Early effects of low dose C ion or X-ray irradiation on human peripheral blood lymphocytes

The aim of this study was to estimate the acute effects of low dose ¹²C⁶⁺ ions or X-ray radiation on human immune function. The human peripheral blood lymphocytes (HPBL) of seven healthy donors were exposed to 0.05 Gy ¹²C⁶⁺ ions or X-ray radiation and cell responses were measured at 24 h after exposure. The cytotoxic activities of HPBL were determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT); the percentages of T and NK cells subsets were detected by flow cytometry; mRNA expression of interleukin (IL)-2, tumor necrosis factor (TNF)-α and interferon (IFN)-γ were examined by real time quantitative RT-PCR (qRT-PCR); and these cytokines protein levels in supernatant of cultured cells were assayed by enzyme-linked immunosorbent assays (ELISA). The results showed that the cytotoxic activity of HPBL, mRNA expression of IL-2, IFN-γ and TNF-α in HPBL and their protein levels in supernatant were significantly increased at 24 h after exposure to 0.05 Gy ¹²C⁶⁺ ions radiation and the effects were stronger than observed for X-ray exposure. However, there was no significant change in the percentage of T and NK cells subsets of HPBL. These results suggested that 0.05 Gy high linear energy transfer (LET) ¹²C⁶⁺ radiation was a more effective approach to host immune enhancement than that of low LET X-ray. We conclude that cytokines production might be used as sensitive indicators of acute response to LDI.     

Conceptual design of a bioregenerative life support system containing crops and silkworms

This article summarizes a conceptual design of a bioregenerative life support system for permanent lunar base or planetary exploration. The system consists of seven compartments – higher plants cultivation, animal rearing, human habitation, water recovery, waste treatment, atmosphere management, and storages. Fifteen kinds of crops, such as wheat, rice, soybean, lettuce, and mulberry, were selected as main life support contributors to provide the crew with air, water, and vegetable food. Silkworms fed by crop leaves were designated to produce partial animal nutrition for the crew. Various physical-chemical and biological methods were combined to reclaim wastewater and solid waste. Condensate collected from atmosphere was recycled into potable water through granular activated carbon adsorption, iodine sterilization, and trace element supplementation. All grey water was also purified though multifiltration and ultraviolet sterilization. Plant residue, human excrement, silkworm feces, etc. were decomposed into inorganic substances which were finally absorbed by higher plants. Some meat, ingredients, as well as nitrogen fertilizer were prestored and resupplied periodically. Meanwhile, the same amount and chemical composition of organic waste was dumped to maintain the steady state of the system. A nutritional balanced diet was developed by means of the linear programming method. It could provide 2721 kcal of energy, 375.5 g of carbohydrate, 99.47 g of protein, and 91.19 g of fat per capita per day. Silkworm powder covered 12.54% of total animal protein intakes. The balance of material flows between compartments was described by the system of stoichiometric equations. Basic life support requirements for crews including oxygen, food, potable and hygiene water summed up to 29.68 kg per capita per day. The coefficient of system material closure reached 99.40%.     

HTPBⅠ型裂纹粘弹性有限元分析

在简化模型的基础上，推导了复合固体推进剂中Ⅰ型拉伸裂纹的裂尖区域应力、应变与位移的关系式，并进行了粘弹性有限元方法分析。结果表明，有限元分析能获得具一定精度的结果，并与理论分析基本吻合。     

伪随机脉位调制与单极性伪码调相复合体制引信

伪码调相引信抗干扰能力较差，伪随机脉位调制与单极性伪码调相复合引信是伪码复合体制引信发展的一个重要方向，有必要对该体制引信进行研究。首先给出了伪随机脉位调制与单极性伪码调相复合引信的数学模型，得出了相应的模糊函数、绘制了模糊图的中心部分，接着设计了基于FPGA／CPLD的系统实现原理框图，论证了单极性伪码应用及二次混频法抑制多普勒频率两个关键技术的可行性，并简单介绍了数字相关的思想及其实施。研究表明，该体制引信有良好的整体性能和现实的工程应用前景。     

高速气体离心旋转设备转速测量系统的研究与实现

论文深入分析传统的转速测量方法后,提出了高转速多频转速测量算法,实现高转速状态下的快速精确测量,解决了常规转速测量系统无法在较宽范围内取得较高测量精度的问题.利用所提出的软硬件方案,在0～1600r/s 的转速范围内,测量精度可达0.1%.     

航天器测试语言及其运行平台研究

针对测试序列自动执行程度低影响航天器测试效率的问题,提出了一种可控制流程的 高级语言形式的新型航天器测试语言（STL）,并对其语言执行机构进行研究,设计并实现 了基于插件技术的以解释器为核心的集成开发环境——航天器测试语言运行平台。实践表 明航天器测试语言具有较强的通用性与实用性,该语言运行平台能够有效降低航天器地面测 试强度,节约测试成本,提高测试效率。
     

基于浮空器的新型应急通信监测系统

介绍了一种新型的机动式空中应急通信监测系统,该系统以机动式系留气球和小型遥控飞艇为空中平台,搭载各种通信、侦察、监测等电子设备,具有快速灵活、机动性强、费用低廉等特点,能够适应复杂环境,面对突发事件时可以快速布置到任何需要的地方。     

柔性多体撞击系统的精细H∞控制研究

本文在柔性多体撞击系统动力学方程的基础上 ,将撞击看成是一种扰动 ,设计了一个稳定的控制器以使撞击扰动对控制输出的影响达到最小的目的 ,在分析过程中采用 H∞ 控制原理对该问题进行了研究。在计算中 ,将精细积分法应用于状态动力学方程和 Riccati方程的求解中 ,使计算精度得到大幅度提高。最后通过数值例题说明了本文方法的有效性     

截断分布下广义失效概率的可靠性分析方法

提出基于随机变量为截断分布和失效域模糊下的结构可靠性分析方法。由于常规的可靠性分析方法不能直接用于截断分布情况下广义失效概率的计算,因此,先将截断分布情况下的可靠性分析模型转化为非截断分布情况下的多模式并联系统模型,在此基础上引入模糊失效域的隶属函数,将截断分布情况下的模糊可靠性分析问题转化为一般的随机可靠性问题,利用Monte Carlo法和重要抽样法求得广义失效概率。给出了方法的实现步骤和原理,并用不同算例验证了方法的合理性与可行性。