Evaluation of upper body muscle activity during cardiopulmonary resuscitation performance in simulated microgravity

Performance of efficient single-person cardiopulmonary resuscitation (CPR) is vital to maintain cardiac and cerebral perfusion during the 2–4 min it takes for deployment of advanced life support during a space mission. The aim of the present study was to investigate potential differences in upper body muscle activity during CPR performance at terrestrial gravity (+1Gz) and in simulated microgravity (μG). Muscle activity of the triceps brachii, erector spinae, rectus abdominis and pectoralis major was measured via superficial electromyography in 20 healthy male volunteers. Four sets of 30 external chest compressions (ECCs) were performed on a mannequin. Microgravity was simulated using a body suspension device and harness; the Evetts–Russomano (ER) method was adopted for CPR performance in simulated microgravity. Heart rate and perceived exertion via Borg scores were also measured. While a significantly lower depth of ECCs was observed in simulated microgravity, compared with +1Gz, it was still within the target range of 40–50 mm. There was a 7.7% decrease of the mean (±SEM) ECC depth from 48 ± 0.3 mm at +1Gz, to 44.3 ± 0.5 mm during microgravity simulation (p < 0.001). No significant difference in number or rate of compressions was found between the two conditions. Heart rate displayed a significantly larger increase during CPR in simulated microgravity than at +1Gz, the former presenting a mean (±SEM) of 23.6 ± 2.91 bpm and the latter, 76.6 ± 3.8 bpm (p < 0.001). Borg scores were 70% higher post-microgravity compressions (17 ± 1) than post +1Gz compressions (10 ± 1) (p < 0.001). Intermuscular comparisons showed the triceps brachii to have significantly lower muscle activity than each of the other three tested muscles, in both +1Gz and microgravity. As shown by greater Borg scores and heart rate increases, CPR performance in simulated microgravity is more fatiguing than at +1Gz. Nevertheless, no significant difference in muscle activity between conditions was found, a result that is favourable for astronauts, given the inevitable muscular and cardiovascular deconditioning that occurs during space travel.     

Time-dependent thermal X-ray afterglows from GRBS

Time-dependent thermal X-ray spectra are calculated from physically plausible conditions around GRB. It is shown that account for time-dependent ionization processes strongly affects the observed spectra of hot rarefied plasma. These calculations may provide an alternative explanation to the observed X-ray lines of early GRBs afterglows (such as GRB 011211). Our technique will allow one to obtain independent constraints on the GRB collimation angle and on the clumpiness of circumstellar matter.     

XMM-Newton study of soft excess X-ray emission in clusters of galaxies

We discuss the detection of soft excess X-ray emission in a sample of 19 clusters of galaxies observed by XMM-Newton. In 6/19 clusters evidence for a soft X-ray excess is found. Four of these clusters show soft X-ray and O VII line emission from gas with a temperature of 0.2 keV. The centroid of this oxygen line is consistent with the redshift of the cluster. The intensity and spatial extend of the soft excess agrees with previous PSPC measurements. These observations are interpreted as emission from warm-hot intergalactic medium filaments, with density enhancements near the cluster centers, consistent with theoretical predictions. In the other two soft excess clusters a non-thermal origin is consistent with the data.     

Real time localization of gamma ray bursts with INTEGRAL

The INTEGRAL satellite has been successfully launched in October 2002 and has recently started its operational phase. The INTEGRAL burst alert system (IBAS) will distribute in real time the coordinates of the gamma ray bursts (GRBs) detected with INTEGRAL. After a brief introduction on the INTEGRAL instruments, we describe the main IBAS characteristics and report on the initial results. During the initial performance and verification phase of the INTEGRAL mission, which lasted about two months, two GRBs have been localized with accuracy of 2–4 arcmin. These observations have allowed us to validate the IBAS software, which is now expected to provide quick (few seconds delay) and precise (few arcmin) localization for 10–15 GRBs per year.     

Measuring the matter distribution within z = 0.2 cluster lenses with XMM-Newton

We present an analysis of seven clusters observed by XMM-Newton as part of our survey of 17 most X-ray luminous clusters of galaxies at z  0.2 selected for a comprehensive and unbiased study of the mass distribution in massive clusters. Using the public software FTOOLS and XMMSAS we have set up an automated pipeline to reduce the EPIC MOS and pn spectro-imaging data, optimized for extended sources analysis. We also developped a code to perform intensive spectral and imaging analysis particularly focussing on proper background estimate and removal. XMM-Newton deep spectro-imaging of these clusters allowed us to fit a standard β-model to their gas emission profiles as well as a standard MEKAL emission model to their extracted spectra, and test their inferred characteristics against already calibrated relations.     

The potential of the lichen symbiosis to cope with the extreme conditions of outer space II: germination capacity of lichen ascospores in response to simulated space conditions.

Complementary to the already well-studied microorganisms, lichens, symbiotic organisms of the mycobiont (fungi) and the photobiont (algae), were used as "model systems" in which to examine the ecological potential to resist to extreme environments of outer space. Ascospores (sexual propagules of the mycobiont) of the lichens Fulgensia bracteata, Xanthoria elegans and Xanthoria parietina were exposed to selected space-simulating conditions (up to 16 h of space vacuum at 10(-3) Pa and UV radiation at 160 nm < or = lambda < or = 400 nm), while embedded in the lichen fruiting bodies. After exposure, the ascospores were discharged and their viability was tested as germination capacity on different culture media including those containing Mars regolith simulant. It was found that (i) the germination rate on media containing Mars regolith simulant was as high as on other mineral-containing media, (ii) if enclosed in the ascocarps, the ascospores survived the vacuum exposure, the UV-irradiation as well as the combined treatment of vacuum and UV to a high degree. In general, 50 % or more viable spores were recovered, with ascospores of X. elegans showing the highest survival. It is suggested that ascospores inside the ascocarps are well protected by the anatomical structure, the gelatinous layer and the pigments (parietin and carotene) against the space parameters tested.     

Cellular responses to gravity: extracellular, intracellular and in-between.

Our understanding of gravitational effects (inertial effects in the vicinity of 1 x g) on cells has matured to a stage at which it is possible to define, on the basis of experimental evidence, extracellular effects on small cells and intracellular effects on eukaryotic gravisensing cells. Yet undetermined is the nature of response, if any, of those classes of cells that are not governed solely by extracellular physical events (as are prokaryotes) and are devoid of obvious mechanical devices for sensing inertial forces (such as those possessed by certain plant cells and sensory cells of animals). This "in-between" class of cells needs to be understood on the basis of the combination of intracellular and extracellular gravity-dependent processes that govern experimentally-measurable variables that are relevant to the cell's responses to modified inertial forces. The forces that certain cell types generate or respond to are therefore compared to those imposed by approximately 1 x g in the context of cytoskeletal action and symmetry-breaking pathways.     

Seasonal-to-interannual variability of chlorophyll-a bloom timing associated with physical forcing in the Gulf of Cádiz

Seasonal-to-interannual variability of the winter-spring bloom in the Gulf of Cádiz, eastern North Atlantic, has been investigated using chlorophyll-a remote sensing (CHL). These data have been obtained from the GlobColour project; the temporal coverage extends from September 1997 to December 2010. In this study we develop a generic quantitative approach for describing the temporal variability in the shape of the winter-spring bloom within a region. Variability in both the timing and magnitude of the bloom in the basin has been evaluated as a function of physical properties in the water column such as Mixed Layer Depth (MLD, GODAS model), sea surface temperature (SST, from AVHRR radiometers), photosynthetically-active radiation (PAR, from ocean color data) and euphotic depth (Z_eu, from ocean color data). The analysis indicated that the timing, size and duration of the phytoplankton bloom in this area are largely controlled by both meteorological and oceanographic conditions at different scales; this means that it is likely to vary widely from one year to another.     

Magnetospheric disturbances associated with the 13 December 2006 solar flare and their ionospheric effects over North-East Asia

We present an observational study of magnetospheric and ionospheric disturbances during the December 2006 intense magnetic storm associated with the 4В/Х3.4 class solar flare. To perform the study we utilize the ground data from North–East Asian ionospheric and magnetic observatories (60–72°N, 88–152°E) and in situ measurements from LANL, GOES, Geotail and ACE satellites. The comparative analysis of ionospheric, magnetospheric and heliospheric disturbances shows that the interaction of the magnetosphere with heavily compressed solar wind and interplanetary magnetic field caused the initial phase of the magnetic storm. It was accompanied by the intense sporadic E and F2 layers and the total black-out in the nocturnal subauroral ionosphere. During the storm main phase, LANL-97A, LANL 1994_084, LANL 1989-046 and GOES_11 satellites registered a compression of the dayside magnetosphere up to their orbits. In the morning–noon sector the compression was accompanied by an absence of reflections from ionosphere over subauroral ionospheric station Zhigansk (66.8°N, 123.3°E), and a drastic decrease in the F2 layer critical frequency (foF2) up to 54% of the quite one over subauroral Yakutsk station (62°N, 129.7°E). At the end of the main phase, these stations registered a sharp foF2 increase in the afternoon sector. At Yakutsk the peak foF2 was 1.9 time higher than the undisturbed one. The mentioned ionospheric disturbances occurred simultaneously with changes in the temperature, density and temperature anisotropy of particles at geosynchronous orbit, registered by the LANL-97A satellite nearby the meridian of ionospheric and magnetic measurements. The whole complex of disturbances may be caused by radial displacement of the main magnetospheric domains (magnetopause, cusp/cleft, plasma sheet) with respect to the observation points, caused by changes in the solar wind dynamic pressure, the field of magnetospheric convection, and rotation of the Earth.