硝胺固体推进剂燃烧性能计算的神经网络方法

传统的燃烧模型致力于对固体推进剂燃烧的物理化学过程的数学描述，其发展往往受到对推进剂燃烧机理认识程度的限制，本文利用误差反转（ＢＰ）神经网络建模的方法建立了硝胺固体推进剂燃烧性能及其影响因素（硝胺含量、压强、硝胺重均粒径）的定量关系，而不考虑燃烧的具体过程，根据此定量关系对硝胺固体推进剂燃烧性能的计算表明，计算结果和实验值吻合得较好，这为推进剂配方的计算机辅助设计提供了一种新方法。     

Simulated microgravity induce apoptosis and down-regulation of erythropoietin receptor of UT-7/EPO cells

Hematopoietic progenitor cell proliferation can be alternated on either spaceflight or under simulated microgravity experiments on the ground; however, the underlying mechanism remains largely unknown. In the present study, we have demonstrated that exposure of human erythropoietin (EPO)-dependent leukemia cell line UT-7/EPO cells to conditions of simulated microgravity with a rotary culture instrument significantly inhibited the cellular proliferation rate. Adding higher concentrations of EPO to the culture medium failed to improve the inhibitory status. Cell apoptosis was detected by fluorescence staining of cell nuclei and a flow cytometry assay using Annexin V/PI double staining. This microgravity-induced apoptosis in UT-7/EPO cells could be blocked by a pancaspase inhibitor Z-VAD-FMK. Immunoblotting demonstrated that rotary culture resulted in a reduction of the expression of Bcl-xL, an anti-apoptotic protein, and the cleavage of caspase-3. Furthermore, rotary culture reduced surface localization and protein content, as well as the mRNA expression of erythropoietin receptor (EPOR) of UT-7/EPO. Take together, the findings indicated that simulated microgravity may induce mitochondrial related apoptosis of UT-7/EPO cell through depressing the EPO–EPOR pathway.     

多核处理器P2020的访存实时性分析与优化

多核处理器以其高集成度、高性能功耗比的特点，获得了军事、电信、网络等领域的关注，但多个处理核心对共享资源的抢占带来的实时性问题阻碍了多核处理器在上述领域的应用。面向实时性的代表指标———访存时间，以P2020为研究对象，分析了其实时性的影响因素，采用可变步长的模型，对各种影响因素进行了定量的测试与分析，为多核处理器访存实时性的优化提供了参考。     

PTC推出优化人机交互的Pro/Engineer Mankin

数字化人体建模技术--Pro/Engimeer Mankin 近日,PTC公司推出的Pro/Engineer Mankin是一款能够使设计团队在3D产品的设计模型中插入3D数字化人体造模解决方案,用以模拟仿真及实现人机互动.     

Upregulation of erythropoietin receptor in UT-7/EPO cells inhibits simulated microgravity-induced cell apoptosis

Hematopoietic progenitor cell proliferation can be altered in either spaceflight or under simulated microgravity experiments on the ground, however, the underlying mechanism remains unknown. Our previous study showed that exposure of the human erythropoietin (EPO)-dependent leukemia cell line UT-7/EPO to conditions of simulated microgravity significantly inhibited the cellular proliferation rate and induced cell apoptosis. We postulated that the downregulation of the erythropoietin receptor (EPOR) expression in UT-7/EPO cells under simulated microgravity may be a possible reason for microgravity triggered apoptosis. In this paper, a human EPOR gene was transferred into UT-7/EPO cells and the resulting expression of EPOR on the surface of UT-7/EPO cells increased approximately 61% (p < 0.05) as selected by the antibiotic G418. It was also shown through cytometry assays and morphological observations that microgravity-induced apoptosis markedly decreased in these UT-7/EPO–EPOR cells. Thus, we concluded that upregulation of EPOR in UT-7/EPO cells could inhibit the simulated microgravity-induced cell apoptosis in this EPO dependent cell line.     

可压缩球涡和平面激波相互作用的数值研究

行进了可压缩球涡和平面激波相互作用的数值研究。一方面，用非定常Ｅｕｌｅｒ方程数值模拟了一种可压缩球涡的自身演化，同时，利用Ｒａｎｋｉｎｅ－Ｈｕｇｏｎｉｏｔ关系，在流场中嵌入运动激波，求解了激波－球涡相干的流动过程。     

用急冷Al基活性钎料钎焊Si3N4陶瓷的研究

研制了三种急冷Ａｌ基活性钎料。研究结果表明：急冷Ａｌ基活性钎料的组织明显细化，熔点明显下降，基体硬度升高。在较低的钎焊温度（７５０℃）下，下加Ｎｉ粉的接头的剪切强度较高（２０８．８ＭＰａ）。钎焊温度对接头强度影响较大。当超过一定钎焊温度后，接头强度明显下降；加Ｎｉ粉复合钎焊可明显提高接头的剪切强度，在钎焊温度为８００℃时接头的最高剪切强度为２２５ＭＰａ，加Ｎｉ粉的复合接头在界面两侧形成均匀分布富Ｎｉ带。这是接头强度提高的主要原因。     

弹射救生用人体数学模型

 利用人体弹射试验数据建立起人体动力学特性的数学模型(简称人体数学模型)。模型的动态响应特性分析可以解决一些与弹射有关的人体工程学问题。根据人体的最大动态超调,结合椎骨强度可确定人体耐受弹射加速度的限度。从防护角度出发,分析座垫对人体受力的影响和人体响应的时相特点而要求座垫厚度必需很薄。还提出改善弹射动力和确定测试系统性能指标的依据。将模型用于弹射实践可以减少人体试验,对人体安全和研制生产都极其有利。     

高压自燃双组元液体火箭发动机燃烧模型

本文提出了一个高压自燃双组元液体火箭发动机稳态燃烧计算模型.文中报告了特种发动机燃烧室压力、混合比、推进剂喷注温度和喷注器结构对燃烧过程影响的计算及分析结果.各种参数影响规律与实际发动机试验结果符合很好.     

有隔板和无隔板的液体火箭发动机冷态全流场数值模拟

针对液体火箭发动机燃烧室内有隔板和无隔板的情况，用数值模拟的方法对发动机冷态全流场进行了计算，探讨了燃烧室内有隔板时边界条件的处理、计算区域的离散以及隔板对流场参数的影响等问题，用欧拉坐标系下的Navier－Stokes方程组描述气相控制方程，通过数值模拟成功地对燃烧室内有隔板和无隔板的流场进行了数值仿真，表明了对隔板体的数值处理方法的可行性。