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101.
Based on the first-order shear deformation theory, this paper explores the analytical methods for eigenbuckling of symmetric cross-ply rectangular composite laminates with a pair of parallel edges simply supported and the remaining two edges arbitrarily constrained. The main con-tribution of present paper lies in two aspects: one is to present a simple and effective analytical method, namely, the separation-of-variables method, which can generate the closed-form buckling solutions without any computational difficulty;the other is to incorporate the accurate computation method of exponential matrix into the state space technique to avoid the inevitable numerically ill-conditioned problems reported in several literatures. The results obtained via both analytical meth-ods are identical, and a good agreement with their counterparts in literature is observed. The separation-of-variables method can generate exact solutions within 1 s, which is impossible if the state space method is employed. Besides, the combination of the accurate computation method of exponential matrix and the state space method greatly improves the computational efficiency and gives correct results compared with the straightforward use of state space method. 相似文献
102.
可压缩流体恒温热线风速仪校准方法 总被引:1,自引:0,他引:1
开展了恒温(CT)热线风速仪校准方法的研究,以满足可压缩流体中湍流度测量需求。将对数函数与多元回归技术相结合,建立了恒温热线风速仪校准的数学模型,并进行了风洞湍流度测量试验验证。在马赫数Ma=0.3~0.55范围内进行了校准试验,根据建立的数学模型对试验数据进行拟合,拟合优度R2=0.999 82,平均绝对速度偏差Δu=0.18m/s,基本满足了恒温热线风速仪校准精度要求。对马赫数Ma=0.55条件下流场进行了湍流度测量,速度测量偏差为0.034%,流场湍流度Tu=0.14%。试验结果证明了恒温热线风速仪应用于可压缩流体速度测量的可行性。 相似文献
103.
104.
Li-xue Zou Shao-yan CuiJian Zhong Zong-chun YiYan Sun Yu-bo FanFeng-yuan Zhuang 《Advances in Space Research (includes Cospar's Information Bulletin, Space Research Today)》2010
Hematopoietic progenitor cell proliferation can be alternated on either spaceflight or under simulated microgravity experiments on the ground; however, the underlying mechanism remains largely unknown. In the present study, we have demonstrated that exposure of human erythropoietin (EPO)-dependent leukemia cell line UT-7/EPO cells to conditions of simulated microgravity with a rotary culture instrument significantly inhibited the cellular proliferation rate. Adding higher concentrations of EPO to the culture medium failed to improve the inhibitory status. Cell apoptosis was detected by fluorescence staining of cell nuclei and a flow cytometry assay using Annexin V/PI double staining. This microgravity-induced apoptosis in UT-7/EPO cells could be blocked by a pancaspase inhibitor Z-VAD-FMK. Immunoblotting demonstrated that rotary culture resulted in a reduction of the expression of Bcl-xL, an anti-apoptotic protein, and the cleavage of caspase-3. Furthermore, rotary culture reduced surface localization and protein content, as well as the mRNA expression of erythropoietin receptor (EPOR) of UT-7/EPO. Take together, the findings indicated that simulated microgravity may induce mitochondrial related apoptosis of UT-7/EPO cell through depressing the EPO–EPOR pathway. 相似文献
105.
数字化人体建模技术--Pro/Engimeer Mankin 近日,PTC公司推出的Pro/Engineer Mankin是一款能够使设计团队在3D产品的设计模型中插入3D数字化人体造模解决方案,用以模拟仿真及实现人机互动. 相似文献
106.
Li-xue Zou Shao-yan CuiJian Zhong Zong-chun YiYan Sun Yu-bo FanFeng-yuan Zhuang 《Advances in Space Research (includes Cospar's Information Bulletin, Space Research Today)》2011
Hematopoietic progenitor cell proliferation can be altered in either spaceflight or under simulated microgravity experiments on the ground, however, the underlying mechanism remains unknown. Our previous study showed that exposure of the human erythropoietin (EPO)-dependent leukemia cell line UT-7/EPO to conditions of simulated microgravity significantly inhibited the cellular proliferation rate and induced cell apoptosis. We postulated that the downregulation of the erythropoietin receptor (EPOR) expression in UT-7/EPO cells under simulated microgravity may be a possible reason for microgravity triggered apoptosis. In this paper, a human EPOR gene was transferred into UT-7/EPO cells and the resulting expression of EPOR on the surface of UT-7/EPO cells increased approximately 61% (p < 0.05) as selected by the antibiotic G418. It was also shown through cytometry assays and morphological observations that microgravity-induced apoptosis markedly decreased in these UT-7/EPO–EPOR cells. Thus, we concluded that upregulation of EPOR in UT-7/EPO cells could inhibit the simulated microgravity-induced cell apoptosis in this EPO dependent cell line. 相似文献
107.
108.
行进了可压缩球涡和平面激波相互作用的数值研究。一方面,用非定常Euler方程数值模拟了一种可压缩球涡的自身演化,同时,利用Rankine-Hugoniot关系,在流场中嵌入运动激波,求解了激波-球涡相干的流动过程。 相似文献
109.
研制了三种急冷Al基活性钎料。研究结果表明:急冷Al基活性钎料的组织明显细化,熔点明显下降,基体硬度升高。在较低的钎焊温度(750℃)下,下加Ni粉的接头的剪切强度较高(208.8MPa)。钎焊温度对接头强度影响较大。当超过一定钎焊温度后,接头强度明显下降;加Ni粉复合钎焊可明显提高接头的剪切强度,在钎焊温度为800℃时接头的最高剪切强度为225MPa,加Ni粉的复合接头在界面两侧形成均匀分布富Ni带。这是接头强度提高的主要原因。 相似文献
110.