Choroidal responses in microgravity. (SLS-1, SLS-2 and hindlimb-suspension experiments)

Fluid and electrolyte shifts occuring during human spaceflight have been reported and investigated at the level of blood, cardio-vascular and renal responses. Very few data were available concerning the cerebral fluid and electrolyte adaptation to microgravity, even in animal models. It is the reason why we developed several studies focused on the effects of spaceflight (SLS-1 and SLS-2 programs, carried on NASA STS 40 and 56 missions, which were 9- and 14-day flights, respectively), on structural and functional features of choroid plexuses, organs which secrete 70–90 % of cerebrospinal fluid (CSF) and which are involved in brain homeostasis. Rats flown aboard space shuttles were sacrificed either in space (SLS-2 experiment, on flight day 13) or 4–8 hours after landing (SLS-1 and SLS-2 experiments). Quantitative autoradiography performed by microdensitometry and image analysis, showed that lateral and third ventricle choroid plexuses from rats flown for SLS-1 experiment demonstrated an increased number (about x 2) of binding sites to natriuretic peptides (which are known to be involved in mechanisms regulating CSF production). Using electron microscopy and immunocytochemistry, we studied the cellular response of choroid plexuses, which produce cerebrospinal fluid (CSF) in brain lateral, third and fourth ventricles. We demonstrated that spaceflight (SLS-2 experiment, inflight samples) induces changes in the choroidal cell structure (apical microvilli, kinocilia organization, vesicle accumulation) and protein distribution or expression (carbonic anhydrase II, water channels,…). These observations suggested a loss of choroidal cell polarity and a decrease in CSF secretion. Hindlimb-suspended rats displayed similar choroidal changes. All together, these results support the hypothesis of a modified CSF production in rats during long-term (9, 13 or 14 days) adaptations to microgravity.     

Energetic Particles Investigation (EPI)

The Energetic Particles Investigation (EPI) instrument operates during the pre-entry phase of the Galileo Probe. The major science objective is to study the energetic particle population in the innermost regions of the Jovian magnetosphere — within 4 radii of the cloud tops — and into the upper atmosphere. To achieve these objectives the EPI instrument will make omnidirectional measurements of four different particle species — electrons, protons, alpha-particles, and heavy ions (Z > 2). Intensity profiles with a spatial resolution of about 0.02 Jupiter radii will be recorded. Three different energy range channels are allocated to both electrons and protons to provide a rough estimate of the spectral index of the energy spectra. In addition to the omnidirectional measurements, sectored data will be obtained for certain energy range electrons, protons, and alpha-particles to determine directional anisotropies and particle pitch angle distributions. The detector assembly is a two-element telescope using totally depleted, circular silicon surfacebarrier detectors surrounded by a cylindrical tungsten shielding with a wall thickness of 4.86 g cm^-2. The telescope axis is oriented normal to the spherical surface of the Probe's rear heat shield which is needed for heat protection of the scientific payload during the Probe's entry into the Jovian atmosphere. The material thickness of the heat shield determines the lower energy threshold of the particle species investigated during the Probe's pre-entry phase. The EPI instrument is combined with the Lightning and Radio Emission Detector (LRD) such that the EPI sensor is connected to the LRD/EPI electronic box. In this way, both instruments together only have one interface of the Probe's power, command, and data unit.     

Broadening of Fe X (6374 Å) profiles above the limb in a coronal hole

Profiles of the visible Fe X (6374 Å) coronal emission line as a function of height above the limb were obtained out to 1.16 solar radii in a coronal hole using the NSO/Sacramento Peak Observatory Coronagraph, Universal Spectrograph and a CCD camera. These are the first coronal line profiles obtained as a function of height in a coronal hole from the ground. Analysis of the line widths suggests a large component of nonthermal broadening which increases with height ranging from 40 to 60 km/s, depending upon the assumed temperature or thermal component of the profile.     

Coronal Observations of CMEs

CMEs have been observed for over 30 years with a wide variety of instruments. It is now possible to derive detailed and quantitative information on CME morphology, velocity, acceleration and mass. Flares associated with CMEs are observed in X-rays, and several different radio signatures are also seen. Optical and UV spectra of CMEs both on the disk and at the limb provide velocities along the line of sight and diagnostics for temperature, density and composition. From the vast quantity of data we attempt to synthesize the current state of knowledge of the properties of CMEs, along with some specific observed characteristics that illuminate the physical processes occurring during CME eruption. These include the common three-part structures of CMEs, which is generally attributed to compressed material at the leading edge, a low-density magnetic bubble and dense prominence gas. Signatures of shock waves are seen, but the location of these shocks relative to the other structures and the occurrence rate at the heights where Solar Energetic Particles are produced remains controversial. The relationships among CMEs, Moreton waves, EIT waves, and EUV dimming are also cloudy. The close connection between CMEs and flares suggests that magnetic reconnection plays an important role in CME eruption and evolution. We discuss the evidence for reconnection in current sheets from white-light, X-ray, radio and UV observations. Finally, we summarize the requirements for future instrumentation that might answer the outstanding questions and the opportunities that new space-based and ground-based observatories will provide in the future.     

Analysis of nonstationary heating and cooling of a thermomagnetic engine gadolinium working element

The paper presents the results of calculating nonstatitionary heat exchange between a heattransfer agent (water) and a gadolinium working element of the thermomagnetic engine with the use of ANSYS 13.0 certified software. Recommendations for designing the thermomagnetic engine working elements are given based on the analysis of calculation results.     

Aircraft engine health management via stochastic modelling of flight data interrelations

A novel engine health management (EHM) scheme is introduced. It uses flight-level, instead of thermodynamic, data to cost-effectively augment the onboard EHM redundancy. For a nominal healthy aircraft, fault-sensitive interrelations among flight data are globally modelled inside a flight regime via Constant-Coefficient Pooled Nonlinear AutoRegressive with eXogenous (CCP-NARX) excitation representations. Single or sequential engine faults perturb these interrelations. Statistically evaluating the perturbation-induced effects draws reliable conclusions on the engine?s health. Validation and comparisons with Kalman filter-based alternatives are made throughout the regime under various operational conditions.     

EUVITA — An extreme UV imaging telescope array with spectral capability

EUVITA is a set of 8 extreme UV normal incidence imaging telescopes, each of them sensitive in a narrow band (λ/Δλ = 15 to 80), centered at wavelengths between 50 and 175 Å. Each telescope has an effective area of a few cm²; a field of view of 1.2° and a spatial resolution of 10 arcsec.

EUVITA will be flown on the Russian mission SPECTRUM X-G. This satellite will be launched in a highly eccentric orbit with a period of 4 days, allowing long, uninterrupted observations (e.g. 10⁵ seconds). EUVITA's narrow spectral bands allow the measurement of source parameters such as temperature or power law index as well as interstellar absorption, and will resolve groups of strong lines emitted by optically thin hot plasmas.     

Force sensitivity of plant gravisensing.

Rotation at 4, 10, 50 and 100 rpm on a horizontal clinostat and in microgravity exerts limited effects on the morphogenesis of lettuce and cress root statocytes and statoliths if compared with the vertical control or 1 g spaceflight reference centrifuge. However, the average distance of statoliths from the distal wall increases. The pattern of plastid location of microgravity-grown and that of clino-rotated samples has been determined at 10, 50, and 100 rpm. Experiments on the centrifuge-clinostat and spaceflight centrifuge (acceleration forces of 0.005 to 1 g) revealed that the average statolith location depends on the amplitude of acropetally or basipetally directed mass acceleration. Decreasing the acropetally directed force from 1 g to 0.4 g dislocates statoliths towards the cell center possibly mediated by the elastic forces of the cytoskeleton. In statocytes formed on the clinostat or in microgravity, the majority of statoliths are located at the center of the cell. To force the statoliths from the center of the statocyte towards one of its poles, a threshold mass acceleration of 0.01 g is required. Statocytes with centrally-located statoliths are considerably more effective in transducing a gravistimulus than those with distally-located plastids. The latent time of the graviresponse is shorter and the response itself is enhanced in roots grown on the clinostat compared to vertically grown samples. The early phases of graviperception are independent of root growth conditions since presentation time and g-threshold are similar for roots grown stationary and those on a clinostat. We propose a sequence of events in gravitropic stimulation that considers not only the lateral displacement of statoliths, as predicted by the starch-statolith hypothesis, but also its longitudinal motion, together with differential gravisensitivity of mechanotransducing structures along the lower-most longitudinal cell wall.     

Microgravity and the organisms: results of the Spacelab mission D1.

During the Spacelab mission D1 different organisms were investigated at the unicellular and multicellular level respectively. Microgravity affects growth and development of the organisms in a different manner, some processes are enhanced, others are inhibited. On the other hand, there are a lot of parameters. e.g. circadian rhythm or cell and organ polarity, which seem to be exclusively under genetical control.     

Accessing NASA technology with the World Wide Web

NASA Langley Research Center (LaRC) began using the World Wide Web (WWW) in the summer of 1993, becoming the first NASA installation to provide a center-wide home page. This coincided with a reorganization of LaRC to provide a more concentrated focus on technology transfer to both aerospace and non-aerospace industry. Use of WWW and NCSA Mosaic not only provides automated information dissemination, but also allows for the implementation, evolution and integration of many technology transfer and technology awareness applications. This paper describes several of these innovative applications, including the on-line presentation of the entire Technology Opportunities Showcase (TOPS), an industrial partnering showcase that exists on the Web long after the actual 3-day event ended. The NASA Technical Report Server (NTRS) provides uniform access to many logically similar, yet physically distributed NASA report servers. WWW is also the foundation of the Langley Software Server (LSS), an experimental software distribution system which will distribute LaRC-developed software. In addition to the more formal technology distribution projects, WWW has been successful in connecting people with technologies and people with other people