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681.
Usefulness of daily +2Gz load as a countermeasure against physiological problems during weightlessness. 总被引:2,自引:0,他引:2
Adaptation to head-down-tilt bed rest as a simulated microgravity leads to an abnormality of reflex control of circulation, hypovolemia and reduction of exercise capacity. We hypothesized that this cardiovascular deconditioning and reduction of exercise capacity could be prevented by a daily 1 hr centrifugation at +2Gz. To test this hypothesis, twenty healthy male subjects underwent 4 day of 6 degrees head-down-tilt bed rest. Ten of them were exposed to a +2Gz load for up to 30 min twice per day (the Gz group). The remaining 10 were not exposed to a Gz load (the no-Gz group). We estimated autonomic cardiovascular control by power spectral analysis of blood pressure and R-R interval variability, and baroreflex regulation by the transfer function analysis and the sequence method, before and after bed rest. Further, we measured hematocrit as an index of changes in plasma volume and maximal oxygen consumption as an index of exercise capacity, before and after bed rest. Result: In the no-Gz group, heart rate increased after bed rest. The high frequency power of R-R interval variability as an index of cardiac parasympathetic nervous activity, baroreflex gains estimated by transfer function analysis and the sequence method as index of the integrated arterial-cardiac baroreflex function decreased significantly. Associated with these changes, the ratio of low to high frequency power of R-R as an indicator of cardiac sympathovagal balance tended to increase after bed rest in the no-Gz group. However, those showed no significant changes after bed rest in the Gz group. Hematocrit increased after bed rest in the no-Gz group. It also tended to increase in the Gz group, however it did not achieve statistical significance. Maximal oxygen consumption decreased significantly to similar extent in both the groups. Conclusion: This result suggested that 1) a daily 1hr +2Gz load produced by a centrifuge might eliminate the changes in autonomic cardiovascular control during simulated weightlessness; 2) furthermore, it might partly reverse hypovolemia induced by bed rest; 3) however, it could not prevent the decreases in exercise capacity. 相似文献
682.
M E Vazquez T M Broglio B V Worgul E V Benton 《Advances in Space Research (includes Cospar's Information Bulletin, Space Research Today)》1994,14(10):467-474
Pivotal to the astronauts' functional integrity and survival during long space flights are the strategies to deal with space radiations. The majority of the cellular studies in this area emphasize simple endpoints such as growth related events which, although useful to understand the nature of primary cell injury, have poor predictive value for extrapolation to more complex tissues such as the central nervous system (CNS). In order to assess the radiation damage on neural cell populations, we developed an in vitro model in which neuronal differentiation, neurite extension, and synaptogenesis occur under controlled conditions. The model exploits chick embryo neural explants to study the effects of radiations on neuritogenesis. In addition, neurobiological problems associated with long-term space flights are discussed. 相似文献
683.
R. I. Braslavets 《Cosmic Research》2001,39(1):78-87
Initial preconditions for solving the problem of ballistic-navigation design of a future-technology space navigation system (SNS) are presented. A technical approach to the SNS design is proposed, whose basis is theoretical results in the field of space navigation applied to the orbital satellite groups, generating the global radio navigation field (RNF) with optimum navigation properties. The mathematical apparatus adequate to the proposed technical approach is introduced to analyze the structure of the orbital group and radio navigation field. 相似文献
684.
685.
During strong magnetic storms in July and November of 2004 the fluxes of trapped particles (protons and electrons of MeV energies)
in the Earth’s radiation belts have increased by orders of magnitude and then decreased remaining on an enhanced level for
several months. These enhancements allowed us to study the processes of relaxation of the radiation belts. Measurements of
energetic particles by low-altitude satellites Coronas-F and Servis-1 have shown that predictions of the theory about the rate of pitch-angle diffusion are not always correct, giving both overestimated
and underestimated values for the lifetime of energetic particles. 相似文献
686.
The Siebert and the Dicke-fix CFAR radar detectors, used to maintain a constant false alarm rate (CFAR) in radar receivers under very similar circumstances, are considered. The Siebert detector represents the maximum-likelihood detection procedure for a signal in Gaussian noise of unknown power level, whereas the Dicke-fix makes use of a bandpass limiter to normalize the input and thus ensure a constant false alarm rate. The detection performance of the two detectors is determined and a comparison shows that over a wide range of parameters, the Dicke-fix introduces a loss which is approximately 1 B larger than for the Siebert detector. 相似文献
687.
The observation of the galactic anticenter region by the balloon borne gamma-ray telescope Natalya-I
A.F. Iyudin V.G. Kirillov-Ugryumov Yu.D. Kotov Yu.V. Smirnov L.V. Kurnosova M.I. Fradkin S.V. Damle B.V. Sreekantan G.S. Gokhale P.K. Kunte 《Advances in Space Research (includes Cospar's Information Bulletin, Space Research Today)》1983,3(4):53-56
This paper presents the results of measurements of gamma radiation with energies above 5 MeV, from the galactic anticenter region. The balloon-borne gamma ray telescope “Natalya-I”, was launched on 6 November, 1980 from the Tata Institute of Fundamental Research's Balloon Facility (Hyderabad, India) and reached ceiling altitude of 35 km. The results on the accelerator calibration of the telescope, using a “tagged” gamma ray beam are also presented. 相似文献
688.
E V Benton 《Advances in Space Research (includes Cospar's Information Bulletin, Space Research Today)》1986,6(11):315-328
Measurements of the radiation environment aboard U.S. and Soviet manned spacecraft are reviewed and summarized. Data obtained mostly from passive and some active radiation detectors now exist for the case of low Earth-orbit missions. Major uncertainties still exist for space exposure in high altitude, high inclination, geostationary orbits, in connection with solar effects and that of shielding. Data from active detectors flown in Spacelabs 1 and 2 suggest that a variety of phenomena must be understood before the effects of long-term exposure at the space-station type of orbit and shielding can be properly assessed. 相似文献
689.
J I Gitelson 《Advances in Space Research (includes Cospar's Information Bulletin, Space Research Today)》1992,12(5):167-192
Mars mission like the Lunar base is the first venture to maintain human life beyond earth biosphere. So far, all manned space missions including the longest ones used stocked reserves and can not be considered egress from biosphere. Conventional path proposed by technology for Martian mission LSS is to use physical-chemical approaches proved by the experience of astronautics. But the problem of man living beyond the limits of the earth biosphere can be fundamentally solved by making a closed ecosystem for him. The choice optimum for a Mars mission LSS can be substantiated by comparing the merits and demerits of physical-chemical and biological principles without ruling out possible compromise between them. The work gives comparative analysis of ecological and physical-chemical principles for LSS. Taking into consideration universal significance of ecological problems with artificial LSS as a particular case of their solution, complexity and high cost of large-scale experiments with manned LSS, it would be expedient for these works to have the status of an International Program open to be joined. A program of making artificial biospheres based on preceding experience and analysis of current situation is proposed. 相似文献
690.
The transmission of integrity information using a signal format compatible with the Global Positioning System (GPS) and relayed through a geostationary satellite repeater, which will be critical in achieving high integrity and availability of global navigation by satellite is discussed. The inclusion of navigation repeaters designed to fulfil this function, the next generation of INMARSAT spacecraft, INMARSAT-3 is examined. The global navigation satellite system (GNSS) integrity channel (GIC) will employ pseudorandom codes in the same family as, but distinct from, the codes reserved by GPS. The data format of the basic integrity channel is designed to convey user range error information for 24 to 40 satellites. A closed-loop timing compensation technique will be used at the uplinking Earth station, to make the signal's clock and carrier Doppler variations identical to those that would result from an onboard signal source. Therefore, the INMARSAT-3 satellites will increase the number of useful navigation satellites available to any user, and can also function as sources of precise timing. There is also a possibility that wide area differential corrections can be carried on the same signal 相似文献