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261.
Z Han H Suzuki F Suzuki M Suzuki Y Furusawa T Kato Jr. M Ikenaga 《Advances in Space Research (includes Cospar's Information Bulletin, Space Research Today)》1998,22(12):1725-1732
We have studied the induction of morphological transformation of Syrian hamster embryo cells by low doses of heavy ions with different linear energy transfer (LET), ranging from 13 to 400 keV/μm. Exponentially growing cells were irradiated with 12C or 28Si ion beams generated by the Heavy Ion Medical Accelerator in Chiba (HIMAC), inoculated to culture dishes, and transformed colonies were identified when the cells were densely stacked and showed a crisscross pattern. Over the LET range examined, the frequency of transformation induced by the heavy ions increased sharply at very low doses no greater than 5 cGy. The relative biological effectiveness (RBE) of the heavy ions relative to 250 kVp X-rays showed an initial increase with LET, reaching a maximum value of about 7 at 100 keV/μm, and then decreased with the further increase in LET. Thus, we confirmed that high LET heavy ions are significantly more effective than X-rays for the induction of in vitro cell transformation. 相似文献
262.
K Eguchi-Kasai M Murakami H Itsukaichi K Fukutsu F Yatagai T Kanai H Ohara K Sato 《Advances in Space Research (includes Cospar's Information Bulletin, Space Research Today)》1998,22(4):543-549
It has been suggested that it is not simple double-strand breaks (dsb) but the non-reparable breaks which correlate well with the high biological effectiveness of high LET radiations for cell killing (Kelland et al., 1988; Radford, 1986). We have compared the effects of charged particles on cell death in 3 pairs of cell lines which are normal or defective in the repair of DNA dsbs. For the cell lines SL3-147, M10, and SX10 which are deficient in DNA dsb repair, RBE values were close to unity for cell killing induced by charged particles with linear energy transfer (LET) up to 200 keV/micrometer and were even smaller than unity for the LET region greater than 300 keV/micrometer. The inactivation cross section (ICS) increased with LET for all 3 pairs. The ICS of dsb repair deficient mutants was always larger than that of their parents for all the LET ranges, but with increasing LET the difference in ICS between the mutant and its parent became smaller. Since a small difference in ICS remained at LET of about 300 keV/micrometer, dsb repair may still take place at this high LET, even if its role is apparently small. These results suggest that the DNA repair system does not play a major role in protection against the attack of high LET radiations and that a main muse of cell death is non-reparable dsb which are produced at a higher yield compared with low LET radiations. No correlation was observed between DNA content or nuclear area and ICS. 相似文献
263.
Much of the mass of a battery is comprised of nonreactive materials. In an NiH2 battery, this includes the pressure vessel and 50% of the positive electrode. PowerCore reconfigures the battery materials to serve as a structural sandwich panel. The effective specific energy of the new device can exceed 100 Wh/kg. PowerCore is intended to handle power demands of low Earth orbiting communications satellites such as IRIDIUM. This paper describes the concept and development progress 相似文献
264.
Clinorotation reduces number, but not size, of cartilaginous nodules formed in micromass cultures of mouse limbbud cells. 总被引:1,自引:0,他引:1
P J Duke D Montufar-Solis T Hamazaki A Sato 《Advances in Space Research (includes Cospar's Information Bulletin, Space Research Today)》1998,21(8-9):1065-1072
In previous studies we used a ground based model to investigate the cellular responses to microgravity by exposing micromass cultures of embryonic limb cells to simulated weightlessness on a clinostat. Cultures set up in T-flasks and rotated at 30 rpm showed that clinostatted cultures had less chondrocyte differentiation than stationary or rotation controls, as assessed by number of nodules/culture stained with cartilage specific Alcian blue. In the current study, nodule size and shape of these nodules was assessed by interactive measurement of area, perimeter, circularity, and equivalent diameters, using the Optimas imaging software. Results show no significant difference in any of the measurements, indicating that clinorotation has no effect on expansion of the nodules either by differentiation of cells within the nodule, or by recruitment of cells into the nodule. The reduction in number of nodules without an alteration in size and shape indicates that the effect of simulated microgravity is to reduce the cell interactions required for the initial condensation of cells into a nodule, probably by interference with cell adhesion molecules. 相似文献
265.
H.J. Völk E.G. Berezhko L.T. Ksenofontov 《Advances in Space Research (includes Cospar's Information Bulletin, Space Research Today)》2008,41(3):473-476
For the case of Tycho’s supernova remnant (SNR), we present the relation between the blast wave and contact discontinuity radii calculated within the nonlinear kinetic theory of cosmic ray (CR) acceleration in SNRs. It is demonstrated that these radii are confirmed by recently published Chandra measurements which show that the observed contact discontinuity radius is very close to the shock radius. Therefore a consistent explanation of these observations can be given in terms of efficient CR acceleration which makes the medium more compressible. 相似文献
266.
C.-F. Shih T.H. Vonder Haar G.G. Campbell 《Advances in Space Research (includes Cospar's Information Bulletin, Space Research Today)》1985,5(6):197-201
The extraordinary El-Nino event of 1982–83 started to fade out in the late spring of 1983. However the sea surface temperature of the Eastern Equatorial Pacific still remained warmer than normal in the following summer. To investigate the characteristics of this late transition phase of the 1982–83 El-Nino, the GOES-West satellite data of July and August of 1983 are analyzed. The outgoing longwave radiation field and the distribution of cloudiness, which was derived by using a new threshold technique, are obtained. The longwave radiation field is compared to monthly average climatic indices commonly used at the Climatic Analysis Center. The results of cloud analysis showed some interesting features during the decaying phase of the 1982–83 El-Nino. The diurnal variation of cloudiness indicates that total cloud amounts decrease from 8 GMT to 20 GMT over most of the area. This overall study demonstrates preliminary results of the International Satellite Cloud Climatology Project of the World Climate Research Program. 相似文献
267.
N. P. Dmitrieva M. M. Beloshkurskaya T. A. Kornilova I. A. Kornilov 《Cosmic Research》2014,52(4):260-268
The formation of an auroral bulge with a bright dynamical arc at its polar boundary is one of the main manifestations of the magnetospheric substorm expansion phase at the ionospheric level. At the same time, the region of discrete aurora broadens not only polewards but equatorwards as well. The discrete forms of auroras moving equatorwards form a dynamical equatorial boundary of the auroral bulge shifting together with them. The paper presents a spatial-time comparison of the drifting discrete auroras to the injection of energetic particles at the geostationary orbit. It is shown that bursts in the fluxes of energetic particles at the LANL geostationary satellites located in the same sector of MLT correspond to the majority of drifting discrete auroral structures observed by the all-sky camera. In the cases when the bursts in the fluxes are absent, the minimum latitude reached by the auroral structures at the equatorward drift is higher than the ionospheric projection of the geostationary orbit. A possible relation of the drifting discrete auroras to the plasma stream jets in the plasma sheet is discussed. 相似文献
268.
T W Tibbitts S M Bennett R C Morrow R J Bula 《Advances in Space Research (includes Cospar's Information Bulletin, Space Research Today)》1989,9(8):53-59
Potatoes (Solanum tuberosum) have a strong potential as a useful crop species in a functioning CELSS. The cultivar Denali has produced 37.5 g m-2 d-1 when grown for 132 days with the first 40 days under a 12-h photoperiod and a light:dark temperature cycle of 20 degrees C:16 degrees C, and then 92 days under continuous irradiance and a temperature of 16 degrees C. Irradiance was at 725 micromoles m-2 s-1 PPF and carbon dioxide at 1000 micromoles mol-1. The dried tubers had 82% carbohydrates, 9% protein and 0.6% fat. Other studies have shown that carbon dioxide supplementation (1000 micromoles mol-1) is of significant benefit under 12-h irradiance but less benefit under 24 h irradiance. Irradiance cycles of 60 minutes light and 30 minutes dark caused a reduction of more than 50% in tuber weight compared to cycles of 16 h light and 8 h dark. A diurnal temperature change of 22 degrees C for the 12-h light period to 14 degrees C during the 12-h dark period gave increased yields of 30% and 10% for two separate cultivars, compared with plants grown under a constant 18 degrees C temperature. Cultivar screening under continuous irradiance and elevated temperatures (28 degrees C) for 8 weeks of growth indicated that the cvs Haig, Denali, Atlantic, Desiree and Rutt had the best potential for tolerance to these conditions. Harvesting of tubers from plants at weekly intervals, beginning at 8 weeks after planting, did not increase yield over a single final harvest. Spacing of plants on 0.055 centers produced greater yield per m2 than spacing at 0.11 or 0.22 m2. Plants maintained 0.33 meters apart (0.111 m2 per plant) in beds produced the same yields when separated by dividers in the root matrix as when no separation was made. 相似文献
269.
Y Takahashi T Wydeven C Koo 《Advances in Space Research (includes Cospar's Information Bulletin, Space Research Today)》1989,9(8):99-110
Controlled-Ecological-Life-Support-System (CELSS) model wastes were wet-oxidized at temperatures from 250 to 500 degrees C, i.e., below and above the critical point of water (374 degrees C and 218 kg/cm2 or 21.4 MPa). A solution of ammonium hydroxide and acetic acid and a slurry of human urine, feces, and wipes were used as model wastes. Almost all of the organic matter in the model wastes was oxidized in the temperature range from 400 to 500 degrees C, i.e., above the critical conditions for water. In contrast, only a small portion of the organic matter was oxidized at subcritical conditions. Although the extent of nitrogen oxidation to nitrous oxide (N2O) and/or nitrogen gas (N2) increased with reaction temperature, most of the nitrogen was retained in solution as ammonia near 400 degrees C. This important finding suggests that most of the nitrogen in the waste feed can be retained in solution as ammonia during oxidation at low supercritical temperatures and be subsequently used as a nitrogen source for plants in a CELSS while at the same time organic matter is almost completely oxidized to carbon dioxide and water. It was also found in this study the Hastelloy C-276 alloy reactor corroded during waste oxidation. The rate of corrosion was lower above than below the critical temperature for water. 相似文献
270.
N. Kolachevsky A. Matveev J. Alnis C. G. Parthey T. Steinmetz T. Wilken R. Holzwarth T. Udem T. W. Hänsch 《Space Science Reviews》2009,148(1-4):267-288
In this review we discuss the progress of the past decade in testing for a possible temporal variation of the fine structure constant α. Advances in atomic sample preparation, laser spectroscopy and optical frequency measurements led to rapid reduction of measurement uncertainties. Eventually laboratory tests became the most sensitive tool to detect a possible variation of α at the present epoch. We explain the methods and technologies that helped to make this possible. 相似文献