Anesthesia, surgical aid and resuscitation in manned space missions.

When discussing problems related to medical service in space flight, particular attention should be given to the specific living conditions and changes associated with space flight. In disease and injury, surgery can be provided only after conservative therapy has failed. In this context gnotobiological chambers allowing surgery in aseptic conditions seem promising. A portable set of interchangeable surgical tools should be made of light-weight alloys that can be readily sterilized. Electroanalgesia in combination with auriculoacupuncture as well as peridureal anesthesia may be used as they allow normal operations in autonomous space flight conditions. Changes in the sympatho-adrenal and kallikrein-kinin systems, as well as water-electrolyte balance, should be taken into account in developing methods and means of medical service in critical situations. Special attention should be given to the prevention and treatment of brain edema in view of weightlessness-induced cephalad fluid shifts.     

Shuttle avionics verification and integration testing

The Space Shuttle Orbiter employs a fly-by-wire control system of 200 major avionic hardware devices interfacing with five flight computers through a complex data bus system. Responses to man-in-the-loop commands are dependent on the flight software. Early program development testing of the computer and avionic hardware has been accomplished at Rockwell International's Shuttle Avionics Development Laboratory (ADL). Hardware development has led to complete multi-string system testing and flight software evaluations. This paper provides an overview of the ADL. Its role and test capabilities in support of Shuttle development are defined. The nature of computer driven test programs for the Orbiter displays, the Digital Autopilot, and flight software development describe the test bed provided by the ADL.     

Exobiological exploration of Mars.

Of all the other planets in the solar system, Mars remains the most promising for further elucidating concepts about chemical evolution and the origin of life. Strategies were developed to pursue three exobiological objectives for Mars exploration: determining the abundance and distribution of the biogenic elements and organic compounds, detecting evidence of an ancient biota on Mars, and determining whether indigenous organisms exist anywhere on the planet. The three strategies are quite similar and, in fact, share the same sequence of phases. In the first phase, each requires global reconnaissance and remote sensing by orbiters to select sites of interest for detailed in situ analyses. In the second phase, lander missions are conducted to characterize the chemical and physical properties of the selected sites. The third phase involves conducting "critical" experiments at sites whose properties make them particularly attractive for exobiology. These critical experiments would include, for example, identification of organics, detection of fossils, and detection of extant life. The fourth phase is the detailed analysis of samples returned from these sites in Earth-based laboratories to confirm and extend previous discoveries. Finally, in the fifth phase, human exploration is needed to establish the geological settings for the earlier findings or to discover and explore sites that are not accessible to robotic spacecraft.     

Engineering concepts for inflatable Mars surface greenhouses.

A major challenge of designing a bioregenerative life support system for Mars is the reduction of the mass, volume, power, thermal and crew-time requirements. Structural mass of the greenhouse could be saved by operating the greenhouse at low atmospheric pressure. This paper investigates the feasibility of this concept. The method of equivalent system mass is used to compare greenhouses operated at high atmospheric pressure to greenhouses operated at low pressure for three different lighting methods: natural, artificial and hybrid lighting.     

Automorphogenesis and gravitropism of plant seedlings grown under microgravity conditions.

Plant seedlings exhibit automorphogenesis on clinostats. The occurrence of automorphogenesis was confirmed under microgravity in Space Shuttle STS-95 flight. Rice coleoptiles showed an inclination toward the caryopsis in the basal region and a spontaneous curvature in the same adaxial direction in the elongating region both on a three-dimensional (3-D) clinostat and in space. Both rice roots and Arabidopsis hypocotyls also showed a similar morphology in space and on the 3-D clinostat. In rice coleoptiles, the mechanisms inducing such an automorphic curvature were studied. The faster-expanding convex side of rice coleoptiles showed a higher extensibility of the cell wall than the opposite side. Also, in the convex side, the cell wall thickness was smaller, the turnover of the matrix polysaccharides was more active, and the microtubules oriented more transversely than the concave side, and these differences appear to be causes of the curvature. When rice coleoptiles grown on the 3-D clinostat were placed horizontally, the gravitropic curvature was delayed as compared with control coleoptiles. In clinostatted coleoptiles, the corresponding suppression of the amyloplast development was also observed. Similar results were obtained in Arabidopsis hypocotyls. Thus, the induction of automorphogenesis and a concomitant decrease in graviresponsiveness occurred in plant shoots grown under microgravity conditions.     

A theoretical assessment of the feasibility of potential Lunar Reconnaissance Orbiter radio occultation observations of the lunar ionosphere

The existence of a “dense” lunar ionosphere has been controversial for decades. Positive ions produced from the lunar surface and exosphere are inferred to have densities that are $?$${10}^6$ – ${10}^7$ m^?3 near the surface and smaller at higher altitudes, yet electron densities derived from radio occultation measurements occasionally exceed these values by orders of magnitude. For example, about 4% of the single-spacecraft radio occultation measurements from Kaguya/SELENE were consistent with peak electron densities of $~$$3\times {10}^8$ m^?3. Space plasmas should be neutral on macroscopic scales, so this represents a substantial discrepancy. Aditional observations of electron densities in the lunar ionosphere are critical to resolving this longstanding paradox. Here we theoretically assess whether radio occultation observations using two-way coherent S-band radio signals from the Lunar Reconnaissance Orbiter (LRO) spacecraft could provide useful measurements of electron densities in the lunar ionosphere. We predict the uncertainty in a single LRO radio occultation measurement of electron density to be $~$$3\times {10}^8$ m^?3, comparable to occasional observations by Kaguya/SELENE of a dense lunar ionosphere. Thus an individual profile from LRO is unlikely to reliably detect the lunar ionosphere; however, averages of multiple ($~$10) LRO profiles acquired under similar geophysical and viewing conditions should be able to make reliable detections. An observing rate of six ingress occultations per day ($~$2000 per year) could be achieved with minimal impact on current LRO operations. This rate compares favorably with the 378 observations reported from the single-spacecraft experiment on Kaguya/SELENE between November 2007 and June 2009. The large number of observations possible for LRO would be sufficient to permit wide-ranging investigations of spatial and temporal variations in the poorly understood lunar ionosphere. These findings strengthen efforts to conduct such observations with LRO.     

Planet-B mission to Mars - 1998

PLANET-B is the Japanese Mars orbiter program. The primary objective of the program is to study the Martian aeronomy, putting emphasis on the interaction of the Martian upper atmosphere with the solar wind. The launch of the spacecraft is scheduled for August, 1998. The periapsis altitude and the apoapsis are 150 km and 15 Mars radii, respectively. The dry weight of the orbiter is 186 kg including 14 science instruments. Advanced technologies are employed in the design of the spacecraft in order to overcome the weight limitation. This paper describes the scientific objectives of the PLANET-B program and outline of the spacecraft system.     

Development of data base of the ionosphere disturbances

A properly weighted measure of histogram distortion is proposed to evaluate data with different time scales for any index in any field. This approach is applied to produce a long-term data base of disturbance measure of the geomagnetic indices and ionospheric VI sounding characteristics. It is shown that the ionosphere disturbances detected by the proposed technique include all the storm periods defined by the statistical procedure used earlier at IRPL, NBS, Washington, D.C.     

Surface tension-driven flows in horizontal liquid metal layers

The problem of surface tension-driven flows in horizontal liquid layers has been studied experimentally, and theoretically by direct numerical simulation and small perturbation analysis. We focus our attention on situations in which the depth of the fluid (liquid tin; small Prandtl number, Pr=0.015) is small enough to ensure the predominance of the surface tension forces over those due to the buoyancy. The surface velocity has been experimentally obtained for liquid tin layer with various aspect ratio (length to height) in the range 5<A<83. The thermal gradients are ranged from 5 to 40°K/cm. In the numerical study, the Navier-Stokes and energy equations are solved by an efficient finite difference technique. The parameters governing the flow behaviour in the liquid are varied to determine their effects on thermocapillary convection: the Reynolds number 10<Re<210⁴ and the aspect ratio 2<A<25; with Pr kept constant at Pr=0.015. The linear eigenequation resulting from small spatial disturbances of the Couette flow solution is solved using an Tau-Chebyshev approximation. A notable feature of the theoretical study is the totally different end circulations. In the region near the cold wall a multicell structure is evident. This agrees with the eigensolution which is of complex type, indicating spatial periodicity. In the hot wall region the flow is accelerated to reach the velocity value for the fully-developed Couette flow which is reached under conditions such as Re/A<20. The transition from viscous to boundary layer regime occurs for a critical value (Re/A)_c of nearly about 200, as deduced from the numerical and experimental results.     

The potential of the lichen symbiosis to cope with the extreme conditions of outer space II: germination capacity of lichen ascospores in response to simulated space conditions.

Complementary to the already well-studied microorganisms, lichens, symbiotic organisms of the mycobiont (fungi) and the photobiont (algae), were used as "model systems" in which to examine the ecological potential to resist to extreme environments of outer space. Ascospores (sexual propagules of the mycobiont) of the lichens Fulgensia bracteata, Xanthoria elegans and Xanthoria parietina were exposed to selected space-simulating conditions (up to 16 h of space vacuum at 10(-3) Pa and UV radiation at 160 nm < or = lambda < or = 400 nm), while embedded in the lichen fruiting bodies. After exposure, the ascospores were discharged and their viability was tested as germination capacity on different culture media including those containing Mars regolith simulant. It was found that (i) the germination rate on media containing Mars regolith simulant was as high as on other mineral-containing media, (ii) if enclosed in the ascocarps, the ascospores survived the vacuum exposure, the UV-irradiation as well as the combined treatment of vacuum and UV to a high degree. In general, 50 % or more viable spores were recovered, with ascospores of X. elegans showing the highest survival. It is suggested that ascospores inside the ascocarps are well protected by the anatomical structure, the gelatinous layer and the pigments (parietin and carotene) against the space parameters tested.