Scan-based emitter passive localization

This paper investigates the problem of estimating the position of a scanning emitter using a passive scan-based geolocation technique. This is achieved by taking advantage of the geometric constraints introduced by the uniform rotating motion of the antenna main beam as it sweeps across a number of separate receivers. A detailed analysis of the estimation process and accuracy of the emitter position is given and a number of computer simulations showing the benefits of this geolocation technique are also included     

Single ion actions: the induction of micronuclei in V79 cells exposed to individual protons.

Understanding the effects of single-particles from conventional radiation biology experiments is problematic due to the stochastics of particle tracks. This complicates the determinations of risk associated with low doses. We have developed a charged particle microbeam, which allows individually counted particles to be delivered to precise cellular locations. The system is capable of delivering a single charged particle with > 99% efficiency. Of these particles 90% are delivered with a resolution of +/- 2 micrometers and 96% with a resolution of +/- 5 micrometers. We have carried out preliminary studies in Chinese hamster V79 cells to monitor the effectiveness of low energy protons at inducing cytological damage. We have used the micronucleus assay as a measure of predominantly lethal chromosome damage. The effects of a single 3.2 MeV proton delivered individually to cells could be measured, with less than 2% of the exposed cells producing micronuclei 24 hours later. The yield of micronuclei formation was essentially linear up to the highest dose (30 particles per cell nucleus) delivered. Ultimately, the ability to target particles to different parts of the cell nucleus may start to impact on models available for chromosome aberration formation and chromosomal Organisation and mechanisms underlying genomic instability.     

Effects of carbon ions on primary cultures of mouse brain cells.

Primary mixed cultures of astrocytes and microglia were obtained from neonatal mice, and were irradiated with high-LET carbon ions. Immunohistochemical staining showed astrocytes survived more prominently than microglia. Tagged with specific antibodies, astrocytes and microglia surviving after irradiation were counted by flow cytometry. Decreases in the number of microglia and astrocytes were detected at a dose as small as 2 Gy when Day 5 cultures were irradiated with 13 keV/micrometer carbon ions. When the cultures were irradiated on Day 10, the dose-dependent decrease of microglia was more prominent for 13 keV/micrometer carbon ions than 70 keV/micrometer carbon ions. Astrocytes showed a marginal decrease at Day 10 and Day 14. We concluded that microglia are more sensitive than astrocytes to carbon ions and X-rays, and that the radiosensitivity of microglia depends on both differentiation/proliferation status and radiation quality.     

Benefits and risks of using electrodynamic tethers to de-orbit spacecraft

By using electrodynamic drag to greatly increase the orbital decay rate, an electrodynamic space tether can remove spent or dysfunctional spacecraft from low Earth orbit (LEO) rapidly and safely. Moreover, the low mass requirements of such tether devices make them highly advantageous compared to conventional rocket-based de-orbit systems. However, a tether system is much more vulnerable to space debris impacts than a typical spacecraft and its design must be proved to be safe up to a certain confidence level before being adopted for potential applications. To assess space debris related concerns, in March 2001 a new task (Action Item 19.1) on the “Potential Benefits and Risks of Using Electrodynamic Tethers for End-of-life De-orbit of LEO Spacecraft” was defined by the Inter-Agency Space Debris Coordination Committee (IADC). Two tests were proposed to compute the fatal impact rate of meteoroids and orbital debris on space tethers in circular orbits, at different altitudes and inclinations, as a function of the tether diameter to assess the survival probability of an electrodynamic tether system during typical de-orbiting missions. IADC members from three agencies, the Italian Space Agency (ASI), the Japan Aerospace Exploration Agency (JAXA) and the US National Aeronautics and Space Administration (NASA), participated in the study and different computational approaches were specifically developed within the framework of the IADC task. This paper summarizes the content of the IADC AI 19.1 Final Report. In particular, it introduces the potential benefits and risks of using tethers in space, it describes the assumptions made in the study plan, it compares and discusses the results obtained by ASI, JAXA and NASA for the two tests proposed. Some general conclusions and recommendations are finally extrapolated from this massive and intensive piece of research.     

Gravisensing in plants and fungi.

The principle of establishing and maintaining a gravitropic set point angle depends on gravisensing and a subsequent cascade of events that result in differential elongation of the responsive structures. Since gravity acts upon masses, the gravisensing mechanisms of all biological systems must follow the same principle, namely the sensing of some force due to differential acceleration of the perceiving entity and a reference structure. This presentation will demonstrate that gravisensing can be accomplished by various means, ranging from cytoskeletal organization, mechano-elastic stress to perturbation of electric signals. However, several arguments indicate that sedimentation of either dense plastids (statoliths), the entire protoplast, or a combination of these represents the primary step in graviperception in plants. In fungi, nuclei and cytoskeletal proteins are believed to form a network capable of gravisensing but sedimenting organelles that may function as statoliths have been identified. Theoretical and practical limitations of gravisensing and detection of acceleration forces necessitate microgravity experiments to identify the primary perceptor, subsequent biochemical mechano-transduction, and biological response processes.     

Influence of long-term hyper-gravity on the reactivity of succinic acid dehydrogenase and NADPH-diaphorase in the central nervous system of fish: a histochemical study.

In the course of a densitometric evaluation, the histochemically demonstrated reactivity of succinic acid dehydrogenase (SDH) and of NADPH-diaphorase (NADPHD) was determined in different brain nuclei of two teleost fish (cichlid fish Oreochromis mossambicus, swordtail fish Xiphophorus helleri), which had been kept under 3g hyper-gravity for 8 days. SDH was chosen since it is a rate limiting enzyme of the Krebs cycle and therefore it is regarded as a marker for metabolic and neuronal activity. NADPHD reactivity reflects the activity of nitric oxide synthase. Nitric oxide (NO) is a gaseous intercellular messenger that has been suggested to play a major role in several different in vivo models of neuronal plasticity including learning. Within particular vestibulum-connected brain centers, significant effects of hyper-gravity were obtained, e.g., in the magnocellular nucleus, a primary vestibular relay ganglion of the brain stem octavolateralis area, in the superior rectus subdivision of the oculomotoric nucleus and within cerebellar eurydendroid cells, which in teleosts possibly resemble the deep cerebellar nucleus of higher vertebrates. Non-vestibulum related nuclei did not respond to hyper-gravity in a significant way. The effect of hyper-gravity found was much less distinct in adult animals as compared to the circumstances seen in larval fish (Anken et al., Adv. Space Res. 17, 1996), possibly due to a development correlated loss of neuronal plasticity.     

Attitude and orbit control systems for the LISA Pathfinder mission

The main purpose of the LISA Pathfinder mission is to provide in-orbit validation of the critical technologies necessary for LISA (Laser Interferometer Space Antenna), aiming at detecting gravitational waves generated by very massive objects such as black holes. The spacecraft consists of a Science Module (SCM) and a Propulsion Module (PRM). The former performs the science experiment, and the later provides the propulsive capability to raise the spacecraft from the injection orbit to the operational orbit at around L1 and is then separated from the former. The Spacecraft Attitude and Orbit Control System (AOCS) is actually composed of three distinct systems to fulfill the needs of the whole mission: – Composite AOCS, used to reach L1, aims at raising the Perigee through a succession of about 10 boosts performed with high thrust chemical propulsion; – Micro-propulsion AOCS takes over once the separation of the SCM from PRM has occurred and is based on micro-propulsion systems (micro-Newton electrical thrusters); – Drag-Free Attitude Control System (DFACS) is then used to perform science experiments. This article provides a comprehensive overview of the AOCS architecture, requirements, selected sensors and actuators, system design & evolution, and achieved performances. It focuses in particular on the Composite AOCS and the Micro-propulsion AOCS and will analyze the challenges of using micro-Newton electric propulsion.     

Cosmic ray hits in the central nervous system at solar maximum.

It has been suggested that a manned mission to Mars be launched at solar maximum rather than at solar minimum to minimize the radiation exposure to galactic cosmic rays. It is true that the number of hits from highly ionizing particles to critical regions in the brain will be less at solar maximum, and it is of interest to estimate how much less. We present here calculations for several sites within the brain from iron ions (z = 26) and from particles with charge, z, greater than or equal to 15. The same shielding configurations and sites in the brain used in an earlier paper for solar minimum are employed so that direct comparison of results between the two solar activity conditions can be made. A simple pressure-vessel wall and an equipment room onboard a spacecraft are chosen as shielding examples. In the equipment room, typical results for the thalamus are that the probability of any particles with 7 greater than or equal to 15 and from 2.3 percent to 1.3 percent for iron ions. The extra shielding provided in the equipment room makes little difference in these numbers. We conclude that this decrease in hit frequency (less than a factor of two) does not provide a compelling reason to avoid solar minimum for a manned mission to Mars. This conclusion could be revised, however, if a very small number of hits is found to cause critical malfunction within the brain.     

Next-Generation Thin-Film Photovoltaics

Future spacecraft and high-altitude airship (HAA) solar array technologies will require high array specific power (W/kg), which can be met using thin-film photovoltaics (PV) on lightweight and flexible substrates [1]. Thin-film array technology, with thin-film specific array support structure, begin to exceed the specific power of crystalline multi-junction arrays with thin-film device efficiencies as low as 8.5% [2]. Thin-film PV devices have other advantages in that they are more easily integrated into HAAs, and are projected to be much less costly than their crystalline PV counterparts. Furthermore, it is likely that only thin-film array technology will be able to meet device specific power requirements exceeding 1 kW/kg (photovoltaic and integrated substrate/blanket mass only).     

Cosmic ray flux at the Earth in a variable heliosphere

In recent years the variability of the cosmic ray flux has become one of the main issues not only for the interpretation of the abundances of cosmogenic isotopes in cosmochronic archives like, e.g., ice cores, but also for its potential impact on the terrestrial climate. It has been re-emphasized that the cosmic ray flux is not only varying due to the solar activity-induced changes of the solar wind but also in response to the changing state of the interstellar medium surrounding the heliosphere. We demonstrate the significance of these external boundary condition changes along the galactic orbit of the Sun for the flux as well as spectra of cosmic rays. Such interstellar–terrestrial relations are a major topic of the International Heliophysical Year 2007.