Review of primary spaceflight-induced and secondary reloading-induced changes in slow antigravity muscles of rats.

We have examined the light and electron microscopic properties of hindlimb muscles of rats flown in space for 1-2 weeks on Cosmos biosatellite flights 1887 and 2044 and Space Shuttle missions Spacelab-3, Spacelab Life Sciences-1 and Spacelab Life Sciences-2. Tissues were obtained both inflight and postflight permitting definition of primary microgravity-induced changes and secondary reentry and gravity reloading-induced alterations. Spaceflight causes atrophy and expression of fast fiber characteristics in slow antigravity muscles. The stresses of reentry and reloading reveal that atrophic muscles show increased susceptibility to interstitial edema and ischemic-anoxic necrosis as well as muscle fiber tearing with disruption of contractile proteins. These results demonstrate that the effects of spaceflight on skeletal muscle are multifaceted, and major changes occur both inflight and following return to Earth's gravity.     

A technique for estimating the probability of radiation-stimulated failures of integrated microcircuits in low-intensity radiation fields: Application to the Spektr-R spacecraft

In developing radio-electronic devices (RED) of spacecraft operating in the fields of ionizing radiation in space, one of the most important problems is the correct estimation of their radiation tolerance. The “weakest link” in the element base of onboard microelectronic devices under radiation effect is the integrated microcircuits (IMC), especially of large scale (LSI) and very large scale (VLSI) degree of integration. The main characteristic of IMC, which is taken into account when making decisions on using some particular type of IMC in the onboard RED, is the probability of non-failure operation (NFO) at the end of the spacecraft’s lifetime. It should be noted that, until now, the NFO has been calculated only from the reliability characteristics, disregarding the radiation effect. This paper presents the so-called “reliability” approach to determination of radiation tolerance of IMC, which allows one to estimate the probability of non-failure operation of various types of IMC with due account of radiation-stimulated dose failures. The described technique is applied to RED onboard the Spektr-R spacecraft to be launched in 2007.     

A three-dimensional plasma and energetic particle investigation for the wind spacecraft

This instrument is designed to make measurements of the full three-dimensional distribution of suprathermal electrons and ions from solar wind plasma to low energy cosmic rays, with high sensitivity, wide dynamic range, good energy and angular resolution, and high time resolution. The primary scientific goals are to explore the suprathermal particle population between the solar wind and low energy cosmic rays, to study particle accleration and transport and wave-particle interactions, and to monitor particle input to and output from the Earth's magnetosphere.Three arrays, each consisting of a pair of double-ended semi-conductor telescopes each with two or three closely sandwiched passivated ion implanted silicon detectors, measure electrons and ions above 20 keV. One side of each telescope is covered with a thin foil which absorbs ions below 400 keV, while on the other side the incoming <400 keV electrons are swept away by a magnet so electrons and ions are cleanly separated. Higher energy electrons (up to 1 MeV) and ions (up to 11 MeV) are identified by the two double-ended telescopes which have a third detector. The telescopes provide energy resolution of E/E0.3 and angular resolution of 22.5°×36°, and full 4 steradian coverage in one spin (3 s).Top-hat symmetrical spherical section electrostatic analyzers with microchannel plate detectors are used to measure ions and electrons from 3 eV to 30 keV. All these analyzers have either 180° or 360° fields of view in a plane, E/E0.2, and angular resolution varying from 5.6° (near the ecliptic) to 22.5°. Full 4 steradian coverage can be obtained in one-half or one spin. A large and a small geometric factor analyzer measure ions over the wide flux range from quiet-time suprathermal levels to intense solar wind fluxes. Similarly two analyzers are used to cover the wide range of electron fluxes. Moments of the electron and ion distributions are computed on board.In addition, a Fast Particle Correlator combines electron data from the high sensitivity electron analyzer with plasma wave data from the WAVE experiment (Bougeretet al., in this volume) to study wave-particle interactions on fast time scales. The large geometric factor electron analyzer has electrostatic deflectors to steer the field of view and follow the magnetic field to enhance the correlation measurements.     

Ionospheric wave processes during HF heating experiments

Effects of ionospheric modification produced by powerful high frequency radio waves are studied using the method of field-aligned scattering of diagnostic HF radio signals. Observations of scattered HF signals have been made by the Doppler spectrum method. Analysis of the experimental data shows the appearance of quasiperiodic variations in Doppler frequency shift f_d, with periods 30–60 s during the heating cycles. Powerful HF waves are assumed to excite the Alfvén resonator generating oscillations of the magnetic field lines in the heated region and giving rise to f_d artificial variations and magnetic pulsations. In the case of continuous action of the powerful HF transmitter ionospheric waves are sometimes observed with periods 12–25 min, typical of medium-scale travelling ionospheric disturbances.     

Exobiological exploration of Mars.

Of all the other planets in the solar system, Mars remains the most promising for further elucidating concepts about chemical evolution and the origin of life. Strategies were developed to pursue three exobiological objectives for Mars exploration: determining the abundance and distribution of the biogenic elements and organic compounds, detecting evidence of an ancient biota on Mars, and determining whether indigenous organisms exist anywhere on the planet. The three strategies are quite similar and, in fact, share the same sequence of phases. In the first phase, each requires global reconnaissance and remote sensing by orbiters to select sites of interest for detailed in situ analyses. In the second phase, lander missions are conducted to characterize the chemical and physical properties of the selected sites. The third phase involves conducting "critical" experiments at sites whose properties make them particularly attractive for exobiology. These critical experiments would include, for example, identification of organics, detection of fossils, and detection of extant life. The fourth phase is the detailed analysis of samples returned from these sites in Earth-based laboratories to confirm and extend previous discoveries. Finally, in the fifth phase, human exploration is needed to establish the geological settings for the earlier findings or to discover and explore sites that are not accessible to robotic spacecraft.     

On the levels of enzymatic substrate specificity: implications for the early evolution of metabolic pathways.

The most frequently invoked explanation for the origin of metabolic pathways is the retrograde evolution hypothesis. In contrast, according to the so-called "patchwork" theory, metabolism evolved by the recruitment of relatively inefficient small enzymes of broad specificity that could react with a wide range of chemically related substrates. In this paper it is argued that both sequence comparisons and experimental results on enzyme substrate specificity support the patchwork assembly theory. The available evidence supports previous suggestions that gene duplication events followed by a gradual neoDarwinian accumulation of mutations and other minute genetic changes lead to the narrowing and modification of enzyme function in at least some primordial metabolic pathways.     

Instrumentenentwicklungen für anwendungsaufgaben der fernerkundung photogrammetrie,geophysik und geodäsie

(Instrument Developments for Applications in Remote Sensing, Photogrammetry, Geophysics and Geodesy) The Modular Optoelectronic Multispectral Seanner MOMS-01, a CCD camera using the push-broom scanner principle, is presented in this paper in its flight configuration. This instrument will be the first European-built spaceborne unaging system for remote sensing applications (launch with Shuttle flight No. 7).Follow-on developments of this initial two-channel version are oriented to an extension of capabilities by a panchromatic high-resolution stereoscopic module for thematic mapping and two additional spectral channels in the reflective IR (up to 2.3 μm) offering a high interpretation potential for future earth resources exploration missions. Furthermore the subjects of advanced laser technology studies are introduced: A picosecond pulse laser system for detection of tectonic motions and for geodetic application, a CO laser for ultra precise range rate determination (Earth potential and Geoid) and a laser range finder for intersatellite distance measurements.     

International cooperation in assuring continuity of environmental satellite data

In the 25 years since the launch of the first weather satellite, meteorological observations from space have become an essential part of weather forecasting and global environmental monitoring. Beginning in the 1970s, constrained national budgets and the need for a coordinated approach to global satellite observing have caused satellite operators to pursue international cooperation to assure the continuity and compatibility of these systems. This article reviews current bilateral and multilateral cooperation and technical coordination in environmental satellite activities. It also explores the potential for alternative institutional arrangements for maintaining the continuity of environmental satellite data in the decades to come.     

A new method of determining the spectral index for protons in the energy range about 10<Superscript>13</Superscript> eV

We consider a relationship between the difference in spectral indices of the spectra of single hadrons and all hadrons (_sngl – _h) and the difference in the indices of the spectra of galactic cosmic ray (GCR) protons and nuclei. It is demonstrated that at the mountain level the ratio (_p – _Z)/(_sngl – _h) is always larger than unity, if (_sngl – _h) > 0.1. From the experimental value _sngl – _h = 0.4 ± 0.05 we derive that, in the vicinity of E = 10 TeV, _p – _Z 0.49 ± 0.06 , i.e., _p 3.09 ± 0.06.__________Translated from Kosmicheskie Issledovaniya, Vol. 43, No. 2, 2005, pp. 83–87.Original Russian Text Copyright © 2005 by Grigorov, Tolstaya.     

Order of magnitude analysis of convective effects in dendritic solidification

The different types of convective phenomena which may occur during the dendritic solidification of metallic alloys are discussed from an order of magnitude analysis. Bulk thermal convection and/or interdendritic solutal convection have to be considered according to the values of the experimental data. Scaling laws for the solute boundary layer resulting from bulk thermal convection have already been derived. It is shown here that the interdendritic flow depends on a solutal Grashof number Gr based on the horizontal density gradient and a characteristic length L_s which is of the order of the liquid channels width. For Gr < 1, which is generally verified in practical cases, the interdendritic flow velocity U_r is proportional to the Grashof number. This a priori law compares favorably with the results of horizontal solidification experiments where the mean interdendritic flow velocity has been estimated from the resulting measured macrosegregation. In these experiments, as well as for most horizontal dendritic solidifications of metallic alloys at 1 g, the ratio $\text{U}{}_{\mathrm{r}}\text{R}$ (R is the growth rate) is of order one. In order to cancel the interdendritic flow effects, this ratio has to be lowered by one order of magnitude. According to our analysis, this can be obtained by performing the experiments either at a slightly reduced g level (～10^?1 g), or at 1 g in a vertical stable configuration with a sufficiently low residual horizontal thermal gradient.