Adsorption of amino acids (ALA, CYS, HIS, MET) on zeolites: fourier transform infrared and Raman spectroscopy investigations

Minerals adsorb more amino acids with charged R-groups than amino acids with uncharged R-groups. Thus, the peptides that form from the condensation of amino acids on the surface of minerals should be composed of amino acid residues that are more charged than uncharged. However, most of the amino acids (74%) in today's proteins have an uncharged R-group. One mechanism with which to solve this paradox is the use of organophilic minerals such as zeolites. Over the range of pH (pH 2.66-4.50) used in these experiments, the R-group of histidine (His) is positively charged and neutral for alanine (Ala), cysteine (Cys), and methionine (Met). In acidic hydrothermal environments, the pH could be even lower than those used in this study. For the pH range studied, the zeolites were negatively charged, and the overall charge of all amino acids was positive. The conditions used here approximate those of prebiotic Earth. The most important finding of this work is that the relative concentrations of each amino acid (X=His, Met, Cys) to alanine (X/Ala) are close to 1.00. This is an important result with regard to prebiotic chemistry because it could be a solution for the paradox stated above. Pore size did not affect the adsorption of Cys and Met on zeolites, and the Si/Al ratio did not affect the adsorption of Cys, His, and Met. ZSM-5 could be used for the purification of Cys from other amino acids (Student-Newman-Keuls test, p<0.05), and mordenite could be used for separation of amino acids from each other (Student-Newman-Keuls test, p<0.05). As shown by Fourier transform infrared (FT-IR) spectra, Ala interacts with zeolites through the [Formula: see text] group, and methionine-zeolite interactions involve the COO, [Formula: see text], and CH(3) groups. FT-IR spectra show that the interaction between the zeolites and His is weak. Cys showed higher adsorption on all zeolites; however, the hydrophobic Van der Waals interaction between zeolites and Cys is too weak to produce any structural changes in the Cys groups (amine, carboxylic, sulfhydryl, etc.); thus, the FT-IR and Raman spectra are the same as those of solid Cys.     

Analytical solutions for the relative motion of spacecraft subject to Lorentz-force perturbations

A spacecraft capable of producing higher-than-natural electrostatic charges may achieve propellantless orbital maneuvering via the Lorentz-force interaction with a planetary magnetic field. Development of maneuver strategies for these propellantless vehicles is complicated by the fact that the perturbative Lorentz force acts along only a single line of action at any instant. Relative-motion dynamical models are developed that lead to approximate analytical solutions for the motion of charged spacecraft subject to the Lorentz force. These solutions indicate that the principal effects of the Lorentz force on a spacecraft in a circular orbit are to change the intrack position and to change the orbit plane. A rendezvous example is presented in which a spacecraft with a specific charge of ?3.81 $\times$ 10^?4 C/kg reaches a target vehicle initially 10 km away (on the same equatorial low-Earth orbit) in 1 day. Fly-around maneuvers may be achieved in low-Earth orbit with specific charges on the order of 0.001 C/kg.     

Harnessing functional food strategies for the health challenges of space travel—Fermented soy for astronaut nutrition

Astronauts face numerous health challenges during long-duration space missions, including diminished immunity, bone loss and increased risk of radiation-induced carcinogenesis. Changes in the intestinal flora of astronauts may contribute to these problems. Soy-based fermented food products could provide a nutritional strategy to help alleviate these challenges by incorporating beneficial lactic acid bacteria, while reaping the benefits of soy isoflavones. We carried out strain selection for the development of soy ferments, selecting strains of lactic acid bacteria showing the most effective growth and fermentation ability in soy milk (Streptococcus thermophilus ST5, Bifidobacterium longum R0175 and Lactobacillus helveticus R0052). Immunomodulatory bioactivity of selected ferments was assessed using an in vitro challenge system with human intestinal epithelial and macrophage cell lines, and selected ferments show the ability to down-regulate production of the pro-inflammatory cytokine interleukin-8 following challenge with tumour necrosis factor-alpha. The impact of fermentation on vitamin B1 and B6 levels and on isoflavone biotransformation to agluconic forms was also assessed, with strain variation-dependent biotransformation ability detected. Overall this suggests that probiotic bacteria can be successfully utilized to develop soy-based fermented products targeted against health problems associated with long-term space travel.     

基于精确伪距率观测模型的GPS/SINS组合导航系统研究

从泰勒公式及函数矩阵的基本定义出发，推导了考虑位置误差相关项时，GPS/SINS组合导航系统精确的伪距率观测数学模型。仿真结果表明，使用精确伪距率观测模型的伪距、伪距率交替组合导航系统，其位置误差能更好地跟踪GPS系统位置几何误差系数，能更真实地反映载体的短期位置误差，更适用于对航天器或大气飞行器短期位置导航精度要求较高的场合（如把航天飞机或大气飞行器作为高分辨率合成孔径雷达等遥感器的载体）。     

The challenges and opportunities of a commercial human spaceflight mission to the ISS

ESA astronauts' ISS flight opportunities are considered as a vital source to meet the utilisation, operation and political objectives that Europe has established for participating in the International Space Station programme. Recent internal ESA assessments have demonstrated that a rate of three flights per year for European Astronauts should be maintained as a minimum objective. The current flight rate is lower than this. In order to improve this situation, in the context of the activation of the ESA ISS Commercialisation programme, ESA is developing the conditions for the establishment of commercially based human spaceflights with the financial support of both ESA and the private sector or, in the future, only the latter. ESA is working in a Partnership with the space industry to facilitate the implementation of such projects and support customers with a range of end-to-end commercial services. The opportunities and challenges of a "commercial human spaceflight", involving a member of the European Astronaut Corps, or a privately employed flight participant, are discussed here.     

ESA developments in life support technology: achievements and future priorities.

Following an enthusiastic start in 1985, ESA's life support technology development programme was re-assessed in the mid- to late-1990s to reflect the strong reduction in European manned space ambitions which occurred at that time. Further development was essentially restricted to activities that could constitute ISS upgrades or enhancements, or support ISS utilisation/operations, together with a single, limited, activity (MELISSA) aimed at bioregenerative life support, in the continuing hope that there might be "life after Station". The paper describes the current status of these activities and summarises the main priorities for future development that were identified at the April 1999 Workshop on Advanced Life Support.     

Cave biosignature suites: microbes,minerals, and Mars

Earth's subsurface offers one of the best possible sites to search for microbial life and the characteristic lithologies that life leaves behind. The subterrain may be equally valuable for astrobiology. Where surface conditions are particularly hostile, like on Mars, the subsurface may offer the only habitat for extant lifeforms and access to recognizable biosignatures. We have identified numerous unequivocally biogenic macroscopic, microscopic, and chemical/geochemical cave biosignatures. However, to be especially useful for astrobiology, we are looking for suites of characteristics. Ideally, "biosignature suites" should be both macroscopically and microscopically detectable, independently verifiable by nonmorphological means, and as independent as possible of specific details of life chemistries--demanding (and sometimes conflicting) criteria. Working in fragile, legally protected environments, we developed noninvasive and minimal impact techniques for life and biosignature detection/characterization analogous to Planetary Protection Protocols. Our difficult field conditions have shared limitations common to extraterrestrial robotic and human missions. Thus, the cave/subsurface astrobiology model addresses the most important goals from both scientific and operational points of view. We present details of cave biosignature suites involving manganese and iron oxides, calcite, and sulfur minerals. Suites include morphological fossils, mineral-coated filaments, living microbial mats and preserved biofabrics, 13C and 34S values consistent with microbial metabolism, genetic data, unusual elemental abundances and ratios, and crystallographic mineral forms.     

磁扰日向阳面对流电场转向区位置的晨昏不对称性(STARE、TRIAD、AE-C观测综合分析)

本文通过STARE观测的晨不连续性及其与TRIAD观测的场向电流分界区、AE-C卫星观测的电场转向区位置的比较,提出了在高扰日向阳面对流电场转向区位置存在着晨不对称性——晨半面所处纬度低于昏半面.该现象间接说明向阳面磁层边界层也存在某种不对称性.并在观测基础上对可造成该不对称性的物理因子进行了探讨,认为行星际磁场螺线结构对重连区位置的影响及其产生的激波结构的晨昏不对称性很可能与本文中讨论的现象有一定联系.     

Dosimetric mapping inside BIORACK

The experiment was flown in different locations inside BIORACK on the D1 mission. It contained different plastic detectors (cellulose nitrate, Lexan, and CR 39) and emulsions to measure the high LET components of the radiation environment. For low LET measurements thermoluminescence dosimeters (L iF) were used. The paper gives data about total dose, charge, energy, and LET spectra so far obtained. These data are compared with data of previous spaceflights.