Individual differences in susceptibility to motion sickness among six Skylab astronauts

One of the Skylab experiments dealt with motion sickness, comparing susceptibility in the workshop aloft with susceptibility preflight and postflight. Tests were conducted on and after mission-day 8 (MD 8) by which time the astronauts were adapted to working conditions. Stressful accelerations were generated by requiring the astronauts, with eyes covered, to execute standardized head movements (front, back, left, and right) while in a chair that could be rotated at angular velocities up to 30 rpm. The selected endpoint was either 150 discrete head movements or a very mild level of motion sickness. In all rotation experiments aloft, the five astronauts tested (astronaut 1 did not participate) were virtually symptom free, thus demonstrating lower susceptibility aloft than in preflight and postflight tests on the ground when symptoms were always elicited. Inasmuch as the eyes were covered and the canalicular stimuli were the same aloft as on the ground, it would appear that lifting the stimulus to the otolith organs due to gravity was an important factor in reducing susceptibility to motion sickness even though the transient stimuli generated under the test conditions were substantial and abnormal in pattern. Some of the astronauts experienced motion sickness under operational conditions aloft or after splashdown, but attention is centered chiefly on symptoms manifested in zero gravity. None of the Skylab-II crew (astronauts 1 to 3) was motion sick aloft. Astronaut 6 of the Skylab-III crew (astronauts 4 to 6) experienced motion sickness within an hour after transition into orbit; this constitutes the earliest such diagnosis on record under orbital flight conditions. The eliciting stimuli were associated with head and body movements, and astronaut 6 obtained relief by avoiding such movements and by one dose of the drug combination 1-scopolamine 0.35 mg + d-amphetamine 5.0 mg. All three astronauts of Skylab-III experienced motion sickness in the workshop where astronaut 6 was most susceptible and astronaut 4, least susceptible. The higher susceptibility of SL-III crewmen in the workshop, as compared with SL-II crewmen, may be attributable to the fact that they were based in the command module less than one-third as long as SL-II crewmen. The unnatural movements, often resembling acrobatics, permitted in the open spaces of the workshop revealed the great potentialities in weightlessness for generating complex interactions of abnormal or unusual vestibular and visual stimuli. Symptoms were controlled by body restraint and by drugs, but high susceptibility to motion sickness persisted for 3 days and probably much longer; restoration was complete on MD 7. From the foregoing statements it is clear that on and after MD 8 the susceptibility of SL-II and SL-III crewmen to motion sickness under experimental conditions was indistinguishable. The role played by the acquisition of adaptation effects prior to MD 8 is less clear and is a subject to be discussed.     

Changes in chromatin and nucleic acids in rat tissues after two-week spaceflight

The quantitative changes in nucleic acids and chromatin breakdown were followed in blood, thymus and spleen in rats after 14 day flights on board the biosatellites Cosmos-1887 and Cosmos-2044. Quantitative nucleic acid changes within 8-11 h after landing were only mild, most statistically non-significant. An analysis at 48 h after landing showed a marked decrease in a total content of DNA and RNA in spleen and thymus. Within 8-11 h after landing, the symptoms of chromatin breakdown were found as is seen in an increased concentration of its fragments-polydeoxyribonucleotides. The obtained results show that a partial adaptation to microgravity occurs up to flight day 14 in lymphoid organs. Adaptation is accompanied with a reappearing of the sensitive cells. Their chromatin breaks down, then, in a final phase of flight due to hypergravity stress manifesting itself by a temporary increase in polydeoxyribonucleotide concentration several hours after landing. The results are discussed in relation to the changes in chosen parameters after shorter or more prolonged flights.     

Automorphogenesis and gravitropism of plant seedlings grown under microgravity conditions.

Plant seedlings exhibit automorphogenesis on clinostats. The occurrence of automorphogenesis was confirmed under microgravity in Space Shuttle STS-95 flight. Rice coleoptiles showed an inclination toward the caryopsis in the basal region and a spontaneous curvature in the same adaxial direction in the elongating region both on a three-dimensional (3-D) clinostat and in space. Both rice roots and Arabidopsis hypocotyls also showed a similar morphology in space and on the 3-D clinostat. In rice coleoptiles, the mechanisms inducing such an automorphic curvature were studied. The faster-expanding convex side of rice coleoptiles showed a higher extensibility of the cell wall than the opposite side. Also, in the convex side, the cell wall thickness was smaller, the turnover of the matrix polysaccharides was more active, and the microtubules oriented more transversely than the concave side, and these differences appear to be causes of the curvature. When rice coleoptiles grown on the 3-D clinostat were placed horizontally, the gravitropic curvature was delayed as compared with control coleoptiles. In clinostatted coleoptiles, the corresponding suppression of the amyloplast development was also observed. Similar results were obtained in Arabidopsis hypocotyls. Thus, the induction of automorphogenesis and a concomitant decrease in graviresponsiveness occurred in plant shoots grown under microgravity conditions.     

Metabolic changes in rats subjected to space flight for 18.5 days in the biosatellite Cosmos 936

From an investigation of the activity of six glucocorticoid dependent liver enzymes, the existence of chronic, transient, stress-induced hypercorticosteronaemia during flight is probable. This hypercorticosteronaemia arises from weightlessness and induces gluconeogenesis. Weightlessness also caused substantial increases in liver glycogen level. The increased lipolytic activity and that of lipoprotein lipase in several groups of animals could be interpreted as enhancement of fat mobilization and utilization under the influence of stress. As this latter enhancement was also found in ground-based controls, it may have been due to the stress of handling rather than to space flight per se.     

A Correlation Polarimeter for Noise-Like Signals

Optimum estimation (tracking) of the polarization plane of a linearly polarized electromagnetic wave is determined when the signal is a narrow-band Gaussian random process with a polarization plane angle which is also a Gaussian random process. This model is Compared to previous work and is applicable to space communication. The estimator performs a correlation operation similar to an amplitude -comparison monopulse angle tracker, giving the name correlation polarimeter. Under large signal-to-noise ratio (SNR), the estimator is causal. Performance of the causal correlation polarimeter is evaluated for arbitrary SNR. Optimum precorrelation filtering is determined. With low SNR, the performance of this system is far better than that of previously developed systems. Practical implementation is discussed. A scheme is given to reduce the effect of linearly polarized noise.     

Receiver operating characteristics for the coherent UWB randomnoise radar

An ultrawideband (UWB) random-noise radar operating in the 1-2 GHz frequency band has been developed and held-tested at a 200 m range at the University of Nebraska. A unique heterodyne correlation technique based on a delayed transmitted waveform using a photonic delay line has been used to inject coherence within this system. The performance of this radar, assuming a point target, has been investigated from a statistical point of view by developing the theoretical basis for the system's receiver operating characteristics (ROC). Explicit analytical expressions for the joint probability density function (pdf) of the in-phase (I) and quadrature (Q) components of the receiver output have been derived under the assumption that the input signals are partially correlated Gaussian processes. The pdf and the complementary cumulative distribution function (cdf) for the envelope of the receiver output are also derived. These expressions are used to relate the probability of detection (P_d) to the probability of false alarm (P_f ) for different numbers of integrated samples, and the results are analyzed     

Hydra — A 3-dimensional electron and ion hot plasma instrument for the POLAR spacecraft of the GGS mission

HYDRA is an experimental hot plasma investigation for the POLAR spacecraft of the GGS program. A consortium of institutions has designed a suite of particle analyzers that sample the velocity space of electron and ions between 2 keV/q – 35 keV/q in three dimensions, with a routine time resolution of 0.5 s. Routine coverage of velocity space will be accomplished with an angular homogeneity assumption of 16°, appropriate for subsonic plasmas, but with special 1.5° resolution for electrons with energies between 100 eV and 10 keV along and opposed to the local magnetic field. This instrument produces 4.9 kilobits s^–1 to the telemetry, consumes on average 14 W and requires 18.7 kg for deployment including its internal shielding. The scientific objectives for the polar magnetosphere fall into four broad categories: (1) those to define the ambient kinetic regimes of ions and electrons; (2) those to elucidate the magnetohydrodynamic responses in these regimes; (3) those to assess the particle populations with high time resolution; and (4) those to determine the global topology of the magnetic field. In thefirst group are issues of identifying the origins of particles at high magnetic latitudes, their energization, the altitude dependence of the forces, including parallel electric fields they have traversed. In thesecond group are the physics of the fluid flows, regimes of current, and plasma depletion zones during quiescent and disturbed magnetic conditions. In thethird group is the exploration of the processes that accompany the rapid time variations known to occur in the auroral zone, cusp and entry layers as they affect the flow of mass, momentum and energy in the auroral region. In thefourth class of objectives are studies in conjunction with the SWE measurements of the Strahl in the solar wind that exploit the small gyroradius of thermal electrons to detect those magnetic field lines that penetrate the auroral region that are directly open to interplanetary space where, for example, the Polar Rain is observed.     

On Optimal Control of Linear Systems in the Presence of Multiplicative Noise

This correspondence considers the problem of optimal regulator design for discrete time linear systems subjected to white state-dependent and control-dependent noise in addition to additive white noise in the input and the observations. A pseudo-deterministic problem is first defined in which multiplicative and additive input disturbances are present, but noise-free measurements of the complete state vector are available. This problem is solved via discrete dynamic programing. Next is formulated the problem in which the number of measurements is less than that of the state variables and the measurements are contaminated with state-dependent noise. The inseparability of control and estimation is brought into focus, and an "enforced separation" solution is obtained via heuristic reasoning in which the control gains are shown to be the same as those in the pseudo-deterministic problem. An optimal linear state estimator is given in order to implement the controller.