Particle trajectories in seeds of Lactuca sativa and chromosome aberrations after exposure to cosmic heavy ions on Cosmos Biosatellites 8 and 9.

The potentially specific importance of the heavy ions of the galactic cosmic radiation for radiation protection in manned spaceflight continues to stimulate in situ, i.e., spaceflight experiments to investigate their radiobiological properties. Chromosome aberrations as an expression of a direct assault on the genome are of particular interest in view of cancerogenesis being the primary radiation risk for man in space. In such investigations the establishment of the geometrical correlation between heavy ions' trajectories and the location of radiation sensitive biological substructures is an essential task. The overall qualitative and quantitative precision achieved for the identification of particle trajectories in the order of approximately 10 micrometers as well as the contributing sources of uncertainties are discussed. We describe how this was achieved for seeds of Lactuca sativa as biological test organisms, whose location and orientation had to be derived from contact photographies displaying their outlines and those of the holder plates only. The incidence of chromosome aberrations in cells exposed during the COSMOS 1887 (Biosatellite 8) and the COSMOS 2044 (Biosatellite 9) mission was determined for seeds hit by cosmic heavy ions. In those seeds the incidence of both single and multiple chromosome aberrations was enhanced. The results of the Biosatellite 9 experiment, however, are confounded by spaceflight effects unrelated to the passage of heavy ions.     

Influence of gravity on the circadian timing system.

The circadian timing system (CTS) is responsible for daily temporal coordination of physiological and behavioral functions both internally and with the external environment. Experiments in altered gravitational environments have revealed changes in circadian rhythms of species ranging from fungi to primates. The altered gravitational environments examined included both the microgravity environment of spaceflight and hyperdynamic environments produced by centrifugation. Acute exposure to altered gravitational environments changed homeostatic parameters such as body temperature. These changes were time of day dependent. Exposure to gravitational alterations of relatively short duration produced changes in both the homeostatic level and the amplitude of circadian rhythms. Chronic exposure to a non-earth level of gravity resulted in changes in the period of the expressed rhythms as well as in the phase relationships between the rhythms and between the rhythms and the external environment. In addition, alterations in gravity appeared to act as a time cue for the CTS. Altered gravity also affected the sensitivity of the pacemaker to other aspects of the environment (i.e., light) and to shifts of time cues. Taken together, these studies lead to the conclusion that the CTS is indeed sensitive to gravity and its alterations. This finding has implications for both basic biology and space medicine.     

A modified Gaussian sum approach to estimation of non-Gaussiansignals

A Gaussian sum estimation algorithm has previously been developed to deal with noise processes that are non-Gaussian. Inherent in this algorithm is a serious growing memory problem that causes the number of terms in the Gaussian sum to increase exponentially at each iteration. A modified Gaussian sum estimation algorithm using an adaptive filter is developed that avoids the growing memory problem of the previous algorithm while providing effective state estimation. The adaptive filter is comprised of a fixed set of estimators operating in parallel with each individual estimate possessing its own corresponding weighting term. A simulation example illustrates the new non-Gaussian estimation technique     

Mutual coupling effects and their reduction in wideband directionof arrival estimation

The performance of multiple signal classification (MUSIC) algorithm using three different inputs over a wideband of frequencies is considered. These inputs are: 1) ideal voltages, 2) actual voltages which include coupling effects and are obtained with the method or moments, and 3) corrected voltages which are obtained from the actual voltages so that the mutual coupling effects are removed. Linear arrays of dipoles, sleeve dipoles, and spiral antennas are considered over 200 MHz to 400 MHz band     

Fusion of sensors with dissimilar measurement/tracking accuracies

The case of data fusion of sensors dissimilar in their measurement/tracking errors is considered. It is shown that the fused track performance is similar whether the sensor data are fused at the track level or at the measurement level. The case of a cluster of targets, resolved by one sensor but not the other, is also considered. Under certain conditions the fused track may perform worse than the worst of the sensors. A remedy to this problem through modifications of the association algorithm is presented     

Reconnection during substorms and solar flares

The patterns of reconnection in the Earth magnetotail and in the solar corona above the active region are presented. The electric field and field-aligned currents (FAC) generation in the current sheet are discussed.     

Turbulence dissipation scale in the inner heliosphere

Small scale turbulence in the solar corona and the solar wind is considered. The estimates of dissipation scale in the inner heliosphere are obtained in the assumption that the initial source of turbulence is located near the chromosphere-corona transition layer. Theoretical results are compared with radiooccultation data.     

Interaction of shocks with a current sheet and reconnection in the solar corona

Interaction of shocks with a current sheet is investigated within a 2D MHD model based on an improved FCT numerical scheme. Basic parameters of the problem are chosen to correspond to situations in the solar corona with low plasma β and moderate shock strength. Slow and fast MHD shocks are introduced with shock normal parallel to magnetic field lines. The interaction with the current sheet causes distortion of the shock front and this distorts the magnetic field lines and generates electric current. Large current densities are generated especially when the fast MHD shock becomes the intermediate MHD shock at the current sheet. Then peak values of the current density are about 3–4 times larger than the initial undisturbed values in the current sheet.     

Infrared spectrometer PFS for the Mars 94 orbiter

Thin films containing a mixture of aliphatic (glycine) and aromatic (tryptophan or tyrosine) amino acids were exposed to a vacuum ultraviolet radiation (VUV) with wavelenghts 100–200 nm. Dipeptides (glycyl-tryptophan and glycyl-tyrosine) were synthesized in these conditions. We compared the actions of VUV and γ-radiation. Polymerization is an essential step in prebiological evolution and we have shown that this stage probably occured over an early Solar system history.     

Heavy-ion induced genetic changes and evolution processes.

On Moon and Mars, there will be more galactic cosmic rays and higher radiation doses than on earth. Our experimental studies showed that heavy ion radiation can effectively cause mutation and chromosome aberrations and that high-LET heavy-ion induced mutants can be irreversible. Chromosome translocations and deletions are common in cells irradiated by heavy particles, and ionizing radiations are effective in causing hyperploidy. The importance of the genetic changes in the evolution of life is an interesting question. Through evolution, there is an increase of DNA content in cells from lower forms of life to higher organisms. The DNA content, however, reached a plateau in vertebrates. By increasing DNA content, there can be an increase of information in the cell. For a given DNA content, the quality of information can be changed by rearranging the DNA. Because radiation can cause hyperploidy, an increase of DNA content in cells, and can induce DNA rearrangement, it is likely that the evolution of life on Mars will be effected by its radiation environment. A simple analysis shows that the radiation level on Mars may cause a mutation frequency comparable to that of the spontaneous mutation rate on Earth. To the extent that mutation plays a role in adaptation, radiation alone on Mars may thus provide sufficient mutation for the evolution of life.