Clinorotation reduces number, but not size, of cartilaginous nodules formed in micromass cultures of mouse limbbud cells.

In previous studies we used a ground based model to investigate the cellular responses to microgravity by exposing micromass cultures of embryonic limb cells to simulated weightlessness on a clinostat. Cultures set up in T-flasks and rotated at 30 rpm showed that clinostatted cultures had less chondrocyte differentiation than stationary or rotation controls, as assessed by number of nodules/culture stained with cartilage specific Alcian blue. In the current study, nodule size and shape of these nodules was assessed by interactive measurement of area, perimeter, circularity, and equivalent diameters, using the Optimas imaging software. Results show no significant difference in any of the measurements, indicating that clinorotation has no effect on expansion of the nodules either by differentiation of cells within the nodule, or by recruitment of cells into the nodule. The reduction in number of nodules without an alteration in size and shape indicates that the effect of simulated microgravity is to reduce the cell interactions required for the initial condensation of cells into a nodule, probably by interference with cell adhesion molecules.     

Performance limits of sensor-scheduling strategies in electronic support

The case is considered in which a frequency-agile receiver (FAR) for electronic support (ES) attempts to intercept radar emissions over a wide search bandwidth. It was recently shown [1,2] that a random strategy exists in which the expected intercept time can be made arbitrarily close to linear as a function of the scan period of the radar. Can a deterministic strategy be devised in which a similar linear relationship exists for the maximum intercept time? By applying the celebrated arithmetic results of van der Waerden [3] and Szemeredi [4], we show that no such strategy is possible.     

Ion-acoustic waves in unmagnetized collisionless weakly relativistic plasma of warm-ion and isothermal-electron using time-fractional KdV equation

Collisionless unmagnetized plasma consisting of a mixture of warm ion-fluid and isothermal-electron is considered, assuming that the ion flow velocity has a weak relativistic effect. The reductive perturbation method has been employed to derive the Korteweg–de Vries (KdV) equation for small – but finite-amplitude electrostatic ion-acoustic waves in this plasma. The semi-inverse method and Agrawal’s method lead to the Euler–Lagrange equation that leads to the time fractional KdV equation. The variational-iteration method given by He is used to solve the derived time fractional KdV equation. The calculations show that the fractional order may play the same rule of higher order dissipation in KdV equation to modulate the soliton wave amplitude in the plasma system. The results of the present investigation may be applicable to some plasma environments, such as space-plasmas, laser-plasma interaction, plasma sheet boundary layer of the earth’s magnetosphere, solar atmosphere and interplanetary space.