Radiation biodosimetry: applications for spaceflight.

The multiparametric dosimetry system that we are developing for medical radiological defense applications could be adapted for spaceflight environments. The system complements the internationally accepted personnel dosimeters and cytogenetic analysis of chromosome aberrations, considered the best means of documenting radiation doses for health records. Our system consists of a portable hematology analyzer, molecular biodosimetry using nucleic acid and antigen-based diagnostic equipment, and a dose assessment management software application. A dry-capillary tube reagent-based centrifuge blood cell counter (QBC Autoread Plus, Becton [correction of Beckon] Dickinson Bioscience) measures peripheral blood lymphocytes and monocytes, which could determine radiation dose based on the kinetics of blood cell depletion. Molecular biomarkers for ionizing radiation exposure (gene expression changes, blood proteins) can be measured in real time using such diagnostic detection technologies as miniaturized nucleic acid sequences and antigen-based biosensors, but they require validation of dose-dependent targets and development of optimized protocols and analysis systems. The Biodosimetry Assessment Tool, a software application, calculates radiation dose based on a patient's physical signs and symptoms and blood cell count analysis. It also annotates location of personnel dosimeters, displays a summary of a patient's dosimetric information to healthcare professionals, and archives the data for further use. These radiation assessment diagnostic technologies can have dual-use applications supporting general medical-related care.     

Planetarium Inversum -- a space vision for Earth education.

In a planetarium, the visitor is sitting on Earth and looking into an imaginary space. The Planetarium Inversum is the opposite: visitors are sitting in a space station, looking down on Mother Earth. It is a scientifically-based information show with visitors involvement, its elements being partially virtual (Earth in space has to be projected with highest possible resolution) but also containing real structures, such as the visitors' Earth observatory with adjacent biological systems (plant cultures and other ecological life support components). Its main message concerns the limits and the vulnerability of our home planet, its uniqueness, beauty and above all, its irreplaceableness: Earth does not have an emergency exit. The Earth observatory is part of a ring shaped, rotating space station of the type designed by Wernher von Braun decades ago. Visitors are told that gravity is being substituted by centrifugal force. Both types of life support systems are being demonstrated--self regenerative life based ones and technical ones as a backup (solar electric splitting of water and chemical absorption of respiratory CO2).     

Development of a Digital Array Radar (DAR)

Twenty-first century littoral and open-sea missions present US Navy (USN) shipboard-radar systems with the challenge of detecting small targets in severe clutter and against multiple sources of interference. In Fiscal Year 2000 (FY00), the Office of Naval Research (ONR) sponsored a program to develop an active array radar that includes a digital beamforming (DBF) architecture. The DBF radar system has the potential for improved time-energy management, improved signal-to-clutter (S/C) ratios, improved reliability and reduced life-cycle costs. This paper summarizes the latest developments of the program during FY00     

Next generation digital GPS receiver

The architecture and technology features of the next-generation (NGR) digital GPS (Global Positioning System) receiver manufactured by Collin are described. The project's objective was to develop an advanced GPS receiver chipset with high antijam capabilities. The program, initiated in 1985, has provided the technology for miniature receiver products for both unmanned and manned vehicle applications. A two-channel version of the receiver is in full-scale development for tactical missile applications. A five-channel version is being tested and evaluated as a drop-in replacement for RCVR-3A, the US Department of Defense standard high dynamic receiver. The NGR design started with the digital signal processing architecture developed for the Defense Advanced Research Project Agency (DARPA) hand-held GPS receiver. Enhancements were made to improve the antijam and signal acquisition performance. Producible, qualifiable and cost-effective silicon monolithic microwave integrated circuits and semicustom digital technologies were used to develop the core GPS chipset. A system design approach was established to permit reuse of mature and validated GPS software     

Factors influencing the heating of the auroral electrojet by high power radio waves

Results are presented from recent ionospheric modification experiments in which the EISCAT UHF radar measured the E-region temperature and density response to high power RF heating above Tromsø. A variety of electrojet conditions were encountered during these experiments. In particular, the electron drift velocity varied considerably allowing the heating efficiency of the RF heater to be investigated as a function of electron flow velocity. These observations constitute the first direct investigation of electrojet temperature modifications by high power radio waves and provide a test of a recent theoretical model in which the combined effects of RF heating and of natural plasma turbulence associated with the Farley-Buneman instability have been considered.     

A high performance automotive radar for automatic AICC

The paper describes a recent effort to design, build, and test a 77 GHz radar to be used for “intelligent” cruise control of automobiles. An analysis of requirements is given, design trade-offs are accounted for, and main features of prototypes in manufacturing are detailed. The radar has been thoroughly tested and evaluated both under “controlled” conditions and on roads, also in dense traffic. Results so far are very promising     

Neuritogenesis: a model for space radiation effects on the central nervous system.

Pivotal to the astronauts' functional integrity and survival during long space flights are the strategies to deal with space radiations. The majority of the cellular studies in this area emphasize simple endpoints such as growth related events which, although useful to understand the nature of primary cell injury, have poor predictive value for extrapolation to more complex tissues such as the central nervous system (CNS). In order to assess the radiation damage on neural cell populations, we developed an in vitro model in which neuronal differentiation, neurite extension, and synaptogenesis occur under controlled conditions. The model exploits chick embryo neural explants to study the effects of radiations on neuritogenesis. In addition, neurobiological problems associated with long-term space flights are discussed.     

The observation of the galactic anticenter region by the balloon borne gamma-ray telescope Natalya-I

This paper presents the results of measurements of gamma radiation with energies above 5 MeV, from the galactic anticenter region. The balloon-borne gamma ray telescope “Natalya-I”, was launched on 6 November, 1980 from the Tata Institute of Fundamental Research's Balloon Facility (Hyderabad, India) and reached ceiling altitude of 35 km. The results on the accelerator calibration of the telescope, using a “tagged” gamma ray beam are also presented.     

A critical look at space technology and the developing world

Technology is neutral, its use is not. Its introduction and use take place in social, cultural, political and economic contexts which can be at considerable variance with those of the introducing countries, and which are not homogeneous within countries having wide variations in knowldege, background skills, and interpretations of meaning and opportunity.This paper tries to take a dispassionate look at the social and cultural factors that are involved in the introduction, use, and maintenance of space technology in the developing world.