沥青族组分对C/C复合材料热物理性能的影响

以整体碳毡为预制体、两种族组分不同煤沥青为前驱体,采用常压、高压相结合的液相浸渍/炭化技术制备C/C复合材料.研究了复合材料在200～2000℃的热物理性能.结果表明,族组分影响基体碳的微观结构,从而影响材料的热物理性能.煤沥青喹啉不溶物(QI)质量分数高(7.31%),材料的石墨化度为86.29%,真密度为2.13 g/cm3,微观结构为镶嵌型和域型结构为主,并有部分的流线型结构;QI含量低(0.02%),真密度为2.22 g/cm3,其石墨化度达到91.93%,微观结构主要以流线型为主,含有极少量的镶嵌型和域型结构.QI含量越低,复合材料真密度越大,晶体微观结构渐趋完善,石墨片层的有序度增加,石墨化度越高,材料的比热容和导热性能增强,线胀系数降低.     

轴流压气机重复级边界条件的建立及其在流场数值诊断中的应用

本文对轴流压气机多级环境中存在的重复级流动现象的建立及其在流场数值模拟中的应用进行了研究。研究表明负荷是重复级现象建立的关键因素之一,在高负荷的情况下,压气机内很快就可到达重复级状态。另外,本文利用重复级流动模型建立了重复级边界条件,在此基础上,利用1.5 级对流场已达到重复级状态的多级流场进行了流场数值模拟,计算结果表明此方法在保证具有较好精度的前提下。      

复合材料旋翼桨叶剖面扭转刚度计算

本文对Krahula,J.L.等人提出的“圣维南扭转的有限元解”作了合理的改进,使改进后的公式能很方便地编成计算程序,作复合材料旋翼桨叶的扭转刚度计算。还应用改进后的公式计算了两种型号直升机旅翼桨叶的扭转刚度,计算值和试验值有很好的一致性。     

合成孔径雷达在飞行器组合导航系统中的应用

合成孔径雷达(ＳＡＲ)是雷达理论和技术发展到一定阶段的基础上诞生的一种具有很高分辨率的成像雷达。它在众多领域得到了广泛的应用。在飞行器组合导航系统中,利用ＳＡＲ图像进行图像匹配,可以极大地提高系统的导航精度。本文介绍了ＳＡＲ、组合导航系统的发展及研究现状。重点介绍了ＳＡＲ在飞行器组合导航系统中的应用,并给出了具有较高精度、容错性和自主性的ＩＮＳ/ＧＮＳＳ/ＳＡＲ组合导航系统的原理、结构及仿真结果。     

气动伺服弹性综合的应用

在气动伺服弹性技术综合方面开展了如下的研究：气动伺服弹性的建模；控制律的综合设计；自适应控制的可行性；主动控制系统的鲁棒稳定性；以及控制律的工程评估等综合问题。这些问题的讨论，都在同一算例上实施的，实验或计算的结果，都可相互对照比较。     

基于有限元的螺栓弯曲强度分析方法

应用MSC/NASTRAN有限元分析软件,对螺栓弯曲强度进行了分析,通过与工程计算结果的对比,证明有限元模型和有限元分析方法是准确可靠的。     

Simulated microgravity induce apoptosis and down-regulation of erythropoietin receptor of UT-7/EPO cells

Hematopoietic progenitor cell proliferation can be alternated on either spaceflight or under simulated microgravity experiments on the ground; however, the underlying mechanism remains largely unknown. In the present study, we have demonstrated that exposure of human erythropoietin (EPO)-dependent leukemia cell line UT-7/EPO cells to conditions of simulated microgravity with a rotary culture instrument significantly inhibited the cellular proliferation rate. Adding higher concentrations of EPO to the culture medium failed to improve the inhibitory status. Cell apoptosis was detected by fluorescence staining of cell nuclei and a flow cytometry assay using Annexin V/PI double staining. This microgravity-induced apoptosis in UT-7/EPO cells could be blocked by a pancaspase inhibitor Z-VAD-FMK. Immunoblotting demonstrated that rotary culture resulted in a reduction of the expression of Bcl-xL, an anti-apoptotic protein, and the cleavage of caspase-3. Furthermore, rotary culture reduced surface localization and protein content, as well as the mRNA expression of erythropoietin receptor (EPOR) of UT-7/EPO. Take together, the findings indicated that simulated microgravity may induce mitochondrial related apoptosis of UT-7/EPO cell through depressing the EPO–EPOR pathway.     

大型弹簧电镀锌工艺优化

采用扫描电镜(SEM)研究了发蓝、超声波酸洗前处理工艺对大型弹簧零件表面残余氧化皮的去除效果以及这两种前处理工艺对镀锌层的结合力与抗腐蚀性能的影响。结果表明,采用适当的发蓝、超声波酸洗等前处理工艺,能够有效去除零件表面顽固的残余氧化皮,较大幅度地提高镀锌层与金属基体的结合力,并提高镀锌层的抗腐蚀性能。     

高硬度薄壁筒形件数控车加工工艺

以典型零件加工为例,通过探讨高硬度薄壁零件在数控车床加工中存在的易变形、零件尺寸及表面粗糙度不易保证、断续切削时刀具易破损等技术问题,对加工难点进行分析,给出了工艺路线和加工方案,通过优化、完善夹具设计、加工程序和切削参数,使用新型刀具,并打破硬态切削的一些常规做法,从而有效解决高硬度薄壁类零件的车削加工难题。     

Upregulation of erythropoietin receptor in UT-7/EPO cells inhibits simulated microgravity-induced cell apoptosis

Hematopoietic progenitor cell proliferation can be altered in either spaceflight or under simulated microgravity experiments on the ground, however, the underlying mechanism remains unknown. Our previous study showed that exposure of the human erythropoietin (EPO)-dependent leukemia cell line UT-7/EPO to conditions of simulated microgravity significantly inhibited the cellular proliferation rate and induced cell apoptosis. We postulated that the downregulation of the erythropoietin receptor (EPOR) expression in UT-7/EPO cells under simulated microgravity may be a possible reason for microgravity triggered apoptosis. In this paper, a human EPOR gene was transferred into UT-7/EPO cells and the resulting expression of EPOR on the surface of UT-7/EPO cells increased approximately 61% (p < 0.05) as selected by the antibiotic G418. It was also shown through cytometry assays and morphological observations that microgravity-induced apoptosis markedly decreased in these UT-7/EPO–EPOR cells. Thus, we concluded that upregulation of EPOR in UT-7/EPO cells could inhibit the simulated microgravity-induced cell apoptosis in this EPO dependent cell line.