Search for extraterrestrial life using chiral molecules: mandelate racemase as a test case

We have investigated an enzymatic racemization reaction as a marker for extraterrestrial life, which resulted in a change in optical rotation of a mandelic acid over time, as measured by polarimetry. Mandelate racemase was active in aqueous buffer in a temperature range between 0 degrees C and 70 degrees C and also in concentrated ammonium salt solutions and water-in-oil microemulsions in a temperature range between -30 degrees C and 60-70 degrees C; however, the enzyme was not active in several organic cryosolvents. Thus, we have demonstrated that concentrated ammonium salt solutions and water-in-oil microemulsions, both of which are able to form on extraterrestrial planets and moons in the presence of liquid water, are suitable media for enzyme reactions at subzero temperatures. Kinetic data for the mandelate racemase reaction obtained by polarimetry, while reproducible and internally consistent, differed significantly from several sets of data obtained previously by other methods such as chromatography and hydrogen-deuterium exchange. However, we conclude that reactions yielding a polarimetric signal, such as the racemizations employed in this work, are suitable mechanisms by which to utilize a change in chirality over time as a tool to detect signs of life.     

Infrared spectra and radiation stability of H2O2 ices relevant to Europa

In this paper we present spectra of H2O2-containing ices in the near- and mid-infrared (IR) regions. Spectral changes on warming are shown, as is a comparison of near-IR bands of H2O and H2O2-containing ices. An estimate of the A-value (absolute intensity) for the largest near- IR feature of H2O2 is given. Radiation-decay half-lives are reported for 19 K and 80 K, and are related to the surface radiation doses on Europa. The radiation data show that H2O2 destruction is slower at 80 K than 19 K, and are consistent with the claim that icy material in the outermost micrometer of Europa's surface has been heavily processed by radiation.     

Space motion sickness

Space motion sickness, presumably triggered by sudden entry into a weightless environment, occurred with unexpected frequency and severity among astronauts who flew the Skylab missions. Recovery from symptoms was complete within 3-5 days, and as revealed by the Skylab M131 Human Vestibular Function Experiment, all crewmembers were immune to experimentally induced motion sickness after mission day 8. This syndrome has been recognized as a possible threat to the early mission well-being and operational efficiency of at least some individuals who will fly space missions in the future. The causes of space motion sickness are not clearly understood, nor have satisfactory methods been identified to date for its prediction, prevention and treatment. In order to minimize the potential impact of this syndrome on Space Shuttle crew operations the National Aeronautics and Space Administration has organized a broad program of inter-disciplinary research involving a large number of scientists in the United States. Current research on the etiology of space motion sickness is based to a large extent on the so called sensory conflict theory. Investigations of the behavioral and neurophysiological consequences of intralabyrinthine, as well as intermodality sensory conflict are being performed. The work in this area is being influenced by the presumed alterations that occur in otolith behavior in weightlessness. In addition to sensory conflict, the possible relationship between observed cephalad shifts of body fluids in weightlessness and space motion sickness is being investigated. Research to date has failed to support the fluid shift theory. Research underway to identify reliable test methods for the prediction of susceptibility to space motion sickness on an individual basis includes attempts to (a) correlate susceptibility in different provocative environments; (b) correlate susceptibility with vestibular and non-vestibular response parameters, the latter including behavioral, hemodynamic and biochemical factors and (c) correlate susceptibility with rate of acquisition and length of retention of sensory adaptation. Controlled studies are also being performed during parabolic flight as a means of attempting to validate predictive tests for susceptibility to this syndrome. Research to develop new or improved countermeasures for space motion sickness is underway in two primary areas. One of these involves anti-motion sickness drugs. Significant achievements have been realized with regard to the identification of new highly efficacious drug combinations, dose levels and routes of administration. Although pronounced individual variations must be accounted for in selecting the optimum drug and dose level, combinations of promethazine plus ephedrine or scopolamine plus dexidrine are presently the drugs of choice. Work is also underway to identify side effects associated with anti-motion sickness drug use and to identify new drugs which may selectively modify activity in central neural pathways involved in motion sickness. In addition to research on drugs, efforts are being made to develop practical vestibular training methods. Variables which influence rate of acquisition of adaptation, length of retention of adaptation and transfer of protective adaptation to new environments are being evaluated. Also, included in this area is the use of biofeedback and autogenic therapy to train individuals to regulate autonomic responses associated with motion sickness. While valuable new knowledge is expected to evolve from these combined research programs, it is concluded that the final validation of predictive tests and countermeasures will require a series of controlled space flight experiments.     

ATS-6 Parabolic Antenna for Mounting Solar Cells

Calculations are made to obtain the raw electrical power that can be generated by using an ATS-6 type deployable parabolic dish as a surface for mounting solar cells without seriously interfering with its normal function as an antenna. A minimum of a few hundred watts to a maximum of a few kilowatts are generated during the apparent course of the Sun around the spacecraft. Academically, it seems that deployable solar cell panels along with their booms can be avoided.     

MESSENGER and the Chemistry of Mercury’s Surface

The instrument suite on the MErcury Surface, Space ENvironment, GEochemistry, and Ranging (MESSENGER) spacecraft is well suited to address several of Mercury’s outstanding geochemical problems. A combination of data from the Gamma-Ray and Neutron Spectrometer (GRNS) and X-Ray Spectrometer (XRS) instruments will yield the surface abundances of both volatile (K) and refractory (Al, Ca, and Th) elements, which will test the three competing hypotheses for the origin of Mercury’s high bulk metal fraction: aerodynamic drag in the early solar nebula, preferential vaporization of silicates, or giant impact. These same elements, with the addition of Mg, Si, and Fe, will put significant constraints on geochemical processes that have formed the crust and produced any later volcanism. The Neutron Spectrometer sensor on the GRNS instrument will yield estimates of the amount of H in surface materials and may ascertain if the permanently shadowed polar craters have a significant excess of H due to water ice. A comparison of the FeO content of olivine and pyroxene determined by the Mercury Atmospheric and Surface Composition Spectrometer (MASCS) instrument with the total Fe determined through both GRNS and XRS will permit an estimate of the amount of Fe present in other forms, including metal and sulfides.     

L'avion,plateforme d'observations scientifiques

Transition between high altitude manned observatories and unmanned balloon-borne or rocket-borne experiments is achieved with high flying aircrafts, at altitudes above tropopause (>12 km), which became readily available, at reasonable cost and reliability, in the past five or ten years.This paper reviews the development of scientific uses of aircrafts, especially for astronomy and geophysics, with some emphasis placed on infrared problems, closely related to the scale height of the chief infrared absorber, i.e. telluric water vapor.Absorbers distribution vs altitude and spectral characteristics are summarized (Figures 1, 2, 3).Capabilities of various available aircrafts are compared (Table I) and the various ways to consider modifications are discussed: structural modifications or design problems to fit telescopes or light collectors on board. Tables II and III list the advantages of airborne observations, compared to other spatial carriers, and also the specific problems connected with aircrafts. Adopted solutions to these problems are exposed (Figures 4, 5, 6, 7) and costs are briefly discussed.Finally, a few examples of scientific results, gathered in the few past years from aircraft, are given, both in astronomy and in geophysics.     

Rendezvous Navigation and Guidance Using a Hand-Held Self-Powered Digital Computer

This paper describes a simplified solution of the space rendezvous problem based on optical sightings taken with a hand-held sextant entered into and processed by a small digital computer. Compared to the manual method described in [1], this approach greatly reduces the astronaut's work load. Also, the computer can provide a more accurate solution, can present more flight plan options (allowing more tradeoffs between fuel usage and time), and can allow greater freedom in the sequencing of measurements and maneuvers. Physical characteristics, input-output parameters, and logic design of the computer are briefly described.     

Numerical simulation of a boiling up fluid flow in the variable cross-section channels

A physical and mathematical model of a boiling-up fluid flow in the variable crosssection channels is proposed. The numerical model is based on the solution of the Navier-Stokes nonstationary equations for compressible fluid by the implicit finite-difference method. We present the results of the numerical modeling for two-phase flow characteristics at the initial stage of the evaporation process and the steady-state quasistationary flow of a two-phase medium.