Chronic hyperhydration and hematological changes in trained subjects during prolonged restriction of motor activity

The objective of this investigation was to evaluate the effect of a daily intake of fluid and salt supplementation (FSS) on the hemoglobin content of endurance trained athletes during hypokinesia (decreased number of steps from 10,000 to 3000 steps per day). The studies were performed on 30 long-distance runners who had a VO2max average of 66 ml kg-1 min-1 and were in the age range of 19-24 years. Prior to their exposure to hypokinesia (HK) of 364 days, all volunteers were on an average of 10,000 steps per day. All volunteers were divided into three equal groups: the first group underwent normal ambulatory life (control subjects), the second group was kept under continuous restriction of motor activity (hypokinetic subjects), and the third group was placed under continuous restriction of motor activity and consumed 26 ml water kg-1 body weight daily and 0.1 g sodium chloride kg-1 body weight in the form of supplementation (hyperhydrated subjects). For simulation of the hypokinetic effect, the number of steps taken per day by the second and third groups of volunteers was restricted to an average of 3000. During the hypokinetic period we determined reticulocytes (Rt), hemoglobin (Hb), hematocrit (Hct), plasma volume (PV), red blood cell (RBC) mass and VO2max. In hyperhydrated volunteers the content of Hb and Hct decreased significantly, while PV, RBC mass and Rt count increased significantly. In hypokinetic volunteers Hb and Hct increased, while PV, RBC and Rt decreased significantly. It was concluded that chronic hyperhydration may be used to attentuate an increase in the Hb content of physically conditioned subjects during prolonged restriction of motor activity.     

Solar wind charge states measured by ULYSSES/SWICS in the south polar hole

The Ulysses mission now has an extensive data base covering several passes of the south polar coronal hole as the spacecraft proceeds to higher latitudes. Using composition measurements from the SWICS experiment on the Ulysses spacecraft, we have obtained charge state distributions, and hence inferred coronal ionization temperatures, for several solar wind species. In particular, we present an overview of Oxygen ionization temperature measurements, based on the O⁷⁺/O⁶⁺ ratio, for the period January 1993 until April 1994 (23°S to 61°S heliographic latitude), and detailed Oxygen, Silicon and Iron charge state distributions of the south polar hole during a two month period of nearly continuous hole coverage, Dec 1993–Jan 1994 (45°S to 52°S heliographic latitude).     

Study of distribution functions of interplanetary particles accelerated at co-rotating interaction region at∼5A.U.

We report the results of a study of the 12-hour average distribution functions of high Z nuclei as measured over a 10-day interval on the Ulysses spacecraft at a helioradius of5.2 A.U. We use the good time and atomic mass resolution of the composition aperture of the HI-SCALE instrument to determine the form of the distribution functions for C, O, Ne, Mg, Si, and Fe over the energy range 0.5–16 MeV/nucl. We find that the distribution functions of these ions can be organized by characteristic velocities that have values ranging between2000–3500 km/sec over this interval.     

Astrobiology from exobiology: Viking and the current Mars probes

The development of an Astrobiology Program is an extension of current exobiology programs. Astrobiology is the scientific study of the origin, distribution, evolution, and future of life in the universe. It encompasses exobiology; formation of elements, stars, planets, and organic molecules; initiation of replicating organisms; biological evolution; gravitational biology; and human exploration. Current interest in life on Mars provides the scientific community with an example of scientific inquiry that has mass appeal. Technology is mature enough to search for life in the universe.     

A systems and concurrent engineering framework for the integrated development of space products

This paper proposes a framework for the integrated development of space products. The framework is called ‘total view framework’ because it provides the total set of product, process and organisation elements and their interactions from the outset in the development process. It uses systems engineering (SE) and concurrent engineering (CE) in an integrated manner, as part of the same framework. The framework extends the application of the SE process to life cycle processes and their performing organisations and applies CE at all levels of the hierarchical product breakdown structure. The ‘total view framework’ is supported by a method, called ‘concurrent structured analysis method’, that consists of the three analysis processes: requirements, functional and physical. These processes mirror the bulk of the SE process and are applied concurrently to product, process and organisations. The outputs of the method are requirements, functional attributes, physical attributes and the interactions among them. These outputs are then analysed using a clustering algorithm and a complexity metric based on cohesion and coupling shows the clustering effects.     

Study of water-salt metabolism and renal function in cosmonauts

In manned space flights the renal function and water-salt metabolism undergo substantial changes. With the reserve capabilities of kidneys in mind, their function and regulation of the water-salt balance were investigated in cosmonauts postflight and in Earth-bound simulation experiments with the aid of water loading, hormonal injections (pituitrin, engiotensin, DOCA, ACTH); water- and ion-release were also studied during LBNP and physical exercises. The cosmonauts who performed space flights of 2 to 5 days showed water retention and increased urine excretion of salts during the first postflight days in response to a water load. After the 18-day flight water excretion remained unchanged whereas salt excretion increased. The capacity for osmotic concentration and urine dilution did not alter. The study of the hormonal effect in simulation experiments of different duration demonstrated a normal renal response to the hormonal excretion. After the LBNP tests and physical exercises the water- and salt-excretion declined; a correlation between the level of water- and salt-excretion and the level of these loads was established. The data on the blood- and urine-ionic composition, excretion of nitrogen metabolites, and hormones postflight as well as the results of load and functional tests suggest that changes in the renal function of cosmonauts in weightlessness are associated with regulatory effects on the kidney rather than disturbances in the function of nephron cells.     

Summary of medical investigations in the U.S.S.R. manned space missions.

The results of biomedical investigations carried out in the U.S.S.R. manned space missions are discussed. Their basic result is well-documented evidence that man can perform space flights of long duration. The investigations have demonstrated no direct correlation between inflight or postflight physiological reactions of crewmembers and flight duration. In all likelihood, this can be attributed to the fact that special exercises done inflight efficiently prevented adverse effects of weightlessness. However, human reactions to weightlessness need further study. They include negative calcium balance and anemia as well as vestibulo-autonomic disorders shown by crewmembers at early stages of weightlessness. Attention should be given to psychological, social-psychological and ethical problems that may also limit further increase in flight duration.     

Motion of a Planet with a Complex Structure

The motion of a planet consisting of a mantle and a core (solid bodies) connected by a viscoelastic layer and interacting with each other and an external point mass by the law of gravitation is considered. The mutual motions of the core and mantle are investigated assuming that the centers of mass of the planet and external point mass moves along undisturbed Keplerian orbits around the common center of mass of the system. The planetary core and mantle have an axial symmetry and different principal moments of inertia, which leads to a displacement of the center of mantle relative to the center of core and to their mutual rotations. The results obtained on the basis of averaged equations are illustrated by the example of the Earth–Moon system.     

Some technical aspects of gaseous detonation

This paper briefly describes two attempts to utilize detonative combustion processes to MHD conversion of thermal energy of fuel to electrical energy and bonding of atmospheric nitrogen. For this purpose a continuous impulse detonation chamber with a frequency up to 200 cps was constructed. Using methane-oxygen-nitrogen mixtures the chamber was maintained in stable operation for several hundred hours. Oil was also employed as fuel.Estimates based on experimental data showed that up to 2% of chemical energy of the fuel may be converted into electrical energy. The use of an accelerating nozzle may improve this result.The concentration of nitrogen oxide in combustion products of the detonation wave was higher by 14% than that expected under usual combustion conditions.The advantages of this type of apparatus are: absence of compressors for fuel and oxidant, impulse current generation, low temperatures of chamber walls, and operation over a large range of operating conditions.Problems associated with the effect of the magnetic field on the propagation of the detonation wave are discussed and the possibility of applying the Zeldovich theory to the case of MHD interaction is described. It is shown that the detonation velocity may either increase or decrease depending on the relative orientation of the direction of magnetic field with respect to the detonation wave.