Free radicals induced in solid DNA by heavy ion bombardment.

Free radical formation after heavy-ion bombardment was studied in solid, polycristalline pellets of DNA-constituents by analysing the dose-yield curves and the spectra obtained by ESR-spectroscopy at low (< 100 K) and ambient temperatures. The dose-yield curves were found to correlate with those found after X-irradiation but shifted to higher doses and lower saturation concentrations. The corresponding radical yields (per 100 eV) exhibit values which are one to two orders of magnitudes lower. The structural aspects as revealed from powder ESR-spectra gave a complex inter-relation between substance, LET, dose and irradiation temperature, which is discussed in terms of mechanistic models.     

Galactic cosmic ray transport methods: past, present, and future.

The development of the theory of high charge and energy (HZE) ion transport is reviewed. The basic solution behavior and approximation techniques will be described. An overview of the HZE transport codes currently available at the Langley Research Center will be given. The near term goal of the Langley program is to produce a complete set of one-dimensional transport codes. The ultimate goal is to produce a set of complete three-dimensional codes which have been validated in the laboratory and can be applied in the engineering design environment. Recent progress toward completing these goals is discussed.     

Cognitive deficits induced by 56Fe radiation exposure.

Exposing rats to particles of high energy and charge (e.g., 56Fe) disrupts neuronal systems and the behaviors mediated by them; these adverse behavioral and neuronal effects are similar to those seen in aged animals. Because cognition declines with age, and our previous study showed that radiation disrupted Morris water maze spatial learning and memory performance, the present study used an 8-arm radial maze (RAM) to further test the cognitive behavioral consequences of radiation exposure. Control rats or rats exposed to whole-body irradiation with 1.0 Gy of 1 GeV/n high-energy 56Fe particles (delivered at the alternating gradient synchrotron at Brookhaven National Laboratory) were tested nine months following exposure. Radiation adversely affected RAM performance, and the changes seen parallel those of aging. Irradiated animals entered baited arms during the first 4 choices significantly less than did controls, produced their first error sooner, and also tended to make more errors as measured by re-entries into non-baited arms. These results show that irradiation with high-energy particles produces age-like decrements in cognitive behavior that may impair the ability of astronauts to perform critical tasks during long-term space travel beyond the magnetosphere.     

Mutation induction in human lymphoid cells by energetic heavy ions.

One of the concerns for extended space flight outside the magnetosphere is exposure to galactic cosmic radiation. In the series of studies presented herein, the mutagenic effectiveness of high energy heavy ions is examined using human B-lymphoblastoid cells across an LET range from 32keV/micrometer to 190 keV/micrometer. Mutations were scored for an autosomal locus, thymidine kinase (tk), and for an X-linked locus, hypoxanthine phosphoribosyltransferase (hprt). For each of the radiations studied, the autosomal locus is more sensitive to mutation induction than is the X-linked locus. When mutational yields are expressed in terms of particle fluence, the two loci respond quite differently across the range of LET. The action cross section for mutation induction peaks at 61 keV/micrometer for the tk locus and then declines for particles of higher LET, including Fe ions. For the hprt locus, the action cross section for mutation is maximal at 95 keV/micrometer but is relatively constant across the range from 61 keV/micrometer to 190 keV/micrometer. The yields of hprt-deficient mutants obtained after HZE exposure to TK6 lymphoblasts may be compared directly with published data on the induction of hprt-deficient mutants in human neonatal fibroblasts exposed to similar ions. The action cross section for induction of hprt-deficient mutants by energetic Fe ions is more than 10-fold lower for lymphoblastoid cells than for fibroblasts.     

A program to measure new energetic particle nuclear interaction cross sections.

The Transport Collaboration, consisting of researchers from institutions in France, Germany, Italy and the USA, has established a program to make new measurements of nuclear interaction cross sections for heavy projectiles (Z > or = 2) in targets of liquid H2, He and heavier materials. Such cross sections directly affect calculations of galactic and solar cosmic ray transport through matter and are needed for accurate radiation hazard assessment. To date, the collaboration has obtained data using the LBL Bevalac HISS facility with 20 projectiles from 4He to 58Ni in the energy range 393-910 MeV/nucleon. Preliminary results from the analysis of these data are presented here and compared to other measurements and to cross section prediction formulae.     

Guiding technology development and transition into productsresponsive to end-user needs

It is argued that a systems engineering process that develops an understanding of end-user needs and economically develops a product system which includes the right technology advances to satisfy these needs is the best way to ensure success in the market of end-user needs. This customer pulled approach to new and improved products also pulls the necessary technology developments with it and integrates their timing and resource requirements into those of the end product planning. With appropriate concurrent, cross-functional teams working both the planning and the execution, this approach benefits from the wisdom and leadership of the end-user focused team to deliver the desired program results on schedule. This frees top leadership to focus on longer range visions for the product line and technologies     

A two-dimensional position-sensitive spectroscopic proportional counter for balloon-borne hard X-ray astronomy

A new design of position sensitive spectroscopic proportional counter is described, for use in a balloon borne hard x-ray telescope. Initial position and spectral resolution data from a one-dimensional laboratory prototype are reported. With this device, the final telescope will have an angular resolution of better than 10 minutes of arc.     

Design study for a three-meter balloon-borne telescope for far infrared and submillimeter astronomy

A NASA supported design study is being carried out for a three-meter balloon-borne far infrared and submillimeter telescope. The goal of this project is to provide a facility for frequent flights for photometry, spectroscopy, and imaging in the spectral region 30 micrometers to 1 millimeter. It is intended to provide a scientific and technical step on the way to a large submillimeter telescope in space in the future. The study is concentrating on areas where technical advances are required: materials and fabrication techniques for lightweight primary mirrors, telescope and gondola structure, and pointing and stabilization. We are carrying out a design optimization and environmental test program of state-of-the-art carbon fiber reinforced plastic sandwich panels in collaboration with Dornier Systems. Similar efforts are being pursued for very lightweight molded glass mirrors. Innovative approaches to the telescope support and stabilization are being explored for achieving the required 1 arcsecond pointing stability.     

Investigation of natural and artificial stimulation of the ionospheric Alfvén resonator at high latitude

A brief review is provided of recent progress in understanding the ionospheric Alfvén resonator (IAR) at high latitude. Firstly, naturally occurring resonances of the IAR as detected by pulsation magnetometers in the auroral zone at Sodankylä and in the polar cap at Barentsburg are considered. The characteristics of the IAR in the two regions are broadly similar, although the effects of solar illumination are less clear at the higher latitudes. Secondly we review recent attempts to stimulate the IAR through high-power radio frequency experiments both in the auroral zone at Tromsø with the European Incoherent SCATter (EISCAT) heater, and within the polar cap at Longyearbyen with the Space Plasma Exploration by Active Radar (SPEAR) facility. In the auroral zone at, Tromsø the stimulated IAR has been observed by ground-based magnetometers, and through electron acceleration observed on the FAST spacecraft. At SPEAR in the polar cap, the stimulated IAR has been investigated, with ground magnetometers, with the first results indicative of a positive detection.     

A sample collector for robotic sample return missions III: Impact survivability studies

Laboratory impact tests have been performed on experimental versions of a proposed robotic sample collector for extraterrestrial samples. The collector consists of a retractable aluminum ring containing an impregnable silicone compound that is pressed into the surface of the body to be sampled. As part of a comprehensive program to evaluate this idea, we have performed tests to determine if the samples embedded in the collector medium can survive the impact forces experienced during direct reentry, such as that of the recent Genesis sample return mission. For the present study, samples of sand, rock, glass, and chalk were subjected to decelerations of 1440–2880 g using drop tests. We found that even the most fragile samples, chosen to be representative of a wide range of the types of materials found on the surface of asteroids that have currently been studied, can withstand impacts of the intensity experienced by a sample return capsule during direct reentry.