X-ray induced alterations in the differentiation and mineralization potential of murine preosteoblastic cells

To evaluate the effects of ionizing radiation (IR) on murine preosteoblastic cell differentiation, we directed OCT-1 cells to the osteoblastic lineage by treatment with a combination of β-glycerophosphate (β-GP), ascorbic acid (AA), and dexamethasone (Dex). In vitro mineralization was evaluated based on histochemical staining and quantification of the hydroxyapatite content of the extracellular bone matrix. Expression of mRNA encoding Runx2, transforming growth factor β1 (TGF-β1), osteocalcin (OCN), and p21^CDKN1A was analyzed. Exposure to IR reduced the growth rate and diminished cell survival of OCT-1 cells under standard conditions. Notably, calcium content analysis revealed that deposition of mineralized matrix increased significantly under osteogenic conditions after X-ray exposure in a time-dependent manner. In this study, higher radiation doses exert significant overall effects on TGF-β1, OCN, and p21^CDKN1A gene expression, suggesting that gene expression following X-ray treatment is affected in a dose-dependent manner. Additionally, we verified that Runx2 was suppressed within 24 h after irradiation at 2 and 4 Gy. Although further studies are required to verify the molecular mechanism, our observations strongly suggest that treatment with IR markedly alters the differentiation and mineralization process of preosteoblastic cells.     

Training effectiveness evaluation of helicopter emergency relief based on virtual simulation

Helicopters are playing an increasingly important part in emergency relief, such as earthquake rescue, firefighting and medical transport. With the development of virtual simulation technology, virtual simulation-based training is widely used in the training of the helicopter crew especially for the dangerous and costly missions mentioned above. A complete training effectiveness evaluation method is proposed to evaluate the trainees’ training effect based on virtual simulation in this paper. A key to this method is regarding the complicated process as a discrete event-activity flow system and establishing the evaluation indicator system. Then expert group and Analytical Network Process (ANP) are applied to determine the weight of indicators. When the training data are processed, there is a novel attempt to apply Fuzzy Comprehensive Evaluation (FCE) model to calculate the two categories of indicators. Eventually, an experiment and the analysis were carried out to validate the evaluation method.     

3-D position estimation of isolated target and optimal trajectory choice in parasitic synthetic aperture radar

Bistatic SAR (BSAR) systems have recently been the subject of several studies, but little attention has been given to the potential of the location of targets. In the paper, the performance of the estimation of 3-D position of a target (TPE) in parasitic SAR is obtained analytically and illustrated by computer simulation using ambiguity function analysis, and the maximum likelihood estimate (MLE) approach. It was shown that by using a multi look parasitic BSAR all three coordinates of an isolated point target (IPT) could be evaluated. Analytical closed form equations that characterize the measurement accuracy were derived. In the final these equations will be used to demonstrate various cases of more practical, including optimal trajectories choice under any geometry configuration case, moreover, the conclusion is verified via Matlab.     

新型磁性液体材料的研究与探讨

磁性液体，是由固体的磁性粒子分散到载体（液体）中形成的一种胶体溶液，此种深夜既有液体的流动性，又具有磁性，是一种新型的磁性材料，本文对磁性液体的制造方法，及其存在的条件，进行了研究与探讨，并简单介绍了磁性液体的性质及其应用前景。     

SEQUENTIAL ALGORITHM FOR MULTISENSOR PROBABILISTIC DATA ASSOCIATION

Jointprobabillsticdataassociation(JPDA)isanalgorithmusedinsinglesensormultipletargettrackingsystems.Itemploysthenon-uniqueassignmentof"allneighbor"strategytoadaptforthedensemultitargettrackingenvironments[1].Becauseofitswideapplications,itisnecessarytoextendJPDAintosomemultiplesensortrackingsystems.Suchamultisensorsystem,forexample,canbeformedbycollocatingradarandinfraredsearchandtrack(IRST)whichcantakeadvantagesofboththesensorsbodatafusion.Undertheconditionofthesamesensors,acommonmeasure…     

高效离子电热水器的设计

描述一种由AT89C2051单片机控制的高效离子电热水器，该热水器使用安全，即开即热，转换效率高。     

VERICUT数控程序切削速度优化

优化原理来源于实际生产.无论是手工编程还是软件编程,其程序速度一般比较固定,可以给定例如下刀、抬刀速度,但无法得知每步的切削量,从而无法根据切削量调整切削速度,所以我们在实际生成中常常看到机床操作者使用倍率旋钮来调整切削速度,操作者的目的是:第一,避免切削余量大,损坏刀具和损伤机床;第二,提高加工效率.     

为树脂转移注射工艺开发的新型PMI泡沫

因为加工的原因,即使100%的闭孔泡沫芯材在表面也有开孔,这在RTM注射过程中,树脂会浸入,导致夹层结构部件的总重量增加,而这是我们所不希望看到的.针对这个问题,本文主要介绍了2种针对RTM工艺特别开发的新型ROHACELL泡沫.     

一种基于粗糙K-均值的椭球基函数神经网络

改进了一种椭球基函数神经网络,它与经典椭球单元神经网络的结构不同,而与径向基函数神经网络结构类似,即它有一个隐含层,并且隐层单元采用椭球基函数,区别于RBF网络的高斯函数。本文采用粗糙K-均值方法求取椭球函数的中心,并给出了该方法中确定初始阈值的步骤。这种改进方法不但使对输入空间的划分局部作用,而且划分区域封闭有界。因此,改进的神经网络具有较好的函数逼近能力和模式识别能力。仿真实验验证了该椭球基函数神经网络的正确性和有效性。     

圆锥形薄壁壳体的弹性稳定性

基于Donnell型扁壳理论,利用法分析了在均布外压作用下圆锥形薄壁壳体的弹性稳定性问题。根据外压实验观察结果和通过选取适当的位移分量表达式,文中给出了临界外压的近似表达式。数值结果表明,本文理论分析预示值与临界载荷的实验值很吻合。文中还对有关参数对临界载荷的影响进行了讨论。本文所得结果可供工程应用参考。