Cardiovascular and hormonal responses to bicycle exercise during lower body negative pressure

The purpose was to combine bicycle exercise and LBNP as a model to investigate the mechanisms regulating circulation during gravitatiobal stresses. METHODS: Cardiac Output (CO) by acetylene-, argon-, oxygen rebreathing; Heart Rate (HR) from ECG; Mean Arterial Pressure (MAP) by arm cuff; Plasma Nor-Epinephrine (NE), Epinephrine (E), and Lactate (HLa) by isotope and enzymatic techniques respectively. Total Peripheral Resistance (TPR)=MAP/CO and stroke volume (SV)=CO/HR. Six subjects exercised at 180–200 Watts in the upright position on a mechanically braked computer controlled small bicycle ergometer placed in a LBNP box. The above parameters were measured at rest and at 5 and 9 min of exercise without and with LBNP at −30 or −40 mmHg (depending on LBNP tolerance). RESULTS AND CONCLUSIONS: In the face of an increased sympathetic nervous activity (Ne+E, TPR, and HR increased) during exercise in LBNP, there was a decrease in CO and SV indicating that the venous return was insufficient. However, HLa was unchanged demonstrating that the blood flow to the working muscles did not suffer.     

The microlesion concept in HZE particle dosimetry.

High energy, high-Z (HZE) particles are present in high-altitude and high-inclination satellite orbits. Most of the HZE dose above LET = 200 keV/micrometer is due to Fe nuclei. Individual HZE particles can damage several cells adjacent to one another along the particle track in tissue. The outcome has been described as a "microlesion" by D. Grahn. The present study attempts to define conditions for microlesions in specific tissues, to seek biological evidence that microlesions are produced, and to evaluate the microlesion as a potentially useful unit of dose in assessing hazards to spaceworkers. Microlesions in individuals cells and hair follicles have been described. Microbial studies have provided some evidence for independent secondary electron action. Whether or not a few hundred microlesions would be damaging to the whole organism depends upon the nature of damage to critical tissues. For example, cancer may occur if microlesions kill several cells in a straight line and mutate other cells alongside the particle track. Fe particle irradiation of the mouse Harderian gland (Fry et al., this issue) produces tumors efficiently. Microlesions in the lens, cornea, and retina need to be considered. Further dialogue is required before a final decision can be made concerning the most appropriate way to assess the HZE hazard.     

Antideuterons as an indirect dark matter signature: Si(Li) detector development and a GAPS balloon mission

The General AntiParticle Spectrometer (GAPS) is a novel approach for indirect dark matter searches that exploits cosmic antideuterons. GAPS complements existing and planned direct dark matter searches as well as other indirect techniques, probing a different and unique region of parameter space in a variety of proposed dark matter models. The GAPS method involves capturing antiparticles into a target material with the subsequent formation of an excited exotic atom. The exotic atom decays with the emission of atomic X-rays and pions from the nuclear annihilation, which uniquely identifies the captured antiparticle. This technique has been verified through the accelerator testing at KEK in 2004 and 2005. The prototype flight is scheduled from Hokkaido, Japan in 2011, preparatory for a long duration balloon flight from the Antarctic in 2014.     

DORIS geodesy: A dynamic determination of geocentre location

Geoscience Australia contributed a multi-satellite, multi-year weekly time series to the International DORIS Service combined submission for the construction of International Terrestrial Reference Frame 2008 (ITRF2008). This contributing solution was extended to a study of the capability of DORIS to dynamically estimate the variation in the geocentre location. Two solutions, comprising different constraint configurations of the tracking network, were undertaken. The respective DORIS satellite orbit solutions (SPOT-2, SPOT-4, SPOT-5 and Envisat) were verified and validated by comparison with those produced at the Goddard Space Flight Center (GSFC), DORIS Analysis Centre, for computational consistency and standards. In addition, in the case of Envisat, the trajectories from the GA determined SLR and DORIS orbits were compared. The results for weekly dynamic geocentre estimates from the two constraint configurations were benchmarked against the geometric geocentre estimates from the IDS-2 combined solution. This established that DORIS is capable of determining the dynamic geocentre variation by estimating the degree one spherical harmonic coefficients of the Earth’s gravity potential. It was established that constrained configurations produced similar results for the geocentre location and consequently similar annual amplitudes. For the minimally constrained configuration Greenbelt–Kitab, the mean of the uncertainties of the geocentre location were 2.3, 2.3 and 7.6 mm and RMS of the mean uncertainties were 1.9, 1.2 and 3.5 mm for the X, Y and Z components, respectively. For GA_IDS-2_Datum constrained configuration, the mean of the uncertainties of the geocentre location were 1.7, 1.7 and 6.2 mm and RMS of the mean uncertainties were 0.9, 0.7 and 2.9 mm for the X, Y and Z components, respectively. The mean of the differences of the two DORIS dynamic geocentre solutions with respect to the IDS-2 combination were 1.6, 4.0 and 5.1 mm with an RMS of the mean 21.2, 14.0 and 31.5 mm for the Greenbelt–Kitab configuration and 4.1, 3.9 and 4.3 mm with an RMS 8.1, 9.0 and 28.6 mm for the GA_IDS-2_Datum constraint configuration. The annual amplitudes for each component were estimated to be 5.3, 10.8 and 11.0 mm for the Greenbelt–Kitab configuration and 5.3, 9.3 and 9.4 mm for the GA_IDS-2_Datum constraint configuration. The two DORIS determined dynamic geocentre solutions were compared to the SLR determined dynamic solution (which was determined from the same process of the GA contribution to the ITRF2008 ILRS combination) gave mean differences of 3.3, −4.7 and 2.5 mm with an RMS of 20.7, 17.5 and 28.0 mm for the X, Y and Z components, respectively for the Greenbelt–Kitab configuration and 1.1, −5.4 and 4.4 mm with an RMS of 9.7, 13.3 and 24.9 mm for the GA_IDS-2_Datum configuration. The larger variability is reflected in the respective amplitudes. As a comparison, the annual amplitudes of the SLR determined dynamic geocentre are 0.9, 1.0 and 6.8 mm in the X, Y and Z components. The results from this study indicate that there is potential to achieve precise dynamically determined geocentre from DORIS.     

Wide field cameras for SAX

SAX is an Italian X-ray satellite with a Dutch contribution that will be placed in orbit in 1994. The prime scientific object of SAX is to cover an energy bandwidth that ranges from 0.1 keV up to 200 keV. Among other instruments, SAX will consist of two X-ray Wide Field Cameras built by the Space Research Organisation Netherlands at Utrecht. The WFCs are based on the coded mask principle, the reconstruction of the image takes place on ground. The field of view is 20 degrees square full width at half maximum (FWHM), the angular resolution 5 arcminutes (FWHM) and the energy band ranges from 1.8 to 30 keV with a resolution of 18% at 6 keV. The sensitive area is 200 cm² at 6 keV. The mask pattern is based on a pseudo random array with 255 × 257 elements of 1 mm², 50% of which are transparent.     

The INFRARED SPACE OBSERVATORY (ISO)

The INFRARED SPACE OBSERVATORY (ISO), a project of the European Space Agency (ESA), will make various astronomical observations in the wavelength range of 2 to 200 μm. Two-thirds of its observing time will be available to guest observers via the traditional route of proposal submission. ISO will be launched in 1995 by an Ariane 4 from Kourou (Guyana) and be brought into a very elongated orbit with a 24hr period of which 16 hr can be used for astronomical observations. The payload module is essentially a large cryostat with a tank that will be filled with over 2000 litres of superfluid helium to keep the instruments cold (2 to 4 K) during an expected lifetime of 18 months. Inside the dewar, there is a Ritchey-Chretien telescope with a primary mirror of diameter 60cm. Four instruments, each provided by a different PI consortium, share the ISO focal plane. These instruments are : a photometer, a camera and two spectrometers — one for the wavelength range 2–45 μm and the other for 45–180 μm.     

SIGMA observations of two new hard X-ray and soft gamma-ray transients: GX 354-0 and Nova Persei

We report the first detection of two soft gamma ray transients GX 354-0 and Nova Persei (GRO J0422+32) by the coded-mask telescope SIGMA. Only preliminary results are presented with regard to Nova Persei while special emphasis is given to the data on GX 354-0 which has been monitored during the 1992 February–April survey of the Galactic Center. GX 354-0 underwent two flares of about two week duration and its average spectrum is well described by a thermal Bremsstrahlung model or a broken power law whereas the Nova Persei spectrum seems to be similar to the one observed for GRS 1124-684 in Musca.     

Optical, X-ray and γ-ray observations of compact objects in globular clusters

In the past three years, a new era of study of globular clusters has begun with multiwavelength observations from the current generation of astronomical telescopes in space. We review the recent results obtained from our studies of compact binaries and x-ray sources in globulars with ROSAT and HST as well as our balloon-borne hard x-ray telescope EXITE and ground-based observations (CTIO). With ROSAT, we have obtained the most sensitive high resolution soft x-ray images of clusters which show multiple low luminosity sources in cluster cores that are likely indicative of the long-sought population of cataclysmic variables (CVs). We have obtained deep H images of two clusters with HST and found CV candidates for 3 of the ROSAT sources in the core of NGC 6397. New CTIO imaging and spectroscopy of two ‘dim source’ fields in ω-Cen are also described. With EXITE we carried out the first hard x-ray imaging observations of the cluster 47 Tuc; such studies can ultimately limit the populations of millisecond pulsars and pulsar emission mechanisms. A long ROSAT exposure on 47 Tuc also shows probable cluster diffuse emission, possibly due to hot gas from ablating millisecond pulsars. Multiwavelength studies of globular clusters may provide new constraints on problems as diverse as the origin of CVs and LMXBs and the origin of hot gas in globulars.     

A design procedure for the phase-controlled parallel-loadedresonant inverter

High-frequency-link power conversion and distribution based on a resonant inverter has been recently proposed. The design of several topologies is reviewed and a simple approximate design procedure is developed for the phase-controlled parallel-loaded resonant inverter. This design procedure seeks to ensure the expected benefits of resonant conversion and is verified by data from a laboratory 2.5 kVA, 20-kHz converter. A simple phasor analysis is introduced as a useful approximation for design purposes. Experimental results show that under transient conditions such as load short-circuit, a reversal of the expected commutation sequence is possible. This should be accounted for in the design of the power circuit, or prevented by the design of the controller     

An exact expression for resolution cell area in special case ofbistatic radar systems

An exact expression for the bistatic resolution-cell area (A _B) is developed for the special case in which either the transmit or receive antenna has a broad azimuth beamwidth or is omnidirectional. Quantitative examples are presented to illustrate the variation of A_B with location. A comparison is made with the performance of a commonly used approximation formula