Induction of high grade astrocytoma (HGA) by protons: molecular mechanisms and RBE considerations.

Protons of a specific energy, 55 MeV, have been found to induce primary high grade astrocytomas (HGA) in the Rhesus monkey (Macaca mulatta). Brain tumors of this type were not induced by protons of other energies (32-2,300 MeV). Induction of HGA has been identified in human patients who have had radiation therapy to the head. We believe that the induction of HGA in the monkey is a consequence of dose distribution, not some unique "toxic" property of protons. Comparison of the human experience with the monkey data indicates the RBE for induction of brain tumors to be about one. It is unlikely that protons cause an unusual change in oncogenic expression, as compared to conventional electromagnetic radiation.     

On the contribution of space medicine in the public health care

With the beginning of space era, a new branch of medicine has arisen and has been developing along with human exploration of outer space. And even though space medicine mainly faces the same problems as traditional medicine--cosmonauts health care and their high efficiency--this branch, has its own features, associated with the unusual factors of space flight, of which weightlessness is the major one. During the development of manned cosmonautics (duration of a human stay in space has reached already 438 days), methods of cosmonauts medical support and monitoring of their condition have been developed, knowledge of human possibilities and methods of process of organism adaptation to various and frequently severe conditions of external environment have increased. All this led to the fact that nowadays space medicine can become useful for improvement of human health care not only in space but also on the Earth. Moreover, the problem of implementation of cosmonautics achievements, and in particular of space medicine, in practice of public health care presents one of the most important issues concerning human health care. It is also connected with public opinion which is more and more concerned about the efficiency of significant expenses on space activities, especially lately. People often are set by the questions: what has space given, what fruits has space research provided to mankind, which results of this research can be used on the Earth already today for improvement of their life, for discussion of many difficult earthly problems? In terms of using cosmonautics possibilities, its achievements for health care and treatment, it is possible to define a few branches, in which purposeful studies are carried out.     

Influence of graviceptives cues at different level of visual information processing: the effect of prolonged weightlessness

We evaluated the influence of prolonged weightlessness on the performance of visual tasks in the course of the Russian-French missions ANTARES, Post-ANTARES and ALTAIR aboard the MIR station. Eight cosmonauts were subjects in two experiments executed pre-flight, in-flight and post-flight sessions.

In the first experiment, cosmonauts performed a task of symmetry detection in 2-D polygons. The results indicate that this detection is locked in a head retinal reference frame rather than in an environmentally defined one as meridional orientations of symmetry axis (vertical and horizontal) elicited faster response times than oblique ones. However, in weightlessness the saliency of a retinally vertical axis of symmetry is no longer significantly different from an horizontal axis. In the second experiment, cosmonauts performed a mental rotation task in which they judged whether two 3-D objects presented in different orientations were identical. Performance on this task is basically identical in weightlessness and normal gravity.     

Simulation of a working process in the pulsejet engine with an aerodynamic valve on the basis of the thermodynamic cycle analysis

A physical and a mathematical model of a working process in the pulsejet engine based on the analysis of the thermodynamic cycle are proposed. The process of self-sustained periodic combustion is connected with special features of elementary processes comprising the cycle, influencing the engine operation and depending on its design parameters. The calculation method is based on the use of fundamental laws of conservation and basic equations of gas dynamics     

The Genesis Solar-Wind Collector Materials

Genesis (NASA Discovery Mission #5) is a sample return mission. Collectors comprised of ultra-high purity materials will be exposed to the solar wind and then returned to Earth for laboratory analysis. There is a suite of fifteen types of ultra-pure materials distributed among several locations. Most of the materials are mounted on deployable panels (‘collector arrays’), with some as targets in the focal spot of an electrostatic mirror (the ‘concentrator’). Other materials are strategically placed on the spacecraft as additional targets of opportunity to maximize the area for solar-wind collection. Most of the collection area consists of hexagonal collectors in the arrays; approximately half are silicon, the rest are for solar-wind components not retained and/or not easily measured in silicon. There are a variety of materials both in collector arrays and elsewhere targeted for the analyses of specific solar-wind components. Engineering and science factors drove the selection process. Engineering required testing of physical properties such as the ability to withstand shaking on launch and thermal cycling during deployment. Science constraints included bulk purity, surface and interface cleanliness, retentiveness with respect to individual solar-wind components, and availability. A detailed report of material parameters planned as a resource for choosing materials for study will be published on a Genesis website, and will be updated as additional information is obtained. Some material is already linked to the Genesis plasma data website (genesis.lanl.gov). Genesis should provide a reservoir of materials for allocation to the scientific community throughout the 21st Century. This revised version was published online in August 2006 with corrections to the Cover Date.     

Eruptive prominences as sources of magnetic clouds in the solar wind

Large amounts of coronal material are propelled outward into interplanetary space by Coronal Mass Ejections (CMEs). Thus one might expect to find evidence for expanding flux ropes in the solar wind as well. To prove this assumption magnetic clouds were analyzed and correlated with H-observations of disappearing filaments. When clouds were found to be directly associated with a disappearing filament, the magnetic structure of the cloud was compared with that of the associated filament. Additionally the expansion of magnetic clouds was examined over a wide range of the heliosphere and compared with the expansion observed for erupting prominences.     

Geomagnetic micropulsations and diagnostics of the magnetosphere

Plasma oscillations in a wide range of spectrum exist in the magnetosphere. Part of them penetrate the ionosphere and are recorded on the earth's surface. In the range of frequencies from millihertz to several hertz, the so-called micropulsations (ULF) are observed. In the range from hundred of hertz to several kilohertz the low-frequency emissions (VLF) are registered. Both types of emissions contain interesting and important information on the physical parameters of the magnetosphere and on the processes developing in it. The following paper describes the main problems of the diagnostics of the magnetosphere, which are based on the surface observations of micropulsations.In the first part of the paper, a short summary of theoretical conceptions on micropulsations is given. The main part of the paper describes the methods of diagnostics of the location of the boundary of the magnetosphere, of cold-plasma concentration in the outer regions of the magnetosphere, as well as of the energies and fluxes of fast charged particles in the geomagnetic trap. Some experimental results of the diagnostics of the parameters of the magnetosphere are given. Advantages and deficiencies of the existing methods of surface diagnostics are discussed, and the directions of further investigations are traced.     

On-Line Computer for Transient Turbine Cascade Instrumentation

A 32-channel computer based data acquisition and processing system em has been developed for use with the new type of transient cascade facility at Oxford. This is used for testing turbine blades and nozzle guide vanes at full-scale engine Reynolds and Mach numbers ers with correct wallto-flow temperature ratios. A novel technique for processing transient heat transfer data from thin film surface resistance thermometers has been developed. Measurements of surface ace pressure around blades, and of the upstream turbulence level have been made. The cascade and instrumentation are shown to have advantages both in cost and effectiveness over continuous running cascades.     

Observational Manifestation of Chaos in the Gaseous Disk of the Grand Design Spiral Galaxy NGC 3631

The main goal of the paper is to demonstrate the presence of chaotic trajectories in the gaseous disk of a real spiral galaxy. As an example we have chosen NGC 3631. First, we show the stationarity of the 3-D velocity field restored from the observed line-of-sight velocity field of the gaseous disk. That allows to analyse behaviour of the trajectories of the fluid particles (gas clouds) in the disk, calculating the corresponding observed streamlines. We estimate the Lyapunov characteristic numbers using their independence of the metrics and show the existence of chaotic trajectories outside the vortices which are present in the velocity field, and in the vicinity of the saddle point. Related spectra of the stretching numbers for some trajectories are also calculated.     

Energetics of reconnection: A reply

In this article we address several criticisms of Petschek-type reconnection models which have recently been raised by Heikkila. We discuss features of the time-dependent Petschek-type models in the context of the solar wind-magnetosphere interaction, and point out that such models can incorporate and reproduce observed features at the magnetopause, such as plasma jets and erosion of the current sheet. We argue that some of Heikkila's criticisms can be attributed to weaknesses in the analysis due to incomplete experimental information, rather than to flaws in the concept of reconnection per se; in this category we include the question of which instability leads to the localised breakup of the magnetopause current sheet. Other criticisms are based on an adherence to steady-state models, and cannot be sustained within the extended time-dependent theory. We discuss, for example, how the time-dependent model can provide a consistent picture of how energy from the incoming solar wind is transferred and converted as it enters the magnetosphere.