Reduced lymphocyte activation in space: role of cell-substratum interactions.

We investigated the effect of substratum adhesiveness on stimulated lymphocyte blastogenesis by reducing and blocking cell adhesion with poly (2-hydroxyethyl methacrylate) (poly-HEMA) in a simple on-ground system. Cells grown on medium-thick and thick poly-HEMA films were rounded in shape and displayed no signs of spreading. By contrast, on tissue culture plastic and very thin poly-HEMA films, they showed clear signs of spreading. The mitogenic response of lymphocytes grown on thick poly-HEMA films was reduced by up to 68% of the control (tissue culture plastic). Interferon-gamma production was near zero when the cells were grown on the least adhesive substratum. On uncoated plastic, activated lymphocytes subjected to high gravity (20g) exhibited an increased proliferation rate (40%) compared with 1g. By contrast, on poly-HEMA, high gravity did not improve lymphocyte responsiveness. These results show that activated lymphocytes need to anchor and spread prior to achieving an optimal proliferation response. We conclude that decreased lymphocyte adhesion could contribute to the depressed in vitro lymphocyte responsiveness found in the microgravity conditions of space flight.     

Several recent findings concerning the dynamics of the Earth's magnetotail

Several recent results concerning the nature of the Earth's magnetotail are briefly reviewed. These observational findings include: (1) the three-dimensional character of the plasma sheet via a comprehensive survey of proton bulk flows, (2) a region of earthward flowing plasmas at the interfaces of the plasma sheet and magnetotail lobes during magnetic substorm recovery, and (3) the signature of electrostatic acceleration for protons within the jetting plasmas from magnetotail fireballs.Proceedings of the Symposium on Solar Terrestrial Physics held in Innsbruck, May–June 1978.     

Ionospheric total electron content response to annular solar eclipse on June 21, 2020

The effects of physical events on the ionosphere structure is an important field of study, especially for navigation and radio communication. The paper presents the spatio-temporal ionospheric TEC response to the recent annular solar eclipse on June 21, 2020, which spans across two continents, Africa and Asia, and 14 countries. This eclipse took place on the same day as the June Solstice. The Global Navigation Satellite System (GNSS) based TEC data of the Global Ionosphere Maps (GIMs), 9 International GNSS Service (IGS) stations and FORMOSAT-7/COSMIC-2 (F7/C2) were utilized to analyze TEC response during the eclipse. The phases of the TEC time series were determined by taking the difference of the observed TEC values on eclipse day from the previous 5-day median TEC values. The results showed clear depletions in the TEC time series on June 21. These decreases were between 1 and 9 TECU (15–60%) depending on the location of IGS stations. The depletions are relatively higher at the stations close to the path of annular eclipse than those farther away. Furthermore, a reduction of about ?10 TECU in the form of an equatorial plasma bubble (EPB) was observed in GIMs at ~20° away from the equator towards northpole, between 08:00–11:00 UT where its maximum phase is located in southeast Japan. Additionally, an overall depletion of ~10% was observed in F7/C2 derived TEC at an altitude of 240 km (hmF2) in all regions affected by the solar eclipse, whereas, significant TEC fluctuations between the altitudes of 100 km ? 140 km were analyzed using the Savitzky-Golay smoothing filter. To prove TEC depletions are not caused by space weather, the variation of the sunspot number (SSN), solar wind (V_SW), disturbance storm-time (Dst), and Kp indices were investigated from 16th to 22nd June. The quiet space weather before and during the solar eclipse proved that the observed depletions in the TEC time series and profiles were caused by the annular solar eclipse.     

Order out of Randomness: Self-Organization Processes in Astrophysics

Self-organization is a property of dissipative nonlinear processes that are governed by a global driving force and a local positive feedback mechanism, which creates regular geometric and/or temporal patterns, and decreases the entropy locally, in contrast to random processes. Here we investigate for the first time a comprehensive number of (17) self-organization processes that operate in planetary physics, solar physics, stellar physics, galactic physics, and cosmology. Self-organizing systems create spontaneous “order out of randomness”, during the evolution from an initially disordered system to an ordered quasi-stationary system, mostly by quasi-periodic limit-cycle dynamics, but also by harmonic (mechanical or gyromagnetic) resonances. The global driving force can be due to gravity, electromagnetic forces, mechanical forces (e.g., rotation or differential rotation), thermal pressure, or acceleration of nonthermal particles, while the positive feedback mechanism is often an instability, such as the magneto-rotational (Balbus-Hawley) instability, the convective (Rayleigh-Bénard) instability, turbulence, vortex attraction, magnetic reconnection, plasma condensation, or a loss-cone instability. Physical models of astrophysical self-organization processes require hydrodynamic, magneto-hydrodynamic (MHD), plasma, or N-body simulations. Analytical formulations of self-organizing systems generally involve coupled differential equations with limit-cycle solutions of the Lotka-Volterra or Hopf-bifurcation type.     

Abundance and diversity of microbial inhabitants in European spacecraft-associated clean rooms

The determination of the microbial load of a spacecraft en route to interesting extraterrestrial environments is mandatory and currently based on the culturable, heat-shock-surviving portion of microbial contaminants. Our study compared these classical bioburden measurements as required by NASA's and ESA's guidelines for the microbial examination of flight hardware, with molecular analysis methods (16S rRNA gene cloning and quantitative PCR) to further develop our understanding of the diversity and abundance of the microbial communities of spacecraft-associated clean rooms. Three samplings of the Herschel Space Observatory and its surrounding clean rooms were performed in two different European facilities. Molecular analyses detected a broad diversity of microbes typically found in the human microbiome with three bacterial genera (Staphylococcus, Propionibacterium, and Brevundimonas) common to all three locations. Bioburden measurements revealed a low, but heterogeneous, abundance of spore-forming and other heat-resistant microorganisms. Total cell numbers estimated by quantitative real-time PCR were typically 3 orders of magnitude greater than those determined by viable counts, which indicates a tendency for traditional methods to underestimate the extent of clean room bioburden. Furthermore, the molecular methods allowed the detection of a much broader diversity than traditional culture-based methods.     

Effect of Semi-solid Isothermal Heat Treatment on Microstructure of VW63Z Alloy

The effects of isothermal heat treatment on the semi-solid microstructure evolution of VW63Z (Mg-6Gd-3Y-0.4Zr, wt.%) alloy are studied. It shows that the microstructure of VW63Z alloy could transform from equiaxed crystal to semi-solid spherical crystal after isothermal heat treatment above 620 ºC. With the heating temperature elevating from 620 ºC to 635 ºC and the holding time prolonging from 10 min to 35 min, the liquid fraction increases gradually. The semi-solid microstructure evolution of VW63Z alloy can be divided into three stages, i.e., particle coarsening and spheroidization;particle necking, coalescence, and Ostwald ripening;and dynamic equilibrium. The semi-solid process window of VW63Z alloy ranges from 620 ºC to 635 ºC, where the best process parameters are holding at 635 ºC for 20 min?30 min. The solid fraction, the average particle size, and the shape factor are 41.1%?53.8%, 81.5 μm?83.2 μm, and 0.70?0.75, respectively. The maximum relative deviations of the solid fraction, the particle size, and the shape factor at different heights of the same billet are 44.6%, 17.4%, and 16.6%, respectively, which means that it should pay attention to the uniformity of edge and core of VW63Z alloy during isothermal heat treatment. The driving force of microstructure is supposed to be the reduction of solid-liquid interface free energy.     

尾座式无人飞行器鲁棒容错编队控制

针对尾座式无人飞行器编队在执行器故障、严重的非线性和耦合性、参数不确定性、外界扰动等影响下的容错控制问题进行了研究。提出了一种鲁棒容错编队控制方法来实现一群尾座式无人飞行器在执行器故障情况下的期望编队飞行。所构建的控制器由2部分组成：标称控制器和干扰补偿控制器。设计标称控制器使系统实现期望的控制性能,利用干扰补偿控制器抑制多种不确定性和执行器故障的影响。通过理论分析证明了系统的鲁棒稳定性,并通过数值仿真验证了算法的有效性。     

Experimental investigation of hot and cold side jet interaction with a supersonic cross-flow

This paper reports on experimental aerodynamic investigations on a high-speed missile with side jet control especially with regard to the interaction of cold and hot side jets with supersonic cross-flow. The hot jets were generated with solid propellants. To analyze the effect of the hot jet in relation to side jet control, wall pressure distributions were measured in the area of jet interaction. As a test parameter, the jet pressure ratio was varied and schlieren images were taken to visualize the shocks. In addition, the development of large-scale vortex structures on hot gas jets was detected with high-speed videos. The frame sequences show periodical turbulent jet structures and permit the manual evaluation of their spatial distribution. Analyzing the images, the convection velocities of the large-scale structures and their convection angles were determined. The convection velocities reach the magnitude of cross-flow velocity shortly behind the hot jet exit.     

Millimeter wave radiation sources visible in solar corona

Coronal millimeter wave sources (CMMS) have been observed at radio frequencies 22–90 GHz (at wavelengths 3–13 mm). The observed CMMS have been classified into three different categories according to their time scale and relation to other wave-length events. The CMMS indicate enhancement of electron density in the corona, as well as magnetic loop structures. The CMMS are evidence of dynamical processes taking place at the lower levels of the corona, propagating into the higher levels.     

Net electric power of concentrating solar mirror systems for application in space as a function of the distance to the sun

The use of solar radiation by means of concentrating solar mirror systems, such as parabolic and spheric configurations, mainly is an engineering problem. A decisive characteristic for the optimisation of a complete system with turboelectric power conversion is the thermal cycle applied. Besides the Carnot process, here taken up into the study as an ideal comparative process, suitable processes for the technological realisation are the Brayton process and the Rankine process. The Brayton process is a typical gas turbine process using only the gaseous phase. The Rankine process is a steam engine process using liquid and gaseous phase.The work in hand shows how such solar systems with turboelectric conversion are optimised with respect to their specific weight (kg/kW_e) and how the distance to the sun as well as technological data enter into the analysis.As expected, the Carnot cycle as an ideal comparative process for both types of systems shows the best results for the optimum specific mass of the system. Regarding the real processes, the Rankine cycle shows more favourable characteristics than the Brayton cycle. The difference of the specific masses of the real processes mainly results from the different thermal conditions at the radiator.The influence of the distance to the sun is as expected. The nearer to the sun the solar power system operates, the better is the optimum specific mass of the system. For distances to the sun between 0.3 and 1.0 AU the spheric system shows a better behaviour than the parabolic system. For distances to the sun greater than 2.0 AU the parabolic system shows better behaviour of the specific weight. In the region between 1 and 2 AU the better optimum specific mass of the system belongs to the technological data used in the analysis.