3, and L5178Y-S cells and showed lower values of relative biological effectiveness (RBE) for fast neutrons if compared with their parent cell lines. The other lines of human ataxia-telangiectasia fibroblasts, irs 1, irs 2, irs 3 and irs1SF cells, which were also radiosensitive but known as proficient in dsb repair, showed moderated RBEs. Dsb repair deficient mutants showed low RBE values for heavy ions. These experimental findings suggest that the DNA repair system does not play a major role against the attack of high linear energy transfer (LET) radiations. Therefore, we hypothesize that a main cause of cell death induced by high LET radiations is due to non-reparable dsb, which are produced at a higher rate compared to low LET radiations.     

Austrian dose measurements onboard space station MIR and the International Space Station--overview and comparison.

The Atominstitute of the Austrian Universities has conducted various space research missions in the last 12 years in cooperation with the Institute for Biomedical Problems in Moscow. They dealt with the exact determination of the radiation hazards for cosmonauts and the development of precise measurement devices. Special emphasis will be laid on the last experiment on space station MIR the goal of which was the determination of the depth distribution of absorbed dose and dose equivalent in a water filled Phantom. The first results from dose measurements onboard the International Space Station (ISS) will also be discussed. The spherical Phantom with a diameter of 35 cm was developed at the Institute for Biomedical Problems and had 4 channels where dosimeters can be exposed in different depths. The exposure period covered the timeframe from May 1997 to February 1999. Thermoluminescent dosimeters (TLDs) were exposed inside the Phantom, either parallel or perpendicular to the hull of the spacecraft. For the evaluation of the linear energy transfer (LET), the high temperature ratio (HTR) method was applied. Based on this method a mean quality factor and, subsequently, the dose equivalent is calculated according to the Q(LET infinity) relationship proposed in ICRP 26. An increased contribution of neutrons could be detected inside the Phantom. However the total dose equivalent did not increase over the depth of the Phantom. As the first Austrian measurements on the ISS dosimeter packages were exposed for 248 days, starting in February 2001 at six different locations onboard the ISS. The Austrian dosimeter sets for this first exposure on the ISS contained five different kinds of passive thermoluminescent dosimeters. First results showed a position dependent absorbed dose rate at the ISS.     

Simulation experiments of the effect of space environment on bacteriophage and DNA thin films.

The main goal of PUR experiment (phage and uracil response) is to examine and quantify the effect of specific space conditions on nucleic acid models. To achieve this an improved method was elaborated for the preparation of DNA and bacteriophage thin films. The homogeneity of the films was controlled by UV spectroscopy and microscopy. To provide experimental evidence for the hypothesis that interplanetary transfer of the genetic material is possible, phage T7 and isolated T7 DNA thin films have been exposed to selected space conditions: intense UVC radiation (lambda=254 nm) and high vacuum (10(-4) Pa). The effects of DNA hydration, conformation and packing on UV radiation damage were examined. Characteristic changes in the absorption spectrum, in the electrophoretic pattern of DNA and the decrease of the amount of PCR products have been detected indicating the photodamage of isolated and intraphage DNA.     

RPC-MAG The Fluxgate Magnetometer in the ROSETTA Plasma Consortium

The fluxgate magnetometer experiment onboard the ROSETTA spacecraft aims to measure the magnetic field in the interaction region of the solar wind plasma with comet 67P/Churyumov-Gerasimenko. It consists of a system of two ultra light (about 28 g each ) triaxial fluxgate magnetometer sensors, mounted on the 1.5 m long spacecraft boom. The measurement range of each sensor is ±16384 nT with quantization steps of 31 pT. The magnetometer sensors are operated with a time resolution of up to 0.05 s, corresponding to a bandwidth of 0–10 Hz. This performance of the RPC-MAG sensors allows detailed analyses of magnetic field variations in the cometary environment. RPC-MAG furthermore is designed to study possible remnant magnetic fields of the nucleus, measurements which will be done in close cooperation with the ROSETTA lander magnetometer experiment ROMAP.     

Carbon dioxide and oxygen budgets of a plant cultural system in a CELSS--a case of cultivation of lettuce and turnips.

In order to collect basic data about CO2 and O2 budgets of a plant cultural system in a CELSS, the variation of the CO2 absorption rates of lettuce and turnips were observed during the growing period, under different conditions. The O2 release rates were deduced from the CO2 absorption rates multiplied by 32/44. As a result, when the light intensity, the photoperiod and the atmospheric CO2 concentration increased, the rates also increased. The effects on the turnips were more significant than those on the lettuce. Turnips at 310 micromoles/m2/s of PPFD, 24 hours of photoperiod and 1100 ppm of CO2 concentration grew most actively in the present experimental conditions. One turnip absorbed 32.3 g CO2 and released 23.5 g O2 for 6 days between 24 days and 30 days after sowing.     

Active damping control of vibrational systems

The problem of vibration suppression in large flexible space structure (LFSS) is investigated. Based on the structure property of LFSS, an active damping strategy is proposed to effectively attenuate the critical vibrations of the structure subject to modeling uncertainty and external disturbance. Control algorithms are derived with the aim of suppressing both the vibrating magnitude and vibrating rate to an acceptable level. It is shown that the strategy exhibits robust and adaptive properties and is truly model-independent. The novelty of the proposed approach lies in the fact that it is fairly easy to set up the strategy and the overall computation involved is much less than any other strategies available to date. A two-bay truss is used to verify the validity of the proposed approach     

The influence of dose, dose-rate and particle fragmentation on cataract induction by energetic iron ions.

Because activities in space necessarily involve chronic exposure to a heterogeneous charged particle radiation field it is important to assess the influence of dose-rate and the possible modulating role of heavy particle fragmentation on biological systems. Using the well-studied cataract model, mice were exposed to plateau 600 MeV/amu 56Fe ions either as acute or fractionated exposures at total doses of 5 - 504 cGy. Additional groups of mice received 20, 360 and 504 cGy behind 50 mm of polyethylene, which simulates body shielding. The reference radiation consisted of 60Co gamma radiation. The animals were examined by slit lamp biomicroscopy over their three year life spans. In accordance with our previous observations with heavy particles, the cataractogenic potential of the 600 MeV/amu 56Fe ions was greater than for low-LET radiation and increased with decreasing dose relative to gamma-rays. Fractionation of a given dose of 56Fe ions did not reduce the cataractogenicity of the radiation compared to the acute regimen. Fragmentation of the beam in the polyethylene did not alter the cataractotoxicity of the ions, either when administered singly or in fractions.     

Molecular alterations in tumorigenic human bronchial and breast epithelial cells induced by high LET radiation.

Carcinogenesis is a multi-stage process with sequence of genetic events governing the phenotypic expression of a series of transformation steps leading to the development of metastatic cancer. In the present study, immortalized human bronchial (BEP2D) and breast (MCF-10F) cells were irradiated with graded doses of either 150 keV/micrometer alpha particles or 1 GeV/nucleon 56Fe ions. Transformed cells developed through a series of successive steps before becoming tumorigenic in nude mice. Cell fusion studies indicated that radiation-induced tumorigenic phenotype in BEP2D cells could be completely suppressed by fusion with non-tumorigenic BEP2D cells. The differential expressions of known genes between tumorigenic bronchial and breast cells induced by alpha particles and their respective control cultures were compared using cDNA expression array. Among the 11 genes identified to be differentially expressed in BEP2D cells, three (DCC, DNA-PK and p21(CIP1)) were shown to be consistently down-regulated by 2 to 4 fold in all the 5 tumor cell lines examined. In contrast, their expressions in the fusion cell lines were comparable to control BEP2D cells. Similarly, expression levels of a series of genes were found to be altered in a step-wise manner among tumorigenic MCF-10F cells. The results are highly suggestive that functional alterations of these genes may be causally related to the carcinogenic process.