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81.
Bone loss during long term space flight is prevented by the application of a short term impulsive mechanical stimulus 总被引:2,自引:0,他引:2
In long term space flight, the mechanical forces applied to the skeleton are substantially reduced and are altered in character. This reduced skeletal loading results in a reduction in bone mass. Exercise techniques currently used in space can maintain muscle mass but the mechanical stimulus provided by this exercise does not prevent bone loss. By applying an external impulsive load for a short period each day, which is intended to mimic the heel strike transient, to the lower limb of an astronaut during a long term space flight (5 months), this study tests the hypothesis that the bone cells can be activated by an appropriate external mechanical stimulus to maintain bone mass throughout prolonged periods of weightlessness. A mechanical loading device was developed to produce a loading of the os-calcis similar to that observed during the heel strike transient. The device is activated by the astronaut to provide a transient load to the heel of one leg whilst providing an equivalent exercising load to the other leg. During the EUROMIR95 mission on the MIR space station, an astronaut used this device for a short period daily throughout the duration of the mission. Pre- and post-flight measurements of bone mineral density (BMD) of the os-calcis and femoral neck of the astronaut were made to determine the efficacy of the device in preventing loss of bone mineral during the mission. On the os-calcis which received the mechanical stimulus, BMD was maintained throughout the period of the flight, while it was reduced by up to 7% on the os-calcis which received no stimulus. Post-flight, BMD in both the stimulated and non-stimulated os-calcis reduces, the extent of this reduction however is less in the stimulated os-calcis. For the femoral neck, the mechanical stimulation does not produce a positive effect. 相似文献
82.
83.
The Mercury Atmospheric and Surface Composition Spectrometer (MASCS) is one of seven science instruments onboard the MErcury
Surface, Space ENvironment, GEochemistry, and Ranging (MESSENGER) spacecraft en route to the planet Mercury. MASCS consists
of a small Cassegrain telescope with 257-mm effective focal length and a 50-mm aperture that simultaneously feeds an UltraViolet
and Visible Spectrometer (UVVS) and a Visible and InfraRed Spectrograph (VIRS). UVVS is a 125-mm focal length, scanning grating,
Ebert-Fastie monochromator equipped with three photomultiplier tube detectors that cover far ultraviolet (115–180 nm), middle
ultraviolet (160–320 nm), and visible (250–600 nm) wavelengths with an average 0.6-nm spectral resolution. It will measure
altitude profiles of known species in order to determine the composition and structure of Mercury’s exosphere and its variability
and will search for previously undetected exospheric species. VIRS is a 210-mm focal length, fixed concave grating spectrograph
equipped with a beam splitter that simultaneously disperses the spectrum onto a 512-element silicon visible photodiode array
(300–1050 nm) and a 256-element indium-gallium-arsenide infrared photodiode array 850–1,450 nm. It will obtain maps of surface
reflectance spectra with a 5-nm resolution in the 300–1,450 nm wavelength range that will be used to investigate mineralogical
composition on spatial scales of 5 km. UVVS will also observe the surface in the far and middle ultraviolet at a 10-km or
smaller spatial scale. This paper summarizes the science rationale and measurement objectives for MASCS, discusses its detailed
design and its calibration requirements, and briefly outlines observation strategies for its use during MESSENGER orbital
operations around Mercury. 相似文献
84.
Paul AL Levine HG McLamb W Norwood KL Reed D Stutte GW Wells HW Ferl RJ 《Acta Astronautica》2005,56(6):623-628
Spaceflight experiments involving biological specimens face unique challenges with regard to the on orbit harvest and preservation of material for later ground-based analyses. Preserving plant material for gene expression analyses requires that the tissue be prepared and stored in a manner that maintains the integrity of RNA. The liquid preservative RNAlater (Ambion) provides an effective alternative to conventional freezing strategies, which are limited or unavailable in current spaceflight experiment scenarios. The spaceflight use of RNAlater is enabled by the Kennedy space center fixation tube (KFT), hardware designed to provide the necessary containment of fixatives during the harvest and stowage of biological samples in space. Pairing RNAlater with the KFT system provides a safe and effective strategy for preserving plant material for subsequent molecular analyses, a strategy that has proven effective in several spaceflight experiments. Possible spaceflight scenarios for the use of RNAlater and KFTs are explored and discussed. 相似文献
85.
Scientists and educators at Baylor College of Medicine are using space life sciences research areas as themes for middle school science and health instructional materials. This paper discusses study findings of the most recent unit, Food and Fitness, which teaches concepts related to energy and nutrition through guided inquiry. Results of a field test involving more than 750 students are reported. Use of the teaching materials resulted in significant knowledge gains by students as measured on a pre/post assessment administered by teachers. In addition, an analysis of the time spent by each teacher on each activity suggested that it is preferable to conduct all of the activities in the unit with students rather than allocating the same total amount of time on just a subset of the activities. 相似文献
86.
William L. Grose 《Advances in Space Research (includes Cospar's Information Bulletin, Space Research Today)》1984,4(4):19-28
The present paper discusses the use of the transformed Eulerian (or “residual”) mean-flow formulation, the Eliassen-Palm flux, and Ertel's potential vorticity to provide an increased understanding of wave, mean-flow interactions, and constituent transport processes in the stratosphere. Temperature and ozone data retrieved from radiance profiles obtained by the LIMS instrument on the Nimbus 7 satellite are utilized in conjunction with these theoretical concepts for the interpretation of phenomena that occurred during the major and minor warmings of January-February 1979. The results illustrate the insight provided by these concepts and demonstrate that useful diagnostic quantities can be derived from global satellite temperature fields. 相似文献
87.
William H. Mish James L. Green Mary G. Reph Mauricio Peredo 《Space Science Reviews》1995,71(1-4):815-877
The International Solar-Terrestrial Physics (ISTP) program will provide simultaneous coordinated scientific measurements from most of the major areas of geospace including specific locations on the Earth's surface. This paper describes the comprehensive ISTP ground science data handling system which has been developed to promote optimal mission planning and efficient data processing, analysis and distribution. The essential components of this ground system are the ISTP Central Data Handling Facility (CDHF), the Information Processing Division's Data Distribution Facility (DDF), the ISTP/Global Geospace Science (GGS) Science Planning and Operations Facility (SPOF) and the NASA Data Archive and Distribution Service (NDADS).The ISTP CDHF is the one place in the program where measurements from this wide variety of geospace and ground-based instrumentation and theoretical studies are brought together. Subsequently, these data will be distributed, along with ancillary data, in a unified fashion to the ISTP Principal Investigator (PI) and Co-Investigator (CoI) teams for analysis on their local systems. The CDHF ingests the telemetry streams, orbit, attitude, and command history from the GEOTAIL, WIND, POLAR, SOHO, and IMP-8 Spacecraft; computes summary data sets, called Key Parameters (KPs), for each scientific instrument; ingests pre-computed KPs from other spacecraft and ground basel investigations; provides a computational platform for parameterized modeling; and provides a number of data services for the ISTP community of investigators. The DDF organizes the KPs, decommutated telemetry, and associated ancillary data into products for duistribution to the ISTP community on CD-ROMs. The SPOF is the component of the GGS program responsible for the development and coordination of ISTP science planning operations. The SPOF operates under the direction of the ISTP Project Scientist and is responsible for the development and coordination of the science plan for ISTP spacecraft. Instrument command requests for the WIND and POLAR investigations are submitted by the PIs to the SPOF where they are checked for science conflicts, forwarded to the GSFC Command Management Syntem/Payload Operations Control Center (CMS/POCC) for engineering conflict validation, and finally incorporated into the conflict-free science operations plan. Conflict resolution is accomplished through iteration between the PIs, SPOF and CMS and in consultation with the Project Scientist when necessary. The long term archival of ISTP KP and level-zero data will be undertaken by NASA's National Space Science Data Center using the NASA Data Archive and Distribution Service (NDADS). This on-line archive facility will provide rapid access to archived KPs and event data and includes security features to restrict access to the data during the time they are proprietary. 相似文献
88.
89.
The nematode Caenorhabditis elegans, a popular organism for biological studies, is being developed as a model system for space biology. The chemically defined liquid medium, C. elegans Maintenance Medium (CeMM), allows axenic cultivation and automation of experiments that are critical for spaceflight research. To validate CeMM for use during spaceflight, we grew animals using CeMM and standard laboratory conditions onboard STS-107, space shuttle Columbia. Tragically, the Columbia was destroyed while reentering the Earth's atmosphere. During the massive recovery effort, hardware that contained our experiment was found. Live animals were observed in four of the five recovered canisters, which had survived on both types of media. These data demonstrate that CeMM is capable of supporting C. elegans during spaceflight. They also demonstrate that animals can survive a relatively unprotected reentry into the Earth's atmosphere, which has implications with regard to the packaging of living material during space flight, planetary protection, and the interplanetary transfer of life. 相似文献
90.
Bains W 《Astrobiology》2004,4(2):137-167
It has been widely suggested that life based around carbon, hydrogen, oxygen, and nitrogen is the only plausible biochemistry, and specifically that terrestrial biochemistry of nucleic acids, proteins, and sugars is likely to be "universal." This is not an inevitable conclusion from our knowledge of chemistry. I argue that it is the nature of the liquid in which life evolves that defines the most appropriate chemistry. Fluids other than water could be abundant on a cosmic scale and could therefore be an environment in which non-terrestrial biochemistry could evolve. The chemical nature of these liquids could lead to quite different biochemistries, a hypothesis discussed in the context of the proposed "ammonochemistry" of the internal oceans of the Galilean satellites and a more speculative "silicon biochemistry" in liquid nitrogen. These different chemistries satisfy the thermodynamic drive for life through different mechanisms, and so will have different chemical signatures than terrestrial biochemistry. 相似文献