Harnessing functional food strategies for the health challenges of space travel—Fermented soy for astronaut nutrition

Astronauts face numerous health challenges during long-duration space missions, including diminished immunity, bone loss and increased risk of radiation-induced carcinogenesis. Changes in the intestinal flora of astronauts may contribute to these problems. Soy-based fermented food products could provide a nutritional strategy to help alleviate these challenges by incorporating beneficial lactic acid bacteria, while reaping the benefits of soy isoflavones. We carried out strain selection for the development of soy ferments, selecting strains of lactic acid bacteria showing the most effective growth and fermentation ability in soy milk (Streptococcus thermophilus ST5, Bifidobacterium longum R0175 and Lactobacillus helveticus R0052). Immunomodulatory bioactivity of selected ferments was assessed using an in vitro challenge system with human intestinal epithelial and macrophage cell lines, and selected ferments show the ability to down-regulate production of the pro-inflammatory cytokine interleukin-8 following challenge with tumour necrosis factor-alpha. The impact of fermentation on vitamin B1 and B6 levels and on isoflavone biotransformation to agluconic forms was also assessed, with strain variation-dependent biotransformation ability detected. Overall this suggests that probiotic bacteria can be successfully utilized to develop soy-based fermented products targeted against health problems associated with long-term space travel.     

Estimating matched filter amplitude probability functions byfailure rate analysis

Performance analysis of echolocation systems requires knowledge of the probability density function (pdf) or cumulative distribution function (cdf) of a matched filter output. A method is presented to estimate these and other probability functions from data by estimating the failure rate function, a function employed in reliability theory. The method can also be used to derive approximations to closed-form probability functions. The method is demonstrated using experimental sonar and radar clutter data and a closed-form radar clutter model     

Identification of Aircraft Stability and Control Parameters Using Hierarchical State Estimation

Previous attempts to identify aircraft stability and control derivatives from flight test data, using three-degrees-of-freedom (3-DOF) longitudinal or lateral-directional perturbation equation-of-motion models, suffer from the disadvantage that the coupling between the longitudinal and lateral-directional dynamics has been ignored. In this paper, the identification of aircraft stability parameters is accomplished using a more accurate 6-DOF model which includes this coupling. Hierarchical system identification theory is used to reduce the computational effort involved. The 6-DOF system of equations is first decomposed into two 3-DOF subsystems, one for the longitudinal dynamics and the other for the lateral-directional dynamics. The two subsystem parameter identification processes are then coordinated in such a way that the overall system parameter identification problem is solved. Next, a six-subsystem decomposition is considered. Computational considerations and comparison with the unhierarchically structured problem are presented.     

Asymptotic theory for thrusting,spinning-up spacecraft maneuvers

We consider the problem of a spacecraft subjected to constant body-fixed forces and moments about all three axes during a spinning-up, thrusting maneuver. In applications, undesired forces and moments can arise due to thruster imbalances and misalignments and to center-of-mass offset. In previous works, approximate analytical solutions have been found for the attitude motion, and for the change in inertial velocity and inertial position. In this paper we find asymptotic and limiting-case expressions which we derive from the analytic solutions, in order to obtain simplified, practical formulas that lend insight into the motion. Specifically, we investigate how the motion evolves (1) as time grows without bound and (2) for geometric cases of the sphere, the thin rod, and the thin plate. Closed-forms or upper-bound limits are provided for angular velocities, Eulerian angles, angular momentum pointing error, transverse and axial velocities, and transverse and axial displacements. Summaries for the asymptotic limits (for zero initial conditions) are provided in tabular form. Results are verified by numerical simulations.     

Prototype design and testing of a Venus long duration,high altitude balloon

This paper describes the design, fabrication and testing of a full scale prototype balloon intended for long duration flight in the upper atmosphere of Venus. The balloon is 5.5 m in diameter and is designed to carry a 45 kg payload at an altitude of 55 km. The balloon material is a 180 g/m² multi-component laminate comprised of the following layers bonded together from outside to inside: aluminized Teflon film, aluminized Mylar film, Vectran fabric and a polyurethane coating. This construction provides the required balloon functional characteristics of low gas permeability, sulfuric acid resistance and high strength for superpressure operation. The design burst superpressure is 39,200 Pa which is predicted to be 3.3 times the worst case value expected during flight at the highest solar irradiance in the mission profile. The prototype is constructed from 16 gores with bi-taped seams employing a sulfuric acid resistant adhesive on the outside. Material coupon tests were performed to evaluate the optical and mechanical characteristics of the laminate. These were followed by full prototype tests for inflation, leakage and sulfuric acid tolerance. The results confirmed the suitability of this balloon design for use at Venus in a long duration mission. The various data are presented and the implications for mission design and operation are discussed.     

Solar modulation model with reentrant particles

We developed a one dimensional model of particle transport in the heliosphere. As opposite to widely used models, we apply a method where a quasi-particle is traced back in time. The model gives us the possibility to work on the possible existence of reentrant particles in the heliosphere that can be hardly solved by the traditional forward tracking method. Particles escape from the heliosphere and may reenter back. We estimate how these particles affect the modulation process in the heliosphere. Presented here are the results for different values of particles mean free path in the interstellar space and for different interstellar magnetic field values.     

“Modular Biospheres” – New testbed platforms for public environmental education and research

This paper will review the potential of a relatively new type of testbed platform for environmental education and research because of the unique advantages resulting from their material closure and separation from the outside environment. These facilities which we term “modular biospheres”, have emerged from research centered on space life support research but offer a wider range of application. Examples of this type of facility include the Bios-3 facility in Russia, the Japanese CEEF (Closed Ecological Experiment Facility), the NASA Kennedy Space Center Breadboard facility, the Biosphere 2 Test Module and the Laboratory Biosphere. Modular biosphere facilities offer unique research and public real-time science education opportunities. Ecosystem behavior can be studied since initial state conditions can be precisely specified and tracked over different ranges of time. With material closure (apart from very small air exchange rate which can be determined), biogeochemical cycles between soil and soil microorganisms, water, plants, and atmosphere can be studied in detail. Such studies offer a major advance from studies conducted with phytotrons which because of their small size, limit the number of organisms to a very small number, and which crucially do not have a high degree of atmospheric, water and overall material closure. Modular biospheres take advantage of the unique properties of closure, as representing a distinct system “metabolism” and therefore are essentially a “mini-world”. Though relatively large in comparison with most phytotrons and ecological microcosms, which are now standard research and educational tools, modular biospheres are small enough that they can be economically reconfigured to reflect a changing research agenda. Some design elements include lighting via electric lights and/or sunlight, hydroponic or soil substrate for plants, opaque or glazed structures, and variable volume chambers or other methods to handle atmospheric pressure differences between the facility and the outside environment.     

Photolytic behaviour of methane at Lyman-α and 248 nm: Studies in the frame of a simulation program of Titan’s atmosphere (S.E.T.U.P.)

This paper first describes briefly some of the forefront global simulations of Titan’s atmosphere that have been carried out up to now. In these experiments, an initial gaseous mixture of N₂/CH₄ is submitted to a single energy source and the retrieved gas and/or solid phase(s) is/are analyzed by different techniques.     

Electromagnetic waves observed by Venus Express at periapsis: Detection and analysis techniques

The magnetometer on Venus Express was designed to be able to obtain 128 Hz samples of the magnetic field from two sensors in a gradiometer configuration. This mode is used around periapsis to determine whether the signals reported at low altitudes near 100 Hz, had the properties of electromagnetic waves generated by electric discharges in the Venus atmosphere. The lack of a magnetic cleanliness program and the shortness of the magnetometer boom make this a challenging measurement. Fortunately the signals are sufficiently strong that they can be easily resolved with rather straightforward analysis techniques.     

Astrophysical implications of higher-dimensional gravity

We review the implications of modern higher-dimensional theories of gravity for astrophysics and cosmology. In particular, we discuss the latest developments of STM theory in connection with dark matter, particle dynamics and the cosmological constant, as well as related aspects of quantum theory. There are also more immediate tests of extra dimensions, notably involving perturbations of the cosmic 3K microwave background and the precession of a supercooled gyroscope in Earth orbit. We also outline some general features of embeddings, and include pictures of the big bang as viewed from a higher dimension.