Estimation of risk based on multiple events in radiation carcinogenesis of rat skin.

In the multistage theory of carcinogenesis, cells progress to cancer through a series of discrete, irreversible, heritable genetic alterations or mutations. However data on radiation-induced cancer incidence in rat skin suggests that some part of an intermediate repairable alteration may occur. Data are presented on cancer induction in rat skin exposed to the following radiations: 1. an electron beam (LET=0.34 keV/um, 2. a neon ion beam (LET=25 keV/um and 3. an argon ion beam (LET=125 keV/um. The latter 2 beams were generated by the Bevalac at the Lawrence Berkeley Laboratory, Berkeley, CA. About 6.0 cm2 of skin was irradiated per rat. The rats were observed every 6 weeks for at least 78 weeks and tumors were scored at first occurrence. Several histological types of cancer, including squamous and basal cell carcinomas, were induced. The cancer yield versus radiation dose was fitted by the quadratic equation (Y(D)=CLD+BD2), and the parameters C and B were estimated for each type of radiation. Analysis of the DNA from the electron-induced carcinomas indicated that K-ras and/or c-myc oncogenes were activated in all tumors tested, although only a small proportion of neon-induced tumors showed similar activation. In situ hybridization indicated that the cancers contain subpopulations of cells with differing amounts of c-myc and H-ras amplification. The results are consistent with the idea that ionizing radiation produces carcinogenically relevant lesions via 2 repairable events at low LET and via a non-repairable, linked event pathway at high LET; either pathway may advance the cell by 1 stage in the multistage model. The model, if validated, permits the direct calculation of cancer risk in rat skin in a way that can be subjected to experimental testing.     

Measurement of middle atmospheric ozone density profile by rocket-borne radiometer onboard KSR-II

KSR-II, a two-stage sounding rocket of KARI was launched successfully at the Korean Peninsula on June 11, 1998. The apogee of the rocket was 137 km. For the ozone measurement, 8-channel UV and visible radiometers were onboard the rocket. The rocket measured an in situ stratospheric and mesospheric ozone density profile over Korea during its ascending phase using the radiometer and transmitted the data to ground station in real time. The maximum ozone density occurs near 25 km. Retrieved profile has a random error (1σ) of approximately 15% for altitude below 20km, 7% between 20-50 km and 10% greater than 50 km. The retrieved data were compared with Dobson spectrophotometer, ozonesonde, and HALOE onboard the UARS. Our results are in reasonable agreements with others.     

Excel在数值计算中的应用

本文介绍了用Excel电子表格解决数值计算中的计算问题，并用图表形式表示出运算结果。     

“自准”赝像及识别

置平面镜于凸透镜后,则凸透镜前焦平面上的物成像于该物平面上,即“自准”成像.满足其它条件也能成像于物平面.分析不同条件下像的形成及其特点,并给出识别自准成像的判据.     

某型客车噪声源的测试与研究

本文通过对某型客车的噪声测试分析，识别出该型客车的主要噪声源，为进一步采取有效的降噪措施提供了必要依据。     

基于容差分配的直升机多约束运动系统的应用与研究

本文以某民用直升机动力舱多约束运动系统的容差分配设计为例,阐述和分析了多约束运动系统容差基准的选取、分配以及设计补偿等。可以为多约束运动系统设计提供方法和参考。     

基于EAB资源的交织编译码器的设计与实现

提出了一种新的基于EAB资源交织编译码设计方案，利用FPGA技术实现了数字通信中交织器和解交织器，构建了具体的算法模型，并说明了设计中实际产生的问题及解决方法。     

上海天文台火星卫星定轨软件系统

具有自主知识产权的上海天文台火星卫星定轨软件MarsODP已经初步完成编写工作,该软件以应用于我国未来的火星探测计划为目标。本文介绍了火星定轨软件MarsODP的研制背景,对软件需求进行了分析,介绍了软件的结构设计,利用模拟数据对软件进行了测试,并给出了一些实测数据的处理结果。     

高锁螺栓、高锁螺母的国产化研制

高锁螺栓、高锁螺母具有高强度、高抗疲劳、预紧力安装、自锁等优良特性,它们在直升机结构中广泛应用。本文论述了高锁螺栓、高锁螺母的国产化研制特点及关键技术。研制结果表明,国产化UNJ螺纹的钛合金高锁螺栓、不锈钢抗拉型高锁螺母尺寸与国外标准件一致,可实现互换安装,产品性能达到了国外同类件性能指标要求,可以替代安装。