Neuritogenesis: a model for space radiation effects on the central nervous system.

Pivotal to the astronauts' functional integrity and survival during long space flights are the strategies to deal with space radiations. The majority of the cellular studies in this area emphasize simple endpoints such as growth related events which, although useful to understand the nature of primary cell injury, have poor predictive value for extrapolation to more complex tissues such as the central nervous system (CNS). In order to assess the radiation damage on neural cell populations, we developed an in vitro model in which neuronal differentiation, neurite extension, and synaptogenesis occur under controlled conditions. The model exploits chick embryo neural explants to study the effects of radiations on neuritogenesis. In addition, neurobiological problems associated with long-term space flights are discussed.     

The observation of the galactic anticenter region by the balloon borne gamma-ray telescope Natalya-I

This paper presents the results of measurements of gamma radiation with energies above 5 MeV, from the galactic anticenter region. The balloon-borne gamma ray telescope “Natalya-I”, was launched on 6 November, 1980 from the Tata Institute of Fundamental Research's Balloon Facility (Hyderabad, India) and reached ceiling altitude of 35 km. The results on the accelerator calibration of the telescope, using a “tagged” gamma ray beam are also presented.     

INMARSAT integrity channels for global navigation satellite systems

The transmission of integrity information using a signal format compatible with the Global Positioning System (GPS) and relayed through a geostationary satellite repeater, which will be critical in achieving high integrity and availability of global navigation by satellite is discussed. The inclusion of navigation repeaters designed to fulfil this function, the next generation of INMARSAT spacecraft, INMARSAT-3 is examined. The global navigation satellite system (GNSS) integrity channel (GIC) will employ pseudorandom codes in the same family as, but distinct from, the codes reserved by GPS. The data format of the basic integrity channel is designed to convey user range error information for 24 to 40 satellites. A closed-loop timing compensation technique will be used at the uplinking Earth station, to make the signal's clock and carrier Doppler variations identical to those that would result from an onboard signal source. Therefore, the INMARSAT-3 satellites will increase the number of useful navigation satellites available to any user, and can also function as sources of precise timing. There is also a possibility that wide area differential corrections can be carried on the same signal     

The instrument IKS and its calibration

The IKS infrared spectro-photometer will fly on board the VEGA platforms. It is designed to characterize the size, temperature and emissivity of the Comet Halley nucleus, to identify the major gaseous components of the inner coma and to detect the emission of the cometary grains. This paper presents the “calibration” experiments required to reduce the raw data: (i) absolute wavelength calibration of the filter wheels; (ii) modeling of the internal signal, as a function of the temperature of the different sub-systems; (iii) absolute and spectral responsivities of each of the spectrometric and photometric channels, as a function of the wavelength and position of the source in the field of view. Finally, we shall indicate the expected S/N ratios.     

What you thought you knew about motion sickness isn't necessarily so

Motion sickness symptoms, stimuli, and drug therapy are discussed. Autogenic feedback training (AFT) methods of preventing motion sickness are explained. Research with AFT indicates that participants who had AFT could withstand longer periods of Coriolis acceleration, participants with high or low susceptibility to motion sickness could control their symptoms with AFT, AFT for Coriolis acceleration is transferable to other motion sickness stimuli, and most people can learn AFT, though with varying rates of learning.     

Systolic time intervals after a seven-day orbital flight.

Heart rate, systolic time intervals (pre-ejection period, left ventricular ejection time , ejection friction, stroke volume and QT interval of two cosmonauts (Leonid Popov--L.P. and Dumitru Prunariu--D.P.) were studied before, during, and after an ergometric bicycle exercise test performed before and after the seven-day Soviet-Romanian orbital flight on the Soyuz 40-Salyut 6 Complex in May 1981. For this purpose one precordial electrocardiogram (ecg) and the ear photodensitopram (den) were recorded stimulaneously. The method used permitted recording even during exercise, Ecg and den signals were stored on magnetic tape, processed in an analogue device and in a digital computer. The data obtained after landing suggest a slight cardiac deconditioning in L.P., demonstrated especially by augmentation of the pre-ejection period, which was unchanged in D.P. corresponding to a sympathoadrenergic hypertonia. The seven-day orbital flight has not produced important cardiovascular changes.     

Initial results from COMPTEL onboard GRO

COMPTEL is the first imaging telescope to explore the MeV gamma-ray range (0.7 to 30 MeV). At present, it is performing a complete sky survey. In later phases of the mission selected celestial objects will be studied in more detail. The data from the first year of the mission have demonstrated that COMPTEL performs very well. First sky maps of the inner part of the Galaxy clearly identify the plane as a bright MeV-source (probably due to discrete sources as well as diffuse radiation). The Crab and Vela pulsar lightcurves have been measured with unprecedented accuracy. The quasars 3C273 and 3C279 have been seen for the first time at MeV energies. Both quasars show a break in their energy spectra in the COMPTEL energy range. The 1.8 MeV line from radioactive ²⁶A1 has been detected from the central region of the Galaxy and a first sky map of the inner part of the Galaxy has been obtained in the light of this line. Upper limits to gamma-ray line emission at 847 keV and 1.238 MeV from SN 1991T have been derived. Upper limits to the interstellar gamma-ray emissivity have been determined at MeV-energies. Several cosmic gamma-ray bursts within the field-of-view have been located with an accuracy of about 1°. On 1991 June 9, 11 and 15, COMPTEL observed gamma-ray emission (continuum and line) from three solar flares. Also neutrons were detected from the June 9 and June 15 flares.     

Pulsar studies with GRO-COMPTEL

Pulsar measurements performed by the experiment COMPTEL, aboard the Compton Gamma Ray Observatory, are described. The main results refer to the Crab and Vela pulsars whose pulse shape characteristics are given in some detail and light curves are compared with those above 50 MeV, as observed by the COS-B satellite. No other gamma-ray pulsars have been detected to date by COMPTEL, the upper limit on the pulsed signal from Geminga being compatible with indications by other experiments.     

Aerosols within the world climate research programme

Based on the findings of the meeting of JSC experts on “Aerosol and Climate” (Geneva, 27–31 October 1980) the general research strategy consisting of three phases will be presented. The three phases are: Phase I: Sensitivity tests with available models Phase II: Improvement of climate models and data bases Phase III: Development of advanced climate models with internal aerosol generation and regulation processes. COSPAR's role within this research strategy is outlined.