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Yingtai Chen Yumin Li Hong Zhang Yi Xie Xuezhong Chen Jinyu Ren Xiaowei Zhang Zijiang Zhu Hongliang Liu Yawei Zhang 《Advances in Space Research (includes Cospar's Information Bulletin, Space Research Today)》2010
The aim of this study was to estimate the acute effects of low dose 12C6+ ions or X-ray radiation on human immune function. The human peripheral blood lymphocytes (HPBL) of seven healthy donors were exposed to 0.05 Gy 12C6+ ions or X-ray radiation and cell responses were measured at 24 h after exposure. The cytotoxic activities of HPBL were determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT); the percentages of T and NK cells subsets were detected by flow cytometry; mRNA expression of interleukin (IL)-2, tumor necrosis factor (TNF)-α and interferon (IFN)-γ were examined by real time quantitative RT-PCR (qRT-PCR); and these cytokines protein levels in supernatant of cultured cells were assayed by enzyme-linked immunosorbent assays (ELISA). The results showed that the cytotoxic activity of HPBL, mRNA expression of IL-2, IFN-γ and TNF-α in HPBL and their protein levels in supernatant were significantly increased at 24 h after exposure to 0.05 Gy 12C6+ ions radiation and the effects were stronger than observed for X-ray exposure. However, there was no significant change in the percentage of T and NK cells subsets of HPBL. These results suggested that 0.05 Gy high linear energy transfer (LET) 12C6+ radiation was a more effective approach to host immune enhancement than that of low LET X-ray. We conclude that cytokines production might be used as sensitive indicators of acute response to LDI. 相似文献
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Conceptual design of a bioregenerative life support system containing crops and silkworms 总被引:1,自引:0,他引:1
Enzhu Hu Sergey I. Bartsev Hong Liu 《Advances in Space Research (includes Cospar's Information Bulletin, Space Research Today)》2010
This article summarizes a conceptual design of a bioregenerative life support system for permanent lunar base or planetary exploration. The system consists of seven compartments – higher plants cultivation, animal rearing, human habitation, water recovery, waste treatment, atmosphere management, and storages. Fifteen kinds of crops, such as wheat, rice, soybean, lettuce, and mulberry, were selected as main life support contributors to provide the crew with air, water, and vegetable food. Silkworms fed by crop leaves were designated to produce partial animal nutrition for the crew. Various physical-chemical and biological methods were combined to reclaim wastewater and solid waste. Condensate collected from atmosphere was recycled into potable water through granular activated carbon adsorption, iodine sterilization, and trace element supplementation. All grey water was also purified though multifiltration and ultraviolet sterilization. Plant residue, human excrement, silkworm feces, etc. were decomposed into inorganic substances which were finally absorbed by higher plants. Some meat, ingredients, as well as nitrogen fertilizer were prestored and resupplied periodically. Meanwhile, the same amount and chemical composition of organic waste was dumped to maintain the steady state of the system. A nutritional balanced diet was developed by means of the linear programming method. It could provide 2721 kcal of energy, 375.5 g of carbohydrate, 99.47 g of protein, and 91.19 g of fat per capita per day. Silkworm powder covered 12.54% of total animal protein intakes. The balance of material flows between compartments was described by the system of stoichiometric equations. Basic life support requirements for crews including oxygen, food, potable and hygiene water summed up to 29.68 kg per capita per day. The coefficient of system material closure reached 99.40%. 相似文献
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针对火箭设计过程中的气动特性计算,对计算流体力学软件FASTRAN进行二次开发。在C++语言环境下编写火箭气动设计平台中FASTRAN自动化批处理模块。用户使用此模块输入作业的关键参数,自动批量生成脚本文件,并从后台加载计算进程,使用脚本功能自动控制参数设置和计算过程,完成后导出气动力与气动载荷数据,以内置格式自动生成结果报告。这一过程代替人工操作,减少了工作量,提高了设计效率。以两种火箭构型为例,计算并分析得出不同状态下的升、阻力系数和压心位置随马赫数的变化规律。计算结果与实验数据吻合良好,误差在可接受范围内,可以为火箭的初步设计提供参考和依据。 相似文献
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随着我国航空航天技术的飞速发展,气动计算软件集成技术日趋成熟,但用户在并行计算中需要手动输入的操作较多。鉴于此,通过编程开发了基于TCP/IP协议的FTP客户端应用程序,实现了对网格文件的信息采集、过滤并将其和参数、脚本文件等批量自动上传的功能。根据批处理文件中的命令,调用Windows平台自带的客户端Telnet,向远程集群管理节点发出命令,远程启动服务器集群的并行计算任务。最后,在客户端实现了远程控制服务器集群上的计算流体力学软件Fluent进行并行计算。结果表明:使用该远程控制系统能够减少用户输入操作,提高计算效率,保证数据的实时更新。 相似文献
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针对线性相对运动假设下的碰撞概率计算问题,提出了等效矩形域方法。利用该方法将概率积分计算进行近似处理,推导出概率密度积分的解析表达式。针对空间目标误差椭球形状固定的情况,给出了最大碰撞概率的计算方法。对目标在交会时刻相距较远和接近碰撞的情况进行了碰撞概率以及最大碰撞概率计算。通过将计算结果与空间压缩无穷级数法的对比,验证了等效矩形域方法近似计算碰撞概率积分的可靠性,同时对于不同的碰撞概率计算情况,等效矩形域方法显示出更高精确度和更好的估计偏差稳定性。 相似文献