Induction of high grade astrocytoma (HGA) by protons: molecular mechanisms and RBE considerations.

Protons of a specific energy, 55 MeV, have been found to induce primary high grade astrocytomas (HGA) in the Rhesus monkey (Macaca mulatta). Brain tumors of this type were not induced by protons of other energies (32-2,300 MeV). Induction of HGA has been identified in human patients who have had radiation therapy to the head. We believe that the induction of HGA in the monkey is a consequence of dose distribution, not some unique "toxic" property of protons. Comparison of the human experience with the monkey data indicates the RBE for induction of brain tumors to be about one. It is unlikely that protons cause an unusual change in oncogenic expression, as compared to conventional electromagnetic radiation.     

Soybean cultivar selection for Bioregenerative Life Support Systems (BLSSs) – Hydroponic cultivation

Four soybean cultivars (‘Atlantic’, ‘Cresir’, ‘Pr91m10’ and ‘Regir’), selected through a theoretical procedure as suitable for cultivation in BLSS, were evaluated in terms of growth and production. Germination percentage and Mean Germination Time (MGT) were measured. Plants were cultivated in a growth chamber equipped with a recirculating hydroponic system (Nutrient Film Technique). Cultivation was performed under controlled environmental conditions (12 h photoperiod, light intensity 350 μmol m⁻² s⁻¹, temperature regime 26/20 °C light/dark, relative humidity 65–75%). Fertigation was performed with a standard Hoagland solution, modified for soybean specific requirements, and EC and pH were kept at 2.0 dS m⁻¹ and 5.5 respectively.     

Height and time variability of planetary wave activity

The height–season and year-to-year regularities of parameters of first and second spatial harmonics determine the structure of the stratosphere and mesosphere circulation and its variability. In the period 1992–2002 at heights 0–55 km, the amplitudes and phases of the first and second spatial harmonics in the field of temperature, geopotential height, zonal and meridional wind were calculated by the method of harmonic decomposition. Dispersion (standard or mean square deviation) of their day-to-day and year-to-year variations was calculated by their wavelength constants. Height and season patterns of variability have been estimated. The difference in height–longitude variability for wave numbers m = 1 and 2 has been discovered. At the same time, the intensity of wave disturbances for m = 1 is less than for m = 2 excluding the polar areas, where a significant variability appears at the heights 0–55 km. There is also a tendency for the intensity of year-to-year variations to decrease in comparison with day-to-day variations. In cold and warm periods the amplitude of perturbation waves with m = 2 both for day-to-day and year-to-year variations is greater than for waves with m = 1. Transient height areas in the interval of 20–30 km are more distinct for day-to-day variations of polar area.     

Relation between galactic and solar cosmic radiation at aviation altitude

Cosmic radiation bombards us at high altitude with ionizing particles; the radiation has a galactic component, which is normally dominant, and a component of solar origin. Cosmic ray particles are the primary source of ionization in the atmosphere above 1 km; below 1 km radon is a dominant source of ionization in many areas.