High magnetic gradient environment causes alterations of cytoskeleton and cytoskeleton-associated genes in human osteoblasts cultured in vitro

The effects of a high magnetic gradient environment (HMGE) on the cytoskeletal architecture and genes associated with the cytoskeleton in osteoblasts (MC3T3-E1 and MG-63 cells) were investigated using confocal microscopy, real-time polymerase chain reaction (PCR) and atomic force microscopy (AFM). The findings showed that, under diamagnetic levitation conditions, the architecture and average height of the cytoskeleton and surface roughness in osteoblasts were dramatically altered. HMGE affects cytoskeleton arrangement and cytoskeleton-associated gene expression.     

微小型飞行器的神经网络动态逆控制方法

微小型飞行器(MAV)精确的数学模型很难得到,限制了单纯动态逆控制方法的使用,比例-积分-微分(PID)等传统的控制方法已不能满足要求。针对这一问题,研究了应用动态逆控制方法的新途径──神经网络动态逆。选取串接积分器的多层前向神经网络训练飞行控制系统的动态逆模型,并自适应补偿逆误差。用MATLAB的NNCTRL20工具箱并结合NNSYSID20工具箱建立了仿真系统。升降舵和方向舵联合控制转弯。用PID控制器、近似神经网络动态逆模块、在线神经网络补偿器构建了飞行控制系统。仿真结果表明,神经网络动态逆有较强的鲁棒性、稳定性和指令跟随能力,比PID更适合于微小型飞行器的姿态控制。     

S参数标准的研制和网络分析仪检定

网络分析仪系统是一种宽频段、多参数、并能进行实时测量的大型频域、时域测量系统。主要介绍同轴、波导 S参数标准件的组成、设计方法、研制过程及参数定标的方法。并介绍了双频激光同轴量规计的设计方法、工作原理及利用它对标准件定标的情况。文章中提供了大量的数据 ,详细也列出了标准失配器、标准空气线等 ,S参数标准件在各频率点上定标的数据 ,从各不同方面验证了参数标准的准确性。     

Protostellar Winds and Chondritic Meteorites

We discuss the interaction between the magnetosphere of a young star and its surrounding accretion disk. We consider how an X-wind can be driven magnetocentrifugally from the inner edge of the disk where accreting gas is diverted onto stellar field lines either to flow onto the Sun or to be flung outwards with the wind. The X-wind satisfies many observational tests concerning optical jets, Herbig-Haro objects, and molecular outflows. Connections may exist between primitive solar system materials and X-winds. Chondrules and calcium-aluminum-rich inclusions (CAIs) experienced short melting events uncharacteristic of the asteroid belt where meteorites originate. The inner edge of the solar nebula has the shortest orbital timescale available to the system, a few days. Protosolar flares introduce another timescale, tens of minutes to hours. CAIs may form when solids are lifted from shaded portions of the disk close to the Sun and are exposed to its intense light for a day or so before they are flung by the X-wind to much larger distances. Chondrules were melted, perhaps many times, by flares at larger distances from the Sun before being launched and annealed, but not remelted, in the X-wind. Aerodynamic sorting explains the narrow range of sizes with which CAIs and chondrules are found in chondritic meteorites. Flare-generated cosmic-rays may induce spallation reactions that produce some of the short-lived radioactivities associated with primitive solar system rocks. This revised version was published online in June 2006 with corrections to the Cover Date.     

TCM-2热电偶自动检定系统

ＴＣＭ－２热电偶自动检定系统，采用人机对话的形式，改变了以往检定热电偶的手工操作过程。以微机为中心，配以高精度的控浊信和多通道检测系统，自动控温，进行数据采样与处理，并直接打印检定结果。设有计算和检索的辅助功能。满足国家检定规程的要求。     

Graviresponses of osteocytes under altered gravity

Single cell was capable of sensing and responding to alterations of gravity. Osteocytes, as the most abundant cells of the bone tissue playing an important role in the bone mechanotransduction, are very sensitive to mechanical stimuli. However, the effect of altered gravity on osteocytes so far is less known according to the public papers. Further study on this issue will help to verify and develop the theory of how cells perceive and respond to gravity. It also brings new ideas to the study of space bone loss. In our study, Osteocyte-like MLO-Y4 cells were exposed to 30 parabolic flights three times on ZERO-G airbus A300 to investigate the comprehensive effect on osteocytes stimulated by hyper- and hypo-gravity forces. It showed that the cell morphology, as well as cell area and height, was not changed significantly by hyper-gravity and hypo-gravity. However, the cytoskeleton was reorganized. In flight cells, F-actin polymerization was enhanced at the cell periphery and microtubule organizing center disappeared, but no apoptotic feathers were detected. The results of western blot showed that connexin 43 (Cx43) expression was down-regulated, indicating an decrease of gap-junction. In conclusion, hyper- and hypo-gravity stimulation altered the cytoskeleton architecture and suppressed gap-junction of osteocyte-like MLO-Y4 cells.     

八工位聚氨酯注塑回转自动生产线回转盘系统结构设计

本文介绍了八工位聚氨酯注塑回转自动生产线中回转盘系统的总体设计思路及各部件的结构设计，该系统具有运行平稳，定位准确和制造简单的特点。     

基于GPU加速的binLBT压缩解压算法

地形数据的压缩/解压是大规模地形实时绘制方法的关键步骤,与绘制效率密切相关.通过对压缩/解压方法核心重叠双正交变换的分析,采用重叠双正交变换的整数提升方法将变换中的浮点数操作转换为整数操作及移位操作.使用支持图形处理单元(GPU,Graphic Processing Unit)通用计算的CUDA(Compute Unified Device Architecture)对变换过程及编码过程进行加速.针对数据超出显存容量的情况,采取数据分块的方法将数据分别载入显存进行变换与编码以完成对整体数据的处理.实验结果表明,基于GPU加速的重叠双正交变换整数提升方法的压缩算法有效提高了地形数据处理的效率,并加快了大规模地形绘制速度.     

水击问题的Fourier谱方法计算

给出了推进剂供应系统管路内流体瞬变流动的数学模型,提出了采用Fourier谱方法求解瞬变流非线性偏微分方程的新方法。以一段两端分别连接贮箱和阀的直管道为例,利用该方法对阀门关闭后管道中形成的水击和压力振荡特性进行了求解,给出了相应的仿真结果,与已发表的采用特征线法和有限元法求解结果进行了比较。对数值计算中的非物理振荡问题进行了讨论。     

X-Cor夹层结构的平压性能

通过力学分析得到X-Cor夹层结构平压模量的解析式和计及泡沫对z-pin横向支撑的平压强度预测公式。分析X-Cor夹层结构平压模量的理论值与试验值误差,提出了结构屈曲和z-pin的长度差异引起的刚度折减的修正模型,修正后的夹层结构平压模量的理论值与试验值吻合。理论公式为X-Cor夹层结构的设计提供依据,进而为X-Cor夹层结构新材料在工程领域的应用奠定了基础。