Life sciences flight hardware development for the International Space Station.

During the construction phase of the International Space Station (ISS), early flight opportunities have been identified (including designated Utilization Flights, UF) on which early science experiments may be performed. The focus of NASA's and other agencies' biological studies on the early flight opportunities is cell and molecular biology; with UF-1 scheduled to fly in fall 2001, followed by flights 8A and UF-3. Specific hardware is being developed to verify design concepts, e.g., the Avian Development Facility for incubation of small eggs and the Biomass Production System for plant cultivation. Other hardware concepts will utilize those early research opportunities onboard the ISS, e.g., an Incubator for sample cultivation, the European Modular Cultivation System for research with small plant systems, an Insect Habitat for support of insect species. Following the first Utilization Flights, additional equipment will be transported to the ISS to expand research opportunities and capabilities, e.g., a Cell Culture Unit, the Advanced Animal Habitat for rodents, an Aquatic Facility to support small fish and aquatic specimens, a Plant Research Unit for plant cultivation, and a specialized Egg Incubator for developmental biology studies. Host systems (Figure 1A, B: see text), e.g., a 2.5 m Centrifuge Rotor (g-levels from 0.01-g to 2-g) for direct comparisons between g and selectable g levels, the Life Sciences Glovebox for contained manipulations, and Habitat Holding Racks (Figure 1B: see text) will provide electrical power, communication links, and cooling to the habitats. Habitats will provide food, water, light, air and waste management as well as humidity and temperature control for a variety of research organisms. Operators on Earth and the crew on the ISS will be able to send commands to the laboratory equipment to monitor and control the environmental and experimental parameters inside specific habitats. Common laboratory equipment such as microscopes, cryo freezers, radiation dosimeters, and mass measurement devices are also currently in design stages by NASA and the ISS international partners.     

Ground performance of air conditioning and water recycle system for a Space Plant Box.

Researchers from 5 Japanese universities have developed a plant growth facility (Space Plant Box) for seed to seed experiments under microgravity. The breadboard model of the Space Plant Box was fabricated by assembling subsystems developed for microgravity. The subsystems include air conditioning and water recycle system, air circulation system, water and nutrient delivery system, lighting system and plant monitoring system. The air conditioning and water recycle system is simply composed of a single heat exchanger, two fans and hydrophilic fibrous strings. The strings allow water movement from the cooler fin in the Cooling Box to root supporting materials in the Plant Growth Chamber driven by water potential deficit. Relative humidity in the Plant Growth Chamber can be changed over a wide range by controlling the ratio of latent heat exchange to sensible heat exchange on the cooling fin of the heat exchanger. The transpiration rate was successfully measured by circulating air inside the Plant Growth Chamber only. Most water was recycled and a small amount of water needed to be added from the outside. The simple, air conditioning and water recycle system for the Space Plant Box showed good performance through a barley (Hordeum vulgare L.) growth experiment.     

Imaging the solar corona in the EUV

The SOHO (SOlar and Heliospheric Observatory) satellite was launched on December 2nd 1995. After arriving at the Earth-Sun (L1) Lagrangian point on February 14th 1996, it began to continuously observe the Sun. As one of the instruments onboard SOHO, the EIT (Extreme ultraviolet Imaging Telescope) images the Sun's corona in 4 EUV wavelengths. The He II filter at 304 Å images the chromosphere and the base of the transition region at a temperature of 5 − 8 × 10⁴ K; the Fe IX–X filter at 171 Å images the corona at a temperature of 1.3 × 10⁶ K; the Fe XII filter at 195 Å images the quiet corona outside coronal holes at a temperature of 1.6 × 10⁶ K; and the Fe XV filter at 284 Å images active regions with a temperature of 2.0 × 10⁶ K. About 5000 images have been obtained up to the present. In this paper, we describe also some aspects of the telescope and the detector performance for application in the observations. Images and movies of all the wavelengths allow a look at different phenomena present in the Sun's corona, and in particular, magnetic field reconnection.     

Dynamic considerations for control of closed life support systems

Reliability of closed life support systems will depend on their ability to continue supplying the crew's needs in the face of perturbations and equipment failures. These dynamic considerations interact with the basic static (equilibrium) design through the sizing of storages, the specification of excess capacities in processors, and the choice of system initial state (total mass in the system). This paper uses a very simple system flow model to examine the possibilities for system failures even when there is sufficient storage to buffer the immediate effects of the perturbation. Two control schemes are shown which have different dynamic consequences in response to component failures.     

Advanced regenerative environmental control and life support systems: Air and water regeneration

Extended manned space missions will require regenerative life support techniques. Past U.S. manned missions used nonregenerative expendables, except for a molecular sieve-based carbon dioxide removal system aboard Skylab. The resupply penalties associated with expendables becomes prohibitive as crew size and mission duration increase. The U.S. Space Station, scheduled to be operational in the 1990's, is based on a crew of four to sixteen and a resupply period of 90 days or greater. It will be the first major spacecraft to employ regenerable techniques for life support. The paper uses the requirements for the Space Station to address these techniques.     

The influence of gravity on the structure and functions of plant material

Growth process generate plant form and relate to most physiological functions. The Earth's gravity force affects plant growth in both obvious and subtle ways. It is a major environmental influence on morphology and physiology of plants. Gravity is less important as an agent for plant stress than as an environmental signal to guide growth. The plant's bioaccelerometers are remarkably sensitive, especially in hypogravity. Simulation (clinostat) studies and experiments in satellite laboratories are needed to understand the sensing, transduction, and response characteristics of g related mechanisms. By examining how plants alter growth processes to accomplish developmental or physiological “objectives” we may find it pragmatically desirable to ask ourselves how we might design a plant to achieve such responses to environmental influences. Examples of this design engineering approach for gravity related effects are described as an aid to experimentation.     

New multifrequency measurements of the spectrum of the cosmic background radiation

New measurements of the Cosmic Background Radiation temperature at 12 cm, 6.3 cm, 3 cm, 0.9 cm and 0.3 cm have made in July 1982 from the White Mountain High Altitude Research Station. The results are presented and the existence of spectral distortions discussed.     

On the levels of enzymatic substrate specificity: implications for the early evolution of metabolic pathways.

The most frequently invoked explanation for the origin of metabolic pathways is the retrograde evolution hypothesis. In contrast, according to the so-called "patchwork" theory, metabolism evolved by the recruitment of relatively inefficient small enzymes of broad specificity that could react with a wide range of chemically related substrates. In this paper it is argued that both sequence comparisons and experimental results on enzyme substrate specificity support the patchwork assembly theory. The available evidence supports previous suggestions that gene duplication events followed by a gradual neoDarwinian accumulation of mutations and other minute genetic changes lead to the narrowing and modification of enzyme function in at least some primordial metabolic pathways.     

The chemical profiles of polar ice on Earth and Mars: What we read from the first; what we could read from the second

An analogy is drawn between the current knowledge on terrestrial snow and ice-cap chemistry and the possible composition of snowfall and ice caps of Mars. Terrestrial snowfall reflects the composition of the Earth's atmosphere. Snow cover further interacts with the atmosphere and is the recipient of aerosol and particulate fall-out. The snow is transformed to firn and ice and the chemical signatures become locked into the perennial ice sheets. The chemical profiles of ice thus constitute environmental records of the Earth's past. By considering the present knowledge on the hydrologie cycle of Mars and the chemistry of the atmosphere, a simple analogous model for the chemical profile of the North polar ice cap is proposed. Three major constituents of the ice are discussed: water ice, dust, and occluded air bubbles. The seasonal fluctuations and interannual variability of these components are examined as possible chemical signatures for the dating of ice, elucidating hydrologie processes, and recording long-term climatic change. The model of the north polar cap in summer consists of water-ice fine-dust layers (30–200 m thick) sandwiched between annual dust layers of variable size distribution and thickness (< 1m– > 66 m). The water ice is subjected to metamorphism and grain growth. The interpretation of the physico-chemical profile could lead to increased knowledge on the recent climatic past (1,000–2,000 years), hydrologic reservoirs, and seasonal cycles in the atmospheric dynamics of the planet.     

Organization, selection, and training of crews for extended spaceflight: findings from analogs and implications

Ample research evidence from space analogs points to the crucial role that teamwork plays in the performance of small groups in isolation and confinement. This paper surveys findings about the impacts of group behavior and social interaction on crew morale, coordination, and productivity. Implications for the organization, selection, and training of crews for extended spaceflight are discussed.