高超声速飞行器动力学规划的落点区域计算

高超声速飞行器的再入过程十分复杂,已知初始状态推断落点区域对飞行器再入航迹规划具有重要意义.本文提出一种基于动力学规划求解高超声速飞行器落点区域的方法.该方法在满足再入轨迹的各种约束条件前提下,在能量-阻力空间里描绘出标称阻力边界曲线,通过反馈线性法对其进行跟踪得到实际可用的上下边界,再经插值计算得到符合约束条件的阻力...     

热激励谐振式硅微结构压力传感器温度场研究

针对一种以方形硅膜片为一次敏感元件、硅梁谐振子为二次敏感元件 ;采用电阻热激励、压敏电阻拾振的压力微传感器 ,分析了其工作机理 ;依幅值、相位条件讨论了该谐振式微传感器的闭环自激系统 ;建立了微传感器的温度场模型和热应力模型 ,并进行了仿真计算与分析     

Inhibitory effect of simulated microgravity on differentiating preosteoblasts

The bone loss induced by microgravity is partly due to the decrease of mature osteoblasts. In the present study, we employed the random positioning machine (RPM) to simulate microgravity and investigated the acute effects of simulated microgravity on the differentiation of 2T3 preosteoblasts. Following 7 days’ culture under normal (1 g) condition, cells were exposed to simulated microgravity for 24 h. The results showed that 24 h treatment of simulated microgravity significantly decreased alkaline phosphatase (ALP) activity without changing the cell morphology. In addition, the mRNA expressions of osteogenic genes, including runt-related gene 2 (Runx2), osterix, osteocalcin (OC), type I collagen (Col I) and bone morphogenetic protein (BMP), were dramatically downregulated. Moreover, western blot analysis of total extracellular signal-regulated kinase (Erk) and phosphorylated Erk (p-Erk) indicated that p-Erk level, which represents the Erk activation status, was increased. Taken together, our results suggested that acute exposure to simulated microgravity inhibited osteoblast differentiation through modulating the expression of osteogenic genes and the Erk activity. These findings provide new insight for bone loss due to microgravity and unloading.     

Calcium influx through stretch-activated channels mediates microfilament reorganization in osteoblasts under simulated weightlessness

We have explored the role of Ca²⁺ signaling in microfilament reorganization of osteoblasts induced by simulated weightlessness using a random positioning machine (RPM). The RPM-induced alterations of cell morphology, microfilament distribution, cell proliferation, cell migration, cytosol free calcium concentration ([Ca²⁺]_i), and protein expression in MG63 osteoblasts were investigated. Simulated weightlessness reduced cell size, disrupted microfilament, inhibited cellular proliferation and migration, and induced an increase in [Ca²⁺]_i in MG63 human osteosarcoma cells. Gadolinium chloride (Gd), an inhibitor for stretch-activated channels, attenuated the increase in [Ca²⁺]_i and microfilament disruption. Further, the expression of calmodulin was significantly increased by simulated weightlessness, and an inhibitor of calmodulin, W-7, aggravated microfilament disruption. Our findings demonstrate that simulated weightlessness induces Ca²⁺ influx through stretch-activated channels, then results in microfilament disruption.     

模糊判别在软件可靠性加速测试中的应用

从软件可靠性测试的基本特点出发,分析软件可靠性测试用例之间存在的相似性;并利用模糊数学中的一系列原理,对软件可靠性测试用例特征进行处理;对测试用例相似性进行组合模糊判别,若相似性达到一定置信度,则对该测试用例进行不执行而累积测试时间的处理过程,从而加速软件可靠性测试.该方法只对软件可靠性测试用例特征进行分析处理,对软件可靠性评估模型没有影响,因此一定程度上减小了评估误差,同时在软件可靠性加速测试方面进行了新的尝试.     

基于模拟退火算法的可靠性优化

建立了可靠性冗余优化模型，分析了各种优化方法的优缺点，采用模拟退火算法解决了此总是要，通过实例给出了算法，并与启发式算法作了比较，结果表明该方法比较有效。     

地球同步卫星轨道交会时的状态估计与参数估计

本文将一种有效的自适应滤波方案成功地应用于地球同步卫星轨道交会时的状态估计与参数估计之中。模拟计算的数值结果表明,状态估值与参数估值都能够达到满意的精度。     

克服柱塞式加力燃油泵汽蚀的措施

根据对柱塞式加力燃油泵汽蚀产生机理的认识，重新设计了分油盘的过渡区，试验证明：它对抑制汽蚀的产生效果显著，能削弱柱塞上的冲击负荷，从而可提高油泵的可靠性和寿命。     

双转子涡喷发动机的转差调整

本文分析了双转子涡喷发动机转差的概念和作用,指出转差的大小将影响高低压压气机的稳定工作裕度和高压转子的转速n_2与涡轮前燃气温度T_3的匹配问题。本文提出如何正确调整转差,其结果与实际台架试车数据基本符合。此外,还提供转差对推力、单位燃油消耗率、n_2和T_3的影响关系,可供实际应用参考。     

固体发动机药柱热线粘弹性边界元分析

采用遗传积分形式的本构关系,推导了热线粘弹性材料时域边界元公式。由于把与时间有关的剪切模量G(t)表示成Pnony级数的形式,因而可用递推公式较方便地计算粘弹性记忆应力。本文提出的方法比以前的对应原理方法有较广的应用范围。为了验证提出的方法,编制了二维粘弹性边界元程序。两个算例的数值结果表明:本方法具有精度高,计算机解题快,占内存少等优点。