Monte Carlo track structure studies of energy deposition and calculation of initial DSB and RBE.

Estimation of exposure due to environmental and other sources of radiations of high-LET and low-LET is of interest in radiobiology and radiation protection for risk assessment. To account for the differences in effectiveness of different types of radiations various parameters have been used. However, the relative inadequacy of the commonly used parameters, including dose, fluence, linear energy transfer, lineal energy, specific energy and quality factor, has been made manifest by the biological importance of the microscopic track structure and primary modes of interaction. Monte Carlo track structure simulations have been used to calculate the frequency of energy deposition by radiations of high- and low-LET in target sizes similar to DNA and higher order genomic structure. Tracks of monoenergetic heavy ions and electrons were constructed by following the molecular interaction-by-interaction histories of the particles down to 10 eV. Subsequently, geometrical models of these assumed biological targets were randomly exposed to the radiation tracks and the frequency of energy depositions obtained were normalized to unit dose in unit density liquid water (l0(3) kg m-3). From these data and a more sophisticated model of the DNA, absolute yields of both single- and double-strand breaks expressed in number of breaks per dalton per Gray were obtained and compared with the measured yields. The relative biological effectiveness (RBE) for energy depositions in cylindrical targets has been calculated using 100 keV electrons as the reference radiation assuming the electron track-ends contribution is similar to that in 250 kV X-ray or Co60 gamma-ray irradiations.     

Electronically steerable plasma mirror based radar-concept andcharacteristics

An alternative to using a phased array to steer a radar beam is to electronically control the orientation of an inertialess broadband microwave reflector. Recent experiments have demonstrated that a planar plasma mirror immersed in a magnetic field can be formed with electron densities high enough to reflect X-band microwave beams. A plasma mirror performs like a metal mirror, but it is inertialess. Compared to high performance phased array systems, a plasma mirror based radar system is much simpler and is therefore more affordable. Electronic steering of microwave beams using a plasma mirror permits the use of wide instantaneous bandwidth waveforms. Potential areas of application for a plasma mirror based antenna system include ship self-defense, high-resolution radar imaging, target identification, electronic countermeasures, high data rate communications, spread spectrum links and remote sensing. As a reflector, the plasma mirror exhibits extremely low loss and the reflectivity is very nearly 100%. Since a perfectly reflecting object cannot radiate, the noise temperature contribution of the plasma mirror to the antenna temperature is likely to be small. The plasma sheet can be steered in elevation by tilting the magnetic field, and steering in azimuth may be accomplished by designating cathode initiation sites. Switching times between successive mirror orientations may be less than 20 μs     

Spaceflight and clinorotation cause cytoskeleton and mitochondria changes and increases in apoptosis in cultured cells.

The cytoskeleton is a complex network of fibers that is sensitive to environmental factors including microgravity and altered gravitational forces. Cellular functions such as transport of cell organelles depend on cytoskeletal integrity; regulation of cytoskeletal activity plays a role in cell maintenance, cell division, and apoptosis. Here we report cytoskeletal and mitochondria alterations in cultured human lymphocyte (Jurkat) cells after exposure to spaceflight and in insect cells of Drosophila melanogaster (Schneider S-1) after exposure to conditions created by clinostat rotation. Jurkat cells were flown on the space shuttle in Biorack cassettes while Schneider S-1 cells were exposed to altered gravity forces as produced by clinostat rotation. The effects of both treatments were similar in the different cell types. Fifty percent of cells displayed effects on the microtubule network in both cell lines. Under these experimental conditions mitochondria clustering and morphological alterations of mitochondrial cristae was observed to various degrees after 4 and 48 hours of culture. Jurkat cells underwent cell divisions during exposure to spaceflight but a large number of apoptotic cells was also observed. Similar results were obtained in Schneider S-1 cells cultured under clinostat rotation. Both cell lines displayed mitochondria abnormalities and mitochondria clustering toward one side of the cells which is interpreted to be the result of microtubule disruption and failure of mitochondria transport along microtubules. The number of mitochondria was increased in cells exposed to altered gravity while cristae morphology was severely affected indicating altered mitochondria function. These results show that spaceflight as well as altered gravity produced by clinostat rotation affects microtubule and mitochondria organization and results in increases in apoptosis. Grant numbers: NAG 10-0224, NAG2-985.     

Fuel cell status, 1994

The high efficiency environmental benefits and other attributes of fuel cells have attracted world-wide attention to the technology. Approximately 250 phosphoric acid fuel cell (PAFC) power units, 35 molten carbonate fuel cell (MCFC) stacks, and 12 solid oxide fuel cell (SOFC) modules have been or are being operated. Total capacity installed or operating is close to 45 MW. Fuel cell development has progressed to where complete power plants have reached nearly 16,000 operating hours and this continues to increase. Developers in the U.S. and Japan have embarked on extensive government and private programs to commercialize the technology in those countries and abroad. By mid-1994, the U.S. sold and shipped to other countries at least 33 PAFC 200 kW plants, 20 675 kW PAFC stacks, two SOFC 25 kW modules, and one MCFC system. Additional units have been produced for the domestic market. There is intense interest in Japan where there are very stringent environmental regulations and fuel prices are high. The fuel cell can respond with its combined attributes of low emissions and relative high efficiency. In Europe, the environmental cleanliness of fuel cell power units holds the promise of preserving the quality of life, motivating support and development of the technology. Canada and Australia have spawned important development programs. Interest continues to increase in other parts of the world. The author reviews the 1994 status and outlines the future development trends in this area     

Effects of Reduced SAR Azimuth Processing

Several approaches are evaluated for reducing the large data handling and processing loads associated with synthetic aperture radar (SAR) imaging systems. The effects of data abbreviation on SAR images were studied theoretically as well as experimentally with SEASAT-A data. Image degradation was measured in terms of azimuth resolution and signal-to-clutter ratio. It was found that the degradation of image quality to data rate reduction is graceful. With high time-bandwidth product signals, little or no azimuth resolution degradation was noticed with several data bandwidth reduction techniques that achieve data reduction factors of up to 8. The signal-to-clutter ratio was found to decrease slowly with increasing reduction in data rate.     

On small active region filaments,fibrils and surges

High resolution Hα images and magnetograms (0.2 arc s) of an active region were obtained in alternating time series at 42 s cadences using the Swedish 1-m Solar Telescope on 2004 August 21. The Hα filtergrams reveal an active region filament and surges consisting of thread-like structures which have widths similar to the widths of chromospheric fibrils, both recorded down to the resolution limit in the best images. All observed structures in the active region appear highly dynamic. Fibrils show counterstreaming strongly resembling the counterstreaming threads in filaments.     

Satellite observations of sea ice

An overview is presented of Antarctic and Arctic sea ice studies using data from the Nimbus-5 ESMR and the Nimbus-7 SMMR passive microwave radiometers. Four years (1973–1976) of ESMR data for the Antarctic Ocean define the characteristics of the seasonal cycle including regional contrasts and interannual variations. Major advances include the discovery of the Weddell polynya and the presence of substantial areas of open water in the Antarctic winter pack ice. Regional differences in sea ice extent on time-scales of about a month are shown to be associated with variations in surface-wind fields. In the Arctic, the computation of sea ice concentration is complicated by the presence of multiyear ice, but the amount of multiyear ice becomes an important measurable quantity with dual-polarized, multifrequency passive microwave sensors. Analysis of SMMR data demonstrates its advantage for studying the spatial and temporal variability of the Arctic ice cover. Large observed interannual variations in the distribution of the multiyear pack ice and the presence of significant divergent areas in the central Arctic during winter contrast markedly with the classical view of the Arctic pack ice.     

Calibration techniques for magnetometers implementing on-board de-spinning algorithms

The Fluxgate Magnetometer experiments on-board the European Space Agency’s four spacecraft Cluster Mission have the capability to store sampled magnetic field vectors in the instrument memory, either as a full resolution ‘event capture’ or as spin-resolution vectors transformed into a non-spinning co-ordinate system (de-spun). The latter capability has ensured a dataset is available which extends the partial orbital coverage achieved during nominal operations in the first years of operation. The on-board de-spin is achieved using a Walsh function with Haar coefficients and allows for up to 27 h additional data per non-coverage interval. A number of commissioning orbits were used to verify the accuracy of data collected by the de-spin mode, whereby individual spacecraft were operated separately in a number of standard normal sampling and de-spin mode combinations. Up to the present time, this data has not been available to the Cluster community. We present results here comparing the performance of the on-board de-spin algorithm versus the normal sampling modes over a number of boundary layer crossings, describe the techniques used for calibration and timeline recovery, and outline the context in which the data may be usable in future studies.     

Results from the ESA SREM monitors and comparison with existing radiation belt models

The Standard Radiation Environment Monitor (SREM) is a simple particle detector developed for wide application on ESA satellites. It measures high-energy protons and electrons of the space environment with a 20° angular resolution and limited spectral information. Of the ten SREMs that have been manufactured, four have so far flown. The first model on STRV-1c functioned well until an early spacecraft failure. The other three are on-board, the ESA spacecraft INTEGRAL, ROSETTA and PROBA-1. Another model is flying on GIOVE-B, launched in April 2008 with three L-2 science missions to follow: both Herschel and Planck in 2008, and GAIA in 2011). The diverse orbits of these spacecraft and the common calibration of the monitors provides a unique dataset covering a wide range of B-L* space, providing a direct comparison of the radiation levels in the belts at different locations, and the effects of geomagnetic shielding. Data from the PROBA/SREM and INTEGRAL/IREM are compared with existing radiation belt models.     

Light microscopic analysis of the gravireceptor in Xenopus larvae developed in hypogravity.

The paper describes an investigation of the influence of gravity on the early differentiation of gravity receptors in Xenopus embryos and larvae. There is evidence that the expression of crystals in the saccus endolymphaticus was statistically greater when the embryos developed in near weightlessness (hypogravity) than on earth. The function of these crystals is unknown but they may contribute to the functioning of the vestibular apparatus.