Planetary Atmospheres

The predominance of nitrogen in highly volatile forms and of carbon in solids set the abundance ratios of these elements in the inner planets, meteorites and comets. The absence of carbon compounds in an atmosphere then signals large deposits of carbon-bearing compounds in surface and/or subsurface deposits. In contrast, the icy planetesimals that contributed heavy elements to Jupiter must have had identical enrichments (relative to hydrogen) of both C and N, as well as other heavy elements that have been measured, compared to solar values. Capture of N and Ar suggests that the icy planetesimals that carried these elements must have formed at low temperatures, <40 K. New measurements of isotopes of nitrogen support this picture, but we must have more measurements in more atmospheres to be certain of this scenario.     

The Solar Dynamo: The Role of Penetration, Rotation and Shear on Convective Dynamos

In this paper I discuss the importance of turbulence, rotation, penetration and shear for solar dynamos (both local and global). An understanding of these processes is vital for progress towards a self-consistent theory for the generation of solar magnetic activity. I discuss the difficulties for large-scale field generation and suggest that large-scale solar magnetic activity may be driven by dynamos that arise owing to instabilities, with these dynamos modified by the presence of turbulence.     

Repair and misrepair of heavy-ion-induced chromosomal damage.

The premature chromosome condensation (PCC) technique was used to investigate chromosomal damage, repair, and misrepair in the G phase of a human/hamster hybrid cell line that contains a single human chromosome. Plateau-phase cell cultures were exposed to either x-rays or a 425 MeV/u beam of neon ions near the Bragg peak where the LET is 183 kev/micrometers. An in situ hybridization technique coupled to fluorescent staining of PCC spreads confirmed the linearity of the dose response for initial chromatin breakage in the human chromosome to high doses (1600 cGy x-ray or 1062 cGy Ne). On Giemsa-stained slides, initial chromatin breakage in the total genome and the rejoining kinetics of these breaks were determined. As a measure of chromosomal misrepair, ring PCC aberrations were also scored. Ne ions were about 1.5 x more effective per unit dose compared to x-rays at producing the initially measured chromatin breakage. 90% of the x-ray-induced breaks rejoined in cells incubated at 37 degrees C after exposure. In contrast, only 50% of Ne-ion-induced breaks rejoined. In the irradiated G1 cells, ring PCC aberrations increased with time apparently by first order kinetics after either x-ray or Ne exposures. However, far fewer rings formed in Ne-irradiated cells after a dose giving a comparable initial number of chromatin breaks. Following x-ray exposures, the yield of rings formed after long repair times (6 to 9 hrs) fit a quadratic dose-response curve. These results indicate quantitative and qualitative differences in the chromosomal lesions induced by low- and high-LET radiations.     

Neoplastic cell transformation by energetic heavy ions and its modification with chemical agents.

For many years we have been interested in understanding the potential carcinogenic effects of cosmic rays. We have studied the oncogenic effects of cosmic rays with accelerator-produced heavy particle radiation and with a cultured mammalian cell system--C3H10T1/2 cells. Our quantitative data obtained with carbon, neon, silicon, and iron particles showed that RBE is both dose and LET dependent for neoplastic cell transformation. RBE is higher at lower dose, and RBE increases with LET up to about 200 keV/micrometer. In nonproliferation confluent cells, heavy-ion induced transformation damage may not be repairable, although a dose modifying factor of about 1.7 was observed for X-ray radiation. Our recent studies with super-heavy high-energy particles, e.g., 960 MeV/U U235 ions (LET = 1900 keV/micrometer), indicate that these ions with a high inactivation cross-section can cause neoplastic cell transformation. The induction of cell transformation by radiation can be modified with various chemicals. We have found that the presence of DMSO (either during or many days after irradiation) decreased the transformation frequency significantly. It is, therefore, potentially possible to reduce the oncogenic effect of cosmic rays in space through some chemical protection.     

Chemical evolution on the giant planets and Titan

We summarize the current status of atmospheric chemistry in the atmospheres of the outer solar system with special emphasis on the question of HCN formation on Jupiter, differences between polar and equatorial compositions on Jupiter, the coloration of the Great Red Spot, and the unique environment of Titan.     

HZE effects on mammalian cells.

In track segment experiments cell survival and chromosome aberrations of mammalian cells have been measured for various heavy ion beams between helium and uranium in the energy range between 0.5 and 960 MeV/u, corresponding to a velocity range of 0.03 to 0.87 C, and an LET spectrum from 10 to 15 000 keV/micrometers. At low LET, the cross section (sigma) for cell killing increases with increasing LET and shows a common curve for all ions regardless of the atomic number. This indicates that in this region the track structure of the different ions is of only a minor influence, and it is rather the total energy transfer, which is important for cell killing. At higher LET values, deviations from a common sigma-LET curve can be observed which indicate a saturation effect. The saturation of the lighter ions occurs at lower LET values than for the heavier ions. These findings are also confirmed by the chromosome data, where the efficiency for the induction of chromosomal aberrations for high LET particles depends on the track structure and is nearly independent of LET. In the heavier beams (Z > or = 10) individual particles cause multiple chromosome breaks in mitotic cells.     

Rapid development of corneal lesions in rats produced by heavy ions.

Scanning electron micrographs of heavy ion irradiated corneas demonstrate a significant correlation with the heavy ion beam: The average number of plasma membrane lesions per unit area of corneal surface is correlated with the particle fluence of the beam. This observation corroborates what has already been suggested theoretically about heavy ion tracks and what has been shown experimentally through etched plastics, developed emulsions, and bubble chambers. But the new data indicate that particle tracks occur in biological tissues as well, and that a single heavy ion is responsible for each membrane lesion.