The role of repair in the survival of mammalian cells from heavy ion irradiation: approximation to the ideal case of target theory.

Theories of cellular radiation sensitivity that preclude a significant role for cellular repair processes in the final biological expression of cellular damage induced by ionizing radiation are unsound. Experiments are discussed here in which the cell-cycle dependency of the repair deficiency of the S/S variant, of the L5178Y murine leukemic lymphoblast was examined by treatment with the heavy ions, 20Ne, 28Si, 40Ar, 56Fe and 93Nb. Evidence from those studies, which will be described in detail elsewhere, provide support for the notion that as the linear energy transfer (LET infinity) of the incident radiation increases the ability of the S/S cell to repair radiation damage decreases until effectively it is eliminated around 500 keV/micrometer. In the region of the latter LET infinity value, the behavior of the S/S cell approximates the ideal case of target theory where post-irradiation metabolism (repair) does not influence cell survival. The expression of this phenomenon among different cell types and tissues will depend upon the actual repair systems involved and other considerations.     

Risk-taking during wayfinding is modulated by external stressors and personality traits

ABSTRACT

Two experiments examined cue reliance and risk-taking during desktop virtual wayfinding, and how they might be modulated by personality traits and external stressors. Participants navigated a series of virtual buildings and we manipulated the strength of probabilistic cues available to guide turn decisions. Navigators frequently discounted probabilistic cues and instead took risks, particularly when costs were low and potential benefits were high. Risk-taking was predicted by higher sense of direction and lower need for structure. Introducing a time stressor lowered risk-taking, with a higher relative reliance on probability-based information. This was most pronounced in females and those with a high need for structure. Results provide novel evidence that spatial cue reliance is modulated by individual differences and contextual constraints.     

On the arc length of observations of a small solar system body sufficient to classify it as hazardous

This paper analyzes the accuracy of orbit determination calculated by observations of short arcs. In this case, we imposed the condition that the arc length and/or the distribution of arc observations should provide a confident classification of the orbit of a small celestial body allowing one to distinguish a potentially hazardous body, also including a threat of collision.     

Space experiments aboard the Lomonosov MSU satellite

At present, the Institute of Nuclear Physics of Moscow State University, in cooperation with other organizations, is preparing space experiments onboard the Lomonosov satellite. The main goal of this mission is to study extreme astrophysical phenomena such as cosmic gamma-ray bursts and ultra-high-energy cosmic rays. These phenomena are associated with the processes occurring in the early universe in very distant astrophysical objects, therefore, they can provide information on the first stages of the evolution of the universe. This paper considers the main characteristics of the scientific equipment aboard the Lomonosov satellite.     

Symmetric periodic solutions of the Hill’s problem. I

The planar circular Hill’s problem is considered, as well as its limiting integrable variant called the Hénon problem, for which the original Hill’s problem is a singular perturbation. Among solutions to the Hénon problem there are a countable number of generating solutions-arcs that are uniquely determined by the condition of successive passage through the origin of coordinates—singular point of equations of motion of the Hill’s problem. Using the generating solutions-arcs as “letters” of a certain “alphabet”, one can compose, according to some rules, the “words”: generating solutions of families of periodic orbits of the Hill’s problem. The sequence of letters in a word determines the order of orbit transfer from one invariant manifold to another, while the set of all properly specified words determine the system’s symbolic dynamics.     

基于模糊机会约束规划的机会阵雷达方向图综合

针对机会阵雷达方向图综合的不确定问题,提出了一种基于模糊机会约束规划的方向图综合规划模型。该模型基于可信性理论,综合考虑天线单元分布的随机性以及激励状态的不确定性,将参与方向图综合时激励打开的天线数目看做一个梯形模糊变量,用以描述综合时的复杂不确定环境。随后,将规划模型转化为清晰等价形式,再结合遗传算法和灰关联综合评价法则设计了一种混合智能优化算法,用于求解该模型。以一维任意非均匀线阵为例,对主瓣宽度和最大副瓣电平进行了优化。仿真表明:优化后结果的可信性高于置信水平,验证了该算法的有效性。     

Surface Composition of Vesta: Issues and Integrated Approach

The instruments on the Dawn spacecraft are exceptionally well suited to characterize and map the surface composition of Vesta in an integrated manner. These include a framing camera with multispectral capabilities, a high spectral resolution near-infrared imaging spectrometer, and a gamma-ray and neutron spectrometer. Three examples of issues addressed at Vesta are: (1) What is the composition of Vesta??s interior and differentiation state as exposed by the Great South Crater? (2) How has space weathering affected Vesta, both globally and at a local scale? and (3) Are volatiles or hydrated material present on Vesta??s surface? We predict that Dawn finds many surprises, such as an olivine-bearing mantle exposed near the south-pole, a weakly or un-weathered surface that has been relatively recently resurfaced, and a very thin layer of surficial volatiles derived from interaction with the solar wind.     

Energy-efficient intensifiers of laminar heat transfer

In this paper, calculations of some thermo-hydraulic parameters of different intensified channels have been carried out and a grooved channel that is optimal in mass and energy expenditure is determined. A new variant of the intensified channel is proposed and recommendations for engineers are presented.     

Advanced materials for next generation NiMH portable, HEV and EVbatteries

While Ovonic NiMH batteries are already in high volume commercial production for portable applications, advances in materials technology have enabled performance improvements in specific energy (100 Wh/kg), specific power (600-1000 W/kg), high temperature operation, charge retention, and voltage stability. Concurrent with technology advances, Ovonic NiMH batteries have established performance and commercial milestones in electric vehicles, hybrid electric vehicles, as well as scooter, motorcycle and bicycle applications. As important as these advances, significant manufacturing cost reductions have also occurred which allow continued growth of NiMH technology. In this paper, advances in performance, applications and cost reduction are discussed with particular emphasis on the improved proprietary metal hydride and nickel hydroxide materials that make such advances possible     

Reducing Undesirable Effects in the Human Centrifuge

The human centrifuge is used to train pilots and astronauts for flights where they are subject to large accelerations. This paper deals with the problems of simulating such linear accelerations with a rotating device and presents suitable means of reducing undesirable simulation error. The advantages of using three gimbals rather than the usual two are considered. Numerical results illustrate the problems of simulation and the improvement achieved by the use of a third gimbal.