质量管理在中国香港的应用(英文)

香港工商企业的质量管理大部分都采用西方的质量管理概念。每当范畴扩展到建立人的优质思想和意识时，便遇到不少困难，基于上述问题，作者进行了一系列的研究，希望了解‘文化’与‘优质管理’之间的关系，并将中国的优良文化传统应用于现代质量管理之中。研究结果显示，‘管理哲学’是重要的一环，而我国的哲学极为丰富，作者借此文章，希望引起更多中国人在这方面的兴趣，从而进行更深入地研究和推广。     

Biodosimetry of heavyions by interphase chromosome painting

We report measurements of chromosomal aberrations in peripheral blood lymphocytes from cancer patients undergoingradiotherapy treatment. Patients with cervix or esophageal cancer were treated with 10 MV X-rays produced at a LINAC accelerator, or high-energy carbon ions produced at the HIMAC accelerator at the National Institute for Radiological Sciences (NIRS) in Chiba. Blood samples were obtained before, during, and after the radiation treatment. Chromosomes were prematurely condensed by incubation in calyculin A. Aberrations in chromosomes 2 and 4 were scored after fluorescence in situ hybridization with whole-chromosome probes. Pre-treatment samples were exposed in vitro to X-rays, individual dose-response curves for the induction of chromosomal aberrations were determined, and used as calibration curves to calculate the effective whole-body dose absorbed during the treatment. This calculated dose, based on the calibration curve relative to the induction of reciprocal exchanges, has a sharp increase after the first few fractions of the treatment, then saturates at high doses. Although carbon ions are 2–3 times more effective than X-rays in tumor sterilization, the effective dose was similar to that of X-ray treatment. However, the frequency of complex-type chromosomal exchanges was much higher for patients treated with carbon ions than X-ray.     

Track segment association, fine-step IMM and initialization with Doppler for improved track performance

In this work we present a new track segment association technique to improve track continuity in large-scale target tracking problems where track breakages are common. A representative airborne early warning (AEW) system scenario, which is a challenging environment due to highly maneuvering targets, close target formations, large measurement errors, long sampling intervals, and low detection probabilities, provides the motivation for the new technique. Previously, a tracker using the interacting multiple model (IMM) estimator combined with an assignment algorithm was shown to be more reliable than a conventional Kalman filter based approach in tracking similar targets but it still yielded track breakages due to the difficult environment. In order to combine the broken track segments and improve track continuity, a new track segment association algorithm using a discrete optimization approach is presented. Simulation results show that track segment association yields significant improvements in mean track life as well as in position, speed, and course rms errors. Also presented is a modified one-point initialization technique with range rate measurements, which are typically ignored by other initialization techniques, and a fine-step IMM estimator, which improves performance in the presence of long revisit intervals. Another aspect that is investigated is the benefit of "deep" (multiframe or N-dimensional, with N > 2) association, which is shown to yield significant benefit in reducing the number of false tracks.     

Genomic instability and tumorigenic induction in immortalized human bronchial epithelial cells by heavy ions

Carcinogenesis is postulated to be a progressive multistage process characterized by an increase in genomic instability and clonal selection with each mutational event endowing a selective growth advantage. Genomic instability as manifested by the amplification of specific gene fragments is common among tumor and transformed cells. In the present study, immortalized human bronchial (BEP2D) cells were irradiated with graded doses of either 1GeV/nucleon ⁵⁶Fe ions or 150 keV/μm alpha particles. Transformed cells developed through a series of successive steps before becoming tumorigenic in nude mice. Tumorigenic cells showed neither ras mutations nor deletion in the p16 tumor suppressor gene. In contrast, they harbored mutations in the p53 gene and over-expressed cyclin D1. Genomic instability among transformed cells at various stage of the carcinogenic process was examined based on frequencies of PALA resistance. Incidence of genomic instability was highest among established tumor cell lines relative to transformed, non-tumorigenic and control cell lines. Treatment of BEP2D cells with a 4 mM dose of the aminothiol WR-1065 significantly reduced their neoplastic transforming response to ⁵⁶Fe particles. This model provides an opportunity to study the cellular and molecular mechanisms involved in malignant transformation of human epithelial cells by heavy ions.     

Observations in the South Atlantic geomagnetic anomaly with intercosmos-Bulgaria-1300 during a geomagnetic storm

The region of South Atlantic Geomagnetic Anomaly (SAGA) was investigated by the Intercosmos-Bulgaria-1300 satellite, launched on August 7, 1981. On the basis of data obtained from 15 orbits during increased geomagnetic activity in August 1981, a map of the Anomaly was elaborated. Two centres of activity were identified. By means of the EMO-5 electrophotometer on board the Intercosmos-Bulgaria-1300 satellite, the atmosphere glow in lines λ 5577 Å, λ 6300 Å and λ 4278 Å was studied.     

Current status and future plans for the general antiparticle spectrometer (GAPS)

We discuss current progress and future plans for the general antiparticle spectrometer experiment (GAPS). GAPS detects antideuterons through the X-rays and pions emitted during the deexcitation of exotic atoms formed when the antideuterons are slowed down and stopped in targets. GAPS provides an exceptionally sensitive means to detect cosmic-ray antideuterons. Cosmic-ray antideuterons can provide indirect evidence for the existence of dark matter in such form as neutralinos or Kaluza–Klein particles. We describe results of accelerator testing of GAPS prototypes, tentative design concepts for a flight GAPS detector, and near-term plans for flying a GAPS prototype on a balloon.     

Studies of vegetation and soils from aerospace measurements

The problem of soil and vegetation recognition with the use of satellite-derived digitized images and sub-satellite spectral brightness measurements at test sites data is discussed. A technique for retrieval of soil humus content is suggested.     

Utility of proposed sensors for coastal engineering studies

The needs of coastal engineering are different from open ocean monitoring or fisheries potential monitoring. A high resolution of 20 meters is essential for identifying several processes that are taking place and influences the coast. A case of application of Landsat MSS to evaluate littoral process highlights the needs for improved spatial resolution. Nevertheless Landsat MSS data for 1981 and 1982 showed that the extent of accretion and erosion that has taken place during this period. Some problems to be addressed for marine remote sensing are mainly regarding the need for insitu data. These aspects are mentioned.     

Implication of multiple dipolarization event near 9 RE for the physics of substorms

In 2001, 2002 and 2003, the Polar spacecraft probed the near equatorial plasma sheet at 9 R_E near local midnight. Using the magnetic field observations, the signatures at substorm onsets are studied. Close to the flux pile-up region, the Polar spacecraft readily detects the dipolarization front, especially for pseudo onsets. An event with two distinct onsets has been examined. The signatures are found to be consistent with the multiple-onset model suggested by Russell [Russell, C.T. How northward turnings of the IMF can lead to substorm expansion onsets. Geophys. Res. Lett. 27, 3257–3259, 2000] which is a modified Near-Earth Neutral Line (NENL) model. Another similar event is also examined showing the effects of different Interplanetary Magnetic Field (IMF) conditions upon substorms. Moreover, ground effects can be very weak compared to in situ observations, especially for pseudo onsets, because these signatures appear to be localized and not global.     

An Automatic Data Processing System for Laser Anemometers

An automatic data processing system for the evaluation of statistically occurring Doppler-difference bursts is described. In addition to the higher accuracy compared with the data acquisition procedures known so far, this technique allows the Doppler-difference method to be used as an operational instrument for investigations into turbulent flows, especially in the case of low particle density and extremely small turbulence degrees.