Early effects of low dose C ion or X-ray irradiation on human peripheral blood lymphocytes

The aim of this study was to estimate the acute effects of low dose ¹²C⁶⁺ ions or X-ray radiation on human immune function. The human peripheral blood lymphocytes (HPBL) of seven healthy donors were exposed to 0.05 Gy ¹²C⁶⁺ ions or X-ray radiation and cell responses were measured at 24 h after exposure. The cytotoxic activities of HPBL were determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT); the percentages of T and NK cells subsets were detected by flow cytometry; mRNA expression of interleukin (IL)-2, tumor necrosis factor (TNF)-α and interferon (IFN)-γ were examined by real time quantitative RT-PCR (qRT-PCR); and these cytokines protein levels in supernatant of cultured cells were assayed by enzyme-linked immunosorbent assays (ELISA). The results showed that the cytotoxic activity of HPBL, mRNA expression of IL-2, IFN-γ and TNF-α in HPBL and their protein levels in supernatant were significantly increased at 24 h after exposure to 0.05 Gy ¹²C⁶⁺ ions radiation and the effects were stronger than observed for X-ray exposure. However, there was no significant change in the percentage of T and NK cells subsets of HPBL. These results suggested that 0.05 Gy high linear energy transfer (LET) ¹²C⁶⁺ radiation was a more effective approach to host immune enhancement than that of low LET X-ray. We conclude that cytokines production might be used as sensitive indicators of acute response to LDI.     

卫星控制系统全物理仿真

仿真是应用相似定理和类比关系来研究事物 ,也就是用模型代替实际系统进行实验和研究。在卫星控制系统仿真中 ,根据所介入的模型的不同 ,分为数学仿真和物理仿真两类。卫星控制系统全物理仿真是研制卫星过程中特有的一种仿真方法 ,它利用气浮台作为运动模拟器 ,又称为气浮台仿真。本文主要叙述卫星控制系统全物理仿真的原理和用途 ,简要介绍单轴气浮台和三轴气浮台两个全物理仿真系统的组成、主要设备的技术指标以及卫星控制系统全物理仿真的几个实例     

制样压应力对显微拉曼光谱法获取碳材料结构参数的影响

为了研究金相制样过程中压应力对获取碳材料拉曼特征参数R的影响,对不同温度处理的碳纤维和树脂碳进行了研究.结果表明,制样过程中的压应力对准确获取碳材料的拉曼特征参数具有一定的影响,尤其是对经过高温处理硬度较小的碳材料的影响更大,造成了碳材料R的增大.建议在制备碳材料的显微拉曼光谱测试试样时采用较小的压应力.     

Stifness modeling and analysis of a novel 4-DOF PKM for manufacturing large components

Faster response to orientation varying is one of the outstanding abilities of a parallel kinematic machine（PKM）.It enables such a system to act as a reconfgurable module employed to machine large components effciently.The stiffness formulation and analysis are the beforehand key tasks for its parameters design.A novel PKM with four degrees of freedom（DOFs）is proposed in this paper.The topology behind it is 2PUS-2PRS parallel mechanism.Its semianalytical stiffness model is frstly obtained,where the generalized Jacobian matrix of 2PUS-2PRS is formulated with the help of the screw theory and the stiffness coeffcients of complicated components are estimated by integrating fnite element analysis and numerical ftting.Under the help of the model,it is predicted that the property of system stiffness distributes within the given workspace,which features symmetry about a certain plane and is also verifed by performing fnite element analysis of the virtual prototype.Furthermore,key parameters affecting the system stiffness are identifed through sensitivity analysis.These provide insights for further optimization design of this PKM.     

某型教练机机载天线与雷达罩的射线入射角的计算

随着现代高科技的发展,雷达大量应用于飞机、导弹、航海等领域．雷达罩的运用也日趋广泛。本文通过曲线拟合等一些数学分析方法,运用MATLAB工具,经过分析、编程、计算．最后得到机载天线与雷达罩的射线入射角,通过入射角的大小可判断此雷达罩是否符合要求。     

Fault self-repair strategy based on evolvable hardware and reparation balance technology

In the face of harsh natural environment applications such as earth-orbiting and deep space satellites, underwater sea vehicles, strong electromagnetic interference and temperature stress,the circuits faults appear easily. Circuit faults will inevitably lead to serious losses of availability or impeded mission success without self-repair over the mission duration. Traditional fault-repair methods based on redundant fault-tolerant technique are straightforward to implement, yet their area, power and weight cost can be excessive. Moreover they utilize all plug-in or component level circuits to realize redundant backup, such that their applicability is limited. Hence, a novel selfrepair technology based on evolvable hardware（EHW） and reparation balance technology（RBT） is proposed. Its cost is low, and fault self-repair of various circuits and devices can be realized through dynamic configuration. Making full use of the fault signals, correcting circuit can be found through EHW technique to realize the balance and compensation of the fault output-signals. In this paper, the self-repair model was analyzed which based on EHW and RBT technique, the specific self-repair strategy was studied, the corresponding self-repair circuit fault system was designed, and the typical faults were simulated and analyzed which combined with the actual electronic devices. Simulation results demonstrated that the proposed fault self-repair strategy was feasible. Compared to traditional techniques, fault self-repair based on EHW consumes fewer hardware resources, and the scope of fault self-repair was expanded significantly.     

通用的航电系统总线接口仿真平台的设计和应用

针对当前航电系统仿真器的缺点,提出了一种通用的航电系统总线接口仿真平台的设计思想,通过建立仿真数据库,从待仿真的航电系统设备中的接口信息抽象出属性和行为,然后用数据库的方式来描述,实现了仿真软件和仿真对象的分离,从而使该仿真平台具备了通用性和灵活性。该仿真平台已经在某型机航电系统地面联试中得到了应用。     

一种悬挂物兼容飞机航电与武器总线的设计方法

在某悬挂物作为通用系统挂装不同型号飞机时,由于不同型号飞机对该悬挂物采用航电和武器两种不同的总线通信方式,导致该悬挂物不能兼容挂载多型飞机。本文针对现有的总线应用情况,提出了一种悬挂物可兼容飞机不同总线通信方式的设计方案,并给出了方案的具体实现方法。     

通道不一致对干涉仪测向的影响和解决方法

着重分析了通道不一致对干涉仪测向带来的影响,给出了分析结果,提出了也适用于其它测向系统的解决方法。     

仿真技术在航空推进控制系统中的应用

设计了基于3个层次的航空推进控制系统闭环仿真试验方案,重点阐述了基于试验台的半物理仿真的关键技术。