Experiences in Managing the Prometheus Project

Congress authorized NASA's Prometheus Project in February 2003, with the first Prometheus mission slated to explore the icy moons of Jupiter. The project had two major objectives: 1) to develop a nuclear reactor that would provide unprecedented levels of power and show that it could be processed safely and operated reliably in space for long-duration, deep-space exploration; and 2) to explore the three icy moons of Jupiter - Callisto, Ganymede, and Europa - and return science data that would meet the scientific goals as set forth in the Decadal Survey Report of the National Academy of Sciences. Early in project planning, it was determined that the development of the Prometheus nuclear-powered spaceship would be complex and require the intellectual knowledge residing at numerous organizations across the country. In addition, because of the complex nature of the project and the multiple partners, approaches beyond those successfully used to manage a typical JPL project would be needed. This describes the key experiences in managing Prometheus, which should prove useful for future projects of similar scope and magnitude.     

Review of primary spaceflight-induced and secondary reloading-induced changes in slow antigravity muscles of rats.

We have examined the light and electron microscopic properties of hindlimb muscles of rats flown in space for 1-2 weeks on Cosmos biosatellite flights 1887 and 2044 and Space Shuttle missions Spacelab-3, Spacelab Life Sciences-1 and Spacelab Life Sciences-2. Tissues were obtained both inflight and postflight permitting definition of primary microgravity-induced changes and secondary reentry and gravity reloading-induced alterations. Spaceflight causes atrophy and expression of fast fiber characteristics in slow antigravity muscles. The stresses of reentry and reloading reveal that atrophic muscles show increased susceptibility to interstitial edema and ischemic-anoxic necrosis as well as muscle fiber tearing with disruption of contractile proteins. These results demonstrate that the effects of spaceflight on skeletal muscle are multifaceted, and major changes occur both inflight and following return to Earth's gravity.     

A neutral gas mass spectrometer to measure the chemical composition of the stratosphere

The Polar Balloon Atmospheric Composition Experiment (P-BACE) is a new generation of neutral gas mass spectrometer based on the time-of-flight principle. P-BACE is the scientific experiment on the Mars Environment Analog Platform (MEAP) flown successfully on a balloon mission in summer 2008. The MEAP mission was flown with a 334,000 m³ helium balloon in the stratosphere on a semicircular trajectory from northern Sweden around the North Pole to Canada using the summer northern hemispheric wind current. The atmospheric conditions at an atmospheric altitude of 35–40 km are remarkably similar to those on the surface of Mars and thus the balloon mission was an ideal testbed for our mass spectrometer P-BACE. Originally this instrument was designed for in situ measurements of the chemical composition of the Martian atmosphere.P-BACE has a unique mass range from 0 to 1000 amu/q with a mass resolution m/Δm (FWHM) > 1000, and the dynamic range is at least six orders of magnitude. During this experiment, the acquisition of one mass spectrum is a sum of 65,535 single spectra, recorded in a time frame of 66 s.The balloon mission lasted 5 days and had successfully demonstrated the functionality of the P-BACE instrument during flight conditions. We had recorded more than 4500 mass spectra. With little modifications, P-BACE can be used on a planetary mission for Mars, but for example also for Venus or Mercury, if placed on a satellite.     

Advanced regenerative environmental control and life support systems: Air and water regeneration

Extended manned space missions will require regenerative life support techniques. Past U.S. manned missions used nonregenerative expendables, except for a molecular sieve-based carbon dioxide removal system aboard Skylab. The resupply penalties associated with expendables becomes prohibitive as crew size and mission duration increase. The U.S. Space Station, scheduled to be operational in the 1990's, is based on a crew of four to sixteen and a resupply period of 90 days or greater. It will be the first major spacecraft to employ regenerable techniques for life support. The paper uses the requirements for the Space Station to address these techniques.     

Analysis of total visual and CCD V-broadband observations of Comet C/1995 O1 (Hale-Bopp): 1995–2001

We developed a general method for determination of water production rates from groundbased visual observations and applied it to Comet Hale–Bopp. Our main objective is to extend the method to include total visual magnitude observations obtained with CCD detector and V filter in the analysis of total visual magnitudes. We compare the CCD V-broadband careful observations of Liller [Liller, W. Pre-perihelion CCD photometry of Comet 1995 O1 (Hale-Bopp). Planet. Space Sci. 45, 1505–1513, 1997; Liller, W. CCD photometry of Comet C/1995 O1 (Hale-Bopp): 1995–2000. Int. Comet Quart. 23(3), 93–97, 2001] with the total visual magnitude observations from experienced international observers found in the International Comet Quarterly (ICQ) archive. A data set of ∼400 CCD observations covering about the same 6 years time span of the ∼12,000 ICQ selected total visual magnitude observations were used in the analysis. A least-square method applied to the water production rates, yields power laws as a function of the heliocentric distances for the pre- and post-perihelion phases. The average dimension of the nucleus as well as its effective active area is determined and compared with values published in the literature.     

Comparison of mesopause region meteor radar winds,medium frequency radar winds and low frequency drifts over Germany

During 2004 and 2005 measurements of mesospheric/lower thermospheric (80–100 km) winds have been carried out in Germany using three different ground-based systems, namely a meteor radar (36.2 MHz) at the Collm Observatory (51.3°N, 13°E), a MF radar (3.18 MHz) at Juliusruh (54.6°N, 13.4°E) and the LF D1 measurements using a transmitter (177 kHz) at Zehlendorf near Berlin and receivers at Collm with the reflection point at 52.1°N, 13.2°E. This provides the possibility of comparing the results of different radar systems in nearly the same measuring volume. Meteor radar winds are generally stronger than the winds observed by MF and especially by LF radars. This difference is small near 80 km but increases with height. The difference between meteor radar and medium frequency radar winds is larger during winter than during summer, which might indicate an indirect influence of gravity waves on spaced antenna measurements.     

Gamma ray astrophysics and signatures of axion-like particles

We propose that axion-like particles (ALPs) with a two-photon vertex, consistent with all astrophysical and laboratory bounds, may lead to effects in the spectra of high-energy gamma-ray sources detectable by satellite or ground-based telescopes. We discuss two kinds of signatures: (i) a peculiar spectral depletion due to gamma rays being converted into ALPs in the magnetic fields of efficient astrophysical accelerators according to the “Hillas criterion”, such as jets of active galactic nuclei or hot spots of radio galaxies; (ii) an appearance of otherwise invisible sources in the GeV or TeV sky due to back-conversion of an ALP flux (associated with gamma-ray emitters suffering some attenuation) in the magnetic field of the Milky Way. These two mechanisms might also provide an exotic way to avoid the exponential cutoff of very high energy gamma-rays expected due to the pair production onto the extragalactic background light.     

On the levels of enzymatic substrate specificity: implications for the early evolution of metabolic pathways.

The most frequently invoked explanation for the origin of metabolic pathways is the retrograde evolution hypothesis. In contrast, according to the so-called "patchwork" theory, metabolism evolved by the recruitment of relatively inefficient small enzymes of broad specificity that could react with a wide range of chemically related substrates. In this paper it is argued that both sequence comparisons and experimental results on enzyme substrate specificity support the patchwork assembly theory. The available evidence supports previous suggestions that gene duplication events followed by a gradual neoDarwinian accumulation of mutations and other minute genetic changes lead to the narrowing and modification of enzyme function in at least some primordial metabolic pathways.