Neuritogenesis: a model for space radiation effects on the central nervous system.

Pivotal to the astronauts' functional integrity and survival during long space flights are the strategies to deal with space radiations. The majority of the cellular studies in this area emphasize simple endpoints such as growth related events which, although useful to understand the nature of primary cell injury, have poor predictive value for extrapolation to more complex tissues such as the central nervous system (CNS). In order to assess the radiation damage on neural cell populations, we developed an in vitro model in which neuronal differentiation, neurite extension, and synaptogenesis occur under controlled conditions. The model exploits chick embryo neural explants to study the effects of radiations on neuritogenesis. In addition, neurobiological problems associated with long-term space flights are discussed.     

Effects of test vehicle patterns on cellular coverage measurements

Mobile test systems intended for cellular phone coverage measurements suffer from uncertainties, which are caused by the unpredictable radiation pattern of the measuring antenna installation. Not only do adjacent structures and very common multiple antennas disturb the characteristics, but also in the case of an ideal position does the vertical lobing introduce errors exceeding 10 dB. The problems are likely to be worse in dense urban areas, where multipath from surrounding buildings is the dominating propagation mode     

Local-area helioseismology as a diagnostic tool for solar variability

Dynamical and thermal variations of the internal structure of the Sun can affect the energy flow and result in variations in irradiance at the surface. Studying variations in the interior is crucial for understanding the mechanisms of the irradiance variations. “Global” helioseismology based on analysis of normal mode frequencies, has helped to reveal radial and latitudinal variations of the solar structure and dynamics associated with the solar cycle in the deep interior. A new technique, - “local-area” helioseismology or heliotomography, offers additional potentially important diagnostics by providing three-dimensional maps of the sound speed and flows in the upper convection zone. These diagnostics are based on inversion of travel times of acoustic waves which propagate between different points on the solar surface through the interior. The most significant variations in the thermodynamic structure found by this method are associated with sunspots and complexes of solar activity. The inversion results provide evidence for areas of higher sound speed beneath sunspot regions located at depths of 4–20 Mm, which may be due to accumulated heat or magnetic field concentrations. However, the physics of these structures is not yet understood. Heliotomography also provides information about large-scale stable longitudinal structures in the solar interior, which can be used in irradiance models. This new diagnostic tool for solar variability is currently under development. It will require both a substantial theoretical and modeling effort and high-resolution data to develop new capabilities for understanding mechanisms of solar variability.     

Relaxation of electron and proton radiation belts of the earth after strong magnetic storms

During strong magnetic storms in July and November of 2004 the fluxes of trapped particles (protons and electrons of MeV energies) in the Earth’s radiation belts have increased by orders of magnitude and then decreased remaining on an enhanced level for several months. These enhancements allowed us to study the processes of relaxation of the radiation belts. Measurements of energetic particles by low-altitude satellites Coronas-F and Servis-1 have shown that predictions of the theory about the rate of pitch-angle diffusion are not always correct, giving both overestimated and underestimated values for the lifetime of energetic particles.     

The Detection Performance of the Siebert and Dicke-Fix CFAR Radar Detectors

The Siebert and the Dicke-fix CFAR radar detectors, used to maintain a constant false alarm rate (CFAR) in radar receivers under very similar circumstances, are considered. The Siebert detector represents the maximum-likelihood detection procedure for a signal in Gaussian noise of unknown power level, whereas the Dicke-fix makes use of a bandpass limiter to normalize the input and thus ensure a constant false alarm rate. The detection performance of the two detectors is determined and a comparison shows that over a wide range of parameters, the Dicke-fix introduces a loss which is approximately 1 B larger than for the Siebert detector.     

The observation of the galactic anticenter region by the balloon borne gamma-ray telescope Natalya-I

This paper presents the results of measurements of gamma radiation with energies above 5 MeV, from the galactic anticenter region. The balloon-borne gamma ray telescope “Natalya-I”, was launched on 6 November, 1980 from the Tata Institute of Fundamental Research's Balloon Facility (Hyderabad, India) and reached ceiling altitude of 35 km. The results on the accelerator calibration of the telescope, using a “tagged” gamma ray beam are also presented.     

Summary of radiation dosimetry results on U.S. and Soviet manned spacecraft.

Measurements of the radiation environment aboard U.S. and Soviet manned spacecraft are reviewed and summarized. Data obtained mostly from passive and some active radiation detectors now exist for the case of low Earth-orbit missions. Major uncertainties still exist for space exposure in high altitude, high inclination, geostationary orbits, in connection with solar effects and that of shielding. Data from active detectors flown in Spacelabs 1 and 2 suggest that a variety of phenomena must be understood before the effects of long-term exposure at the space-station type of orbit and shielding can be properly assessed.     

Interaction of growth-determining systems with gravity

The experiments have been carried out with lettuce shoots on board the Salyut-7 orbital station, the Kosmos-1667 biological satellite and under ground conditions at 180° plant inversion. By means of the centrifuge Biogravistat-1M the threshold value of gravitational sensitivity of lettuce shoots has been determined on board the Salyut-7 station. It was found to be equal to 2.9 × 10⁻³g for hypocotyls and 1.5 × 10⁻⁴g for roots. The following results have been received in the experiment performed on board the Kosmos-1667 satellite: a) under microgravity the proliferation of the meristem cells and the growth of roots did not differ from the control; b) the growth of hypocotyls in length was significantly enhanced in microgravity; c) under microgravity transverse growth of hypocotyls (increase in cross sectional area) was significantly increased due to enhancement of cortical parenchyma cell growth. At 180° inversion in Earth's gravity root extension growth and rate of cell division in the root apical meristem were decreased. The determination of DNA-fuchsin value in the nuclei of the cell root apexes showed that inversion affected processess of the cell cycle preceeding cytokinesis.     

INMARSAT integrity channels for global navigation satellite systems

The transmission of integrity information using a signal format compatible with the Global Positioning System (GPS) and relayed through a geostationary satellite repeater, which will be critical in achieving high integrity and availability of global navigation by satellite is discussed. The inclusion of navigation repeaters designed to fulfil this function, the next generation of INMARSAT spacecraft, INMARSAT-3 is examined. The global navigation satellite system (GNSS) integrity channel (GIC) will employ pseudorandom codes in the same family as, but distinct from, the codes reserved by GPS. The data format of the basic integrity channel is designed to convey user range error information for 24 to 40 satellites. A closed-loop timing compensation technique will be used at the uplinking Earth station, to make the signal's clock and carrier Doppler variations identical to those that would result from an onboard signal source. Therefore, the INMARSAT-3 satellites will increase the number of useful navigation satellites available to any user, and can also function as sources of precise timing. There is also a possibility that wide area differential corrections can be carried on the same signal