Critique of some neural network architectures and claims forcontrol and estimation

While there is great potential for successful use of neural network (NN) algorithms in automatic target recognition (ATR) and other pattern identification/classification applications, significant barriers have been encountered that, to date, defy rigorous use of NNs within feedback control designs. The status of several problems and contradictions involving NNs relating to control and estimation theory applications (and to practical failure detection within INS/GPS navigation systems) are summarized here. To give a positive spin and for a balanced perspective, we also mention many novel laudable NN results obtained by invoking the techniques and results of control and estimation theory     

Neoplastic transformation of hamster embryo cells by heavy ions

We have studied the induction of morphological transformation of Syrian hamster embryo cells by low doses of heavy ions with different linear energy transfer (LET), ranging from 13 to 400 keV/μm. Exponentially growing cells were irradiated with ¹²C or ²⁸Si ion beams generated by the Heavy Ion Medical Accelerator in Chiba (HIMAC), inoculated to culture dishes, and transformed colonies were identified when the cells were densely stacked and showed a crisscross pattern. Over the LET range examined, the frequency of transformation induced by the heavy ions increased sharply at very low doses no greater than 5 cGy. The relative biological effectiveness (RBE) of the heavy ions relative to 250 kVp X-rays showed an initial increase with LET, reaching a maximum value of about 7 at 100 keV/μm, and then decreased with the further increase in LET. Thus, we confirmed that high LET heavy ions are significantly more effective than X-rays for the induction of in vitro cell transformation.     

Variations of ionospheric fluctuations of phase delay depending on solar activity: Data of the COSMIC experiment

We present the results of processing and analysis of more than 4500 events of radio occultation sounding of the Earth’s atmosphere observed in the course of the COSMIC experiment on the limb path ‘satellite-ionosphere-satellite’. Events observed in December 2011 (when a number of solar flares occurred) and in January 2012 (when a strong solar proton event took place) were analyzed. It is shown that small-scale variations of electron density increase in polar latitudes, equatorial region, and midlatitudes of the southern hemisphere in January 2012. In the same period, an increase of large-scale variations of electron density is observed during daylight hours in the equatorial region and in the southern hemisphere. No noticeable distinctions in comparison with days of quiet Sun were observed in December 2011.     

Repair of DNA double-strand breaks and cell killing by charged particles.

It has been suggested that it is not simple double-strand breaks (dsb) but the non-reparable breaks which correlate well with the high biological effectiveness of high LET radiations for cell killing (Kelland et al., 1988; Radford, 1986). We have compared the effects of charged particles on cell death in 3 pairs of cell lines which are normal or defective in the repair of DNA dsbs. For the cell lines SL3-147, M10, and SX10 which are deficient in DNA dsb repair, RBE values were close to unity for cell killing induced by charged particles with linear energy transfer (LET) up to 200 keV/micrometer and were even smaller than unity for the LET region greater than 300 keV/micrometer. The inactivation cross section (ICS) increased with LET for all 3 pairs. The ICS of dsb repair deficient mutants was always larger than that of their parents for all the LET ranges, but with increasing LET the difference in ICS between the mutant and its parent became smaller. Since a small difference in ICS remained at LET of about 300 keV/micrometer, dsb repair may still take place at this high LET, even if its role is apparently small. These results suggest that the DNA repair system does not play a major role in protection against the attack of high LET radiations and that a main muse of cell death is non-reparable dsb which are produced at a higher yield compared with low LET radiations. No correlation was observed between DNA content or nuclear area and ICS.     

Empirical modeling of the total electron content in the ionosphere

A method of modeling the total electron content (TEC) based on the semi-empirical ionospheric model developed in Irkutsk State University is suggested. Comparison with the Klobuchar model has shown that the proposed method provides a more accurate presentation of TEC. A conclusion is drawn that the use of this method for compensation of the ionospheric error in single-frequency navigation receivers would lead to a substantial increase in the accuracy of their positioning.     

PowerCore combining structure and batteries for increased energy toweight ratio

Much of the mass of a battery is comprised of nonreactive materials. In an NiH₂ battery, this includes the pressure vessel and 50% of the positive electrode. PowerCore reconfigures the battery materials to serve as a structural sandwich panel. The effective specific energy of the new device can exceed 100 Wh/kg. PowerCore is intended to handle power demands of low Earth orbiting communications satellites such as IRIDIUM. This paper describes the concept and development progress     

Economic methods of improving efficient use of the orbit/spectrum resource by satellite systems

Satellite systems continue to play an important role in the booming market for communication and broadcasting services, driving up demand for use of the orbit/spectrum resource. Studies are required to address the problem of orbit capacity and find ways of making more efficient use of it, to avoid a situation in which there is not enough orbit/spectrum resource to cater for the development of future satellite networks. It is argued that, as far as satellite networks are concerned, the current international regulatory regime governing the use of the spectrum has significant shortcomings, which have a cost, in terms of resources and time, and make investment in satellite projects less attractive. An approach is proposed for improving efficiency of the use of the orbit/spectrum through the introduction of economic methods, to supplement the existing technical and regulatory regime. A spectrum pricing method is proposed for satellite communication systems.     

Clinorotation reduces number, but not size, of cartilaginous nodules formed in micromass cultures of mouse limbbud cells.

In previous studies we used a ground based model to investigate the cellular responses to microgravity by exposing micromass cultures of embryonic limb cells to simulated weightlessness on a clinostat. Cultures set up in T-flasks and rotated at 30 rpm showed that clinostatted cultures had less chondrocyte differentiation than stationary or rotation controls, as assessed by number of nodules/culture stained with cartilage specific Alcian blue. In the current study, nodule size and shape of these nodules was assessed by interactive measurement of area, perimeter, circularity, and equivalent diameters, using the Optimas imaging software. Results show no significant difference in any of the measurements, indicating that clinorotation has no effect on expansion of the nodules either by differentiation of cells within the nodule, or by recruitment of cells into the nodule. The reduction in number of nodules without an alteration in size and shape indicates that the effect of simulated microgravity is to reduce the cell interactions required for the initial condensation of cells into a nodule, probably by interference with cell adhesion molecules.     

New evidence for strong non-thermal effects in Tycho’s supernova remnant

For the case of Tycho’s supernova remnant (SNR), we present the relation between the blast wave and contact discontinuity radii calculated within the nonlinear kinetic theory of cosmic ray (CR) acceleration in SNRs. It is demonstrated that these radii are confirmed by recently published Chandra measurements which show that the observed contact discontinuity radius is very close to the shock radius. Therefore a consistent explanation of these observations can be given in terms of efficient CR acceleration which makes the medium more compressible.     

Postdetection Integration Loss for Logarithmic Detectors

The effect of a logarithmic receiver on the detection performance of a radar has been determined by Green by numerical computations for up to 100 pulses integrated. It was further suggested that the loss in decibels as compared to a square-law detector would appear to be proportional to the logarithm of the number of pulses integrated. In this correspondence we show that this ?conjecture? is false, and that the additional loss when N becomes very large approaches a constant value of 2.2 dB.