Fluid electrolyte excretion during different hypokinetic body positions of trained subjects

The aim of this study was to evaluate the effect of different body positions on renal excretion of fluid and electrolytes after exposure to 364 days of decreased number of steps per day (hypokinesia, HK). The studies were performed on 18 endurance trained male volunteers aged 19-24 years who had an average of VO2max 67 ml/kg body/min. All volunteers were divided into three equal groups: the 1st group subjected to 12 h orthostatic position (OP) and 12 h clinostatic position (CP)/day, the 2nd group exposed to 8 h orthostatic position and 14 h clinostatic position/day, and the 3rd group submitted to 10 h orthostatic position and 16 h clinostatic position/day for 364 days. For the simulation of the hypokinetic effect all volunteers were kept under an average of 3000 steps/day for 364 days. Diuresis and the concentrations of sodium, potassium, chloride, calcium and magnesium as well as excretion of creatine were determined in 24-h urine samples. By the end of the hypokinetic period all volunteers, regardless of their body position during HK, manifested a significant increase in renal excretion of fluid and electrolytes as compared to prehypokinetic period values. It was concluded that prolonged restriction of motor activity induced a significant increase in renal excretion of fluid and electrolytes in endurance trained subjects regardless to their body position and duration thereof per day.     

Method of the HF wave absorption evaluation based on GIRO network data

High frequency (HF) communication is strongly dependent on the state of the ionosphere, which specifies the mode structure of the radio wave propagating in ionosphere. Another core factor defining the strength of the HF signal at the receiving site is the ionospheric absorption. Accurate modelling the effect of absorption is an essential part of many studies of the HF propagation in the ionosphere.This paper proposes a method for estimating the absorption. The method is based on analysis of vertical sounding ionograms. The main idea of the approach is to compare the main parameters retrieved from measured and simulated ionograms. The combination of Global Ionospheric Radio Observatory (GIRO, http://giro.uml.edu) data and ionograms modelling allows for developing the empiric absorption model available at near real-time. The ionogram simulation taking into account absorption utilizes the NIM-RT (North Ionospheric Model and Ray Tracing) software. As a result, the proposed technique provides more reliable and accurate evaluation of minimum frequency at which echoes are observed in vertical incidence ionosonde soundings. The values of these frequencies should be used in the following simulation to optimize parameters in the empirical formulae for defining absorption HF wave in ionosphere.The ultimate objective of this work is the designing the method, which allows the simulating of HF radio channel accounting for regular absorption due to UV radiation of the Sun. Eventually it could be considered as some kind of the HF propagation forecasting.     

REMS: The Environmental Sensor Suite for the Mars Science Laboratory Rover

The Rover Environmental Monitoring Station (REMS) will investigate environmental factors directly tied to current habitability at the Martian surface during the Mars Science Laboratory (MSL) mission. Three major habitability factors are addressed by REMS: the thermal environment, ultraviolet irradiation, and water cycling. The thermal environment is determined by a mixture of processes, chief amongst these being the meteorological. Accordingly, the REMS sensors have been designed to record air and ground temperatures, pressure, relative humidity, wind speed in the horizontal and vertical directions, as well as ultraviolet radiation in different bands. These sensors are distributed over the rover in four places: two booms located on the MSL Remote Sensing Mast, the ultraviolet sensor on the rover deck, and the pressure sensor inside the rover body. Typical daily REMS observations will collect 180 minutes of data from all sensors simultaneously (arranged in 5 minute hourly samples plus 60 additional minutes taken at times to be decided during the course of the mission). REMS will add significantly to the environmental record collected by prior missions through the range of simultaneous observations including water vapor; the ability to take measurements routinely through the night; the intended minimum of one Martian year of observations; and the first measurement of surface UV irradiation. In this paper, we describe the scientific potential of REMS measurements and describe in detail the sensors that constitute REMS and the calibration procedures.     

EXPOSE-E: an ESA astrobiology mission 1.5 years in space

The multi-user facility EXPOSE-E was designed by the European Space Agency to enable astrobiology research in space (low-Earth orbit). On 7 February 2008, EXPOSE-E was carried to the International Space Station (ISS) on the European Technology Exposure Facility (EuTEF) platform in the cargo bay of Space Shuttle STS-122 Atlantis. The facility was installed at the starboard cone of the Columbus module by extravehicular activity, where it remained in space for 1.5 years. EXPOSE-E was returned to Earth with STS-128 Discovery on 12 September 2009 for subsequent sample analysis. EXPOSE-E provided accommodation in three exposure trays for a variety of astrobiological test samples that were exposed to selected space conditions: either to space vacuum, solar electromagnetic radiation at >110?nm and cosmic radiation (trays 1 and 3) or to simulated martian surface conditions (tray 2). Data on UV radiation, cosmic radiation, and temperature were measured every 10?s and downlinked by telemetry. A parallel mission ground reference (MGR) experiment was performed on ground with a parallel set of hardware and samples under simulated space conditions. EXPOSE-E performed a successful 1.5-year mission in space.     

An update about recent developments of the PHITS code

PHITS (Particle and Heavy-Ion Transport code System) is a general-purpose three-dimensional Monte Carlo code, developed and maintained by RIST, JAEA and KEK in Japan together with Sihver et al. at Chalmers in Sweden. PHITS can deal with the transports of all varieties of hadrons and heavy ions with energies up to around 100 GeV/nucleon, and in this paper the current status of PHITS is presented. We introduce a relativistically covariant version of JQMD, called R-JQMD, that features an improved ground state initialization algorithm, and we will present the introduction of electron and photon transport in PHITS using EGS5, which have increased the energy region for the photon and energy transport from up to around 3 GeV to up to several hundred GeV depending on the atomic number of the target. We show how the accuracy in dose and fluence calculations can be improved by using tabulated cross sections. Benchmarking of shielding and irradiation effects of high energy protons in different materials relevant for shielding of accelerator facilities is also presented. In particular, we show that PHITS can be used for estimating the dose received by aircrews and personnel in space. In recent years, many countries have issued regulations or recommendations to set annual dose limitations for aircrews. Since estimation of cosmic-ray spectra in the atmosphere is an essential issue for the evaluation of aviation doses, we have calculated these spectra using PHITS. The accuracy of the atmospheric propagation simulation of cosmic-ray performed by PHITS has been well verified by experimental cosmic-ray spectra taken under various conditions. Based on a comprehensive analysis of the simulation results, an analytical model called “PARMA” has been proposed for instantaneously estimating the atmospheric cosmic-ray spectra below the altitude of 20 km. We have also performed preliminary simulations of long-term dose distribution measurements at the ISS performed with the joint ESA-FSA experiment MATROSHKA-R (MTR-R) led by the Russian Federation Institute of Biomedical Problems (IMBP) and the ESA supported experiment MATROSHKA (MTR), led by the German Aerospace Center (DLR). For the purpose of examining the applicability of PHITS to the shielding design in space, the absorbed doses in a tissue equivalent water phantom inside an imaginary space vessel has been estimated for different shielding materials of different thicknesses. The results confirm previous results which indicate that PHITS is a suitable tool when performing shielding design studies of spacecrafts.     

Astrobiology through the ages of Mars: the study of terrestrial analogues to understand the habitability of Mars

Mars has undergone three main climatic stages throughout its geological history, beginning with a water-rich epoch, followed by a cold and semi-arid era, and transitioning into present-day arid and very cold desert conditions. These global climatic eras also represent three different stages of planetary habitability: an early, potentially habitable stage when the basic requisites for life as we know it were present (liquid water and energy); an intermediate extreme stage, when liquid solutions became scarce or very challenging for life; and the most recent stage during which conditions on the surface have been largely uninhabitable, except perhaps in some isolated niches. Our understanding of the evolution of Mars is now sufficient to assign specific terrestrial environments to each of these periods. Through the study of Mars terrestrial analogues, we have assessed and constrained the habitability conditions for each of these stages, the geochemistry of the surface, and the likelihood for the preservation of organic and inorganic biosignatures. The study of these analog environments provides important information to better understand past and current mission results as well as to support the design and selection of instruments and the planning for future exploratory missions to Mars.     

Evaluation of gravity-dependent membrane potential shift in Paramecium

It is still debated whether or not gravity can stimulate unicellular organisms. This question may be settled by revealing changes in the membrane potential in a manner depending on the gravitational forces imposed on the cell. We estimated the gravity-dependent membrane potential shift to be about 1 mV G⁻¹ for Paramecium showing gravikinesis at 1–5 G, on the basis of measurements of gravity-induced changes in active propulsion and those of propulsive velocity in solutions, in which the membrane potential has been measured electrophysiologically. The shift in membrane potential to this extent may occur from mechanoreceptive changes in K⁺ or Ca²⁺ conductance by about 1% and might be at the limit of electrophysiological measurement using membrane potential-sensitive dyes. Our measurements of propulsive velocity vs membrane potential also suggested that the reported propulsive force of Paramecium measured in a solution of graded densities with the aid of a video centrifuge microscope at 350 G was 11 times as large as that for −29 mV, i.e., the resting membrane potential at [K⁺]_o = 1 mM and [Ca²⁺]_o = 1 mM, and, by extrapolation, that Paramecium was hyperpolarized to −60 mV by gravity stimulation of 100- G equivalent, the value corrected by considering the reduction of density difference between the interior and exterior of the cell in the graded density solution. The estimated shift of the membrane potential from −29 mV to −60 mV by 100- G equivalent stimulation, i.e., 0.3 mV G⁻¹, could reach the magnitude entirely feasible to be measured more directly.     

Comparison of various periodograms for sinusoid detection andfrequency estimation

With the advent of the fast Fourier transform (FFT) algorithm, the periodogram and its variants such as the Bartlett's procedure and Welch method, have become very popular for spectral analysis. However, there has not been a thorough comparison of the detection and estimation performances of these methods. Different forms of the periodogram are studied here for single real tone detection and frequency estimation in the presence of white Gaussian noise. The threshold effect in frequency estimation, that is, when the estimation errors become several orders of magnitude greater than the Cramer-Rao lower bound (CRLB), is also investigated. It is shown that the standard periodogram gives the optimum detection performance for a pure tone while the Welch method is the best detector when there is phase instability in the sinusoid. As expected, since the conventional periodogram is a maximum likelihood estimator of frequency, it generally provides the minimum mean square frequency estimation errors     

Dynamically adaptable m-best 2-D assignment algorithm andmultilevel parallelization

In recent years, there has been considerable interest within the tracking community in an approach to data association based on the m-best two-dimensional (2D) assignment algorithm. Much of the interest has been spurred by its ability to provide various efficient data association solutions, including joint probabilistic data association (JPDA) and multiple hypothesis tracking (MHT). The focus of this work is to describe several recent improvements to the m-best 2D assignment algorithm. One improvement is to utilize a nonintrusive 2D assignment algorithm switching mechanism, based on a problem sparsity threshold. Dynamic switching between two different 2D assignment algorithms, highly suited for sparse and dense problems, respectively, enables more efficient solutions to the numerous 2D assignment problems generated in the m-best 2D assignment framework. Another improvement is to utilize a multilevel parallelization enabling many independent and highly parallelizable tasks to be executed concurrently, including 1) solving the multiple 2D assignment problems via a parallelization of the m-best partitioning task, and 2) calculating the numerous gating tests, state estimates, covariance calculations, and likelihood function evaluations (used as cost coefficients in the 2D assignment problem) via a parallelization of the data association interface task. Using both simulated data and an air traffic surveillance (ATS) problem based on data from two Federal Aviation Administration (FAA) air traffic control radars, we demonstrate that efficient solutions to the data association problem are obtainable using our improvements in the m-best 2D assignment algorithm     

The Solar Origin of Corotating Interaction Regions and Their Formation in the Inner Heliosphere

Corotating Interaction Regions (CIRs) form as a consequence of the compression of the solar wind at the interface between fast speed streams and slow streams. Dynamic interaction of solar wind streams is a general feature of the heliospheric medium; when the sources of the solar wind streams are relatively stable, the interaction regions form a pattern which corotates with the Sun. The regions of origin of the high speed solar wind streams have been clearly identified as the coronal holes with their open magnetic field structures. The origin of the slow speed solar wind is less clear; slow streams may well originate from a range of coronal configurations adjacent to, or above magnetically closed structures. This article addresses the coronal origin of the stable pattern of solar wind streams which leads to the formation of CIRs. In particular, coronal models based on photospheric measurements are reviewed; we also examine the observations of kinematic and compositional solar wind features at 1 AU, their appearance in the stream interfaces (SIs) of CIRs, and their relationship to the structure of the solar surface and the inner corona; finally we summarise the Helios observations in the inner heliosphere of CIRs and their precursors to give a link between the optical observations on their solar origin and the in-situ plasma observations at 1 AU after their formation. The most important question that remains to be answered concerning the solar origin of CIRs is related to the origin and morphology of the slow solar wind. This revised version was published online in August 2006 with corrections to the Cover Date.