Photochemical synthesis of citric acid cycle intermediates based on titanium dioxide

The emergence of the citric acid cycle is one of the most remarkable occurrences with regard to understanding the origin and evolution of metabolic pathways. Although the chemical steps of the cycle are preserved intact throughout nature, diverse organisms make wide use of its chemistry, and in some cases organisms use only a selected portion of the cycle. However, the origins of this cycle would have arisen in the more primitive anaerobic organism or even back in the proto-metabolism, which likely arose spontaneously under favorable prebiotic chemical conditions. In this context, we report that UV irradiation of formamide in the presence of titanium dioxide afforded 6 of the 11 carboxylic acid intermediates of the reductive version of the citric acid cycle. Since this cycle is the central metabolic pathway of contemporary biology, this report highlights the role of photochemical processes in the origin of the metabolic apparatus.     

The O/OREOS mission: first science data from the Space Environment Survivability of Living Organisms (SESLO) payload

We report the first telemetered spaceflight science results from the orbiting Space Environment Survivability of Living Organisms (SESLO) experiment, executed by one of the two 10?cm cube-format payloads aboard the 5.5?kg Organism/Organic Exposure to Orbital Stresses (O/OREOS) free-flying nanosatellite. The O/OREOS spacecraft was launched successfully to a 72° inclination, 650?km Earth orbit on 19 November 2010. This satellite provides access to the radiation environment of space in relatively weak regions of Earth's protective magnetosphere as it passes close to the north and south magnetic poles; the total dose rate is about 15 times that in the orbit of the International Space Station. The SESLO experiment measures the long-term survival, germination, and growth responses, including metabolic activity, of Bacillus subtilis spores exposed to the microgravity, ionizing radiation, and heavy-ion bombardment of its high-inclination orbit. Six microwells containing wild-type (168) and six more containing radiation-sensitive mutant (WN1087) strains of dried B. subtilis spores were rehydrated with nutrient medium after 14 days in space to allow the spores to germinate and grow. Similarly, the same distribution of organisms in a different set of microwells was rehydrated with nutrient medium after 97 days in space. The nutrient medium included the redox dye Alamar blue, which changes color in response to cellular metabolic activity. Three-color transmitted intensity measurements of all microwells were telemetered to Earth within days of each of the 48?h growth experiments. We report here on the evaluation and interpretation of these spaceflight data in comparison to delayed-synchronous laboratory ground control experiments.     

积极主动的发动机维修

运营商越来越多地发现发动机预防性维修的长期价值. 要使航空公司能够对发动机维修变得更为积极主动,说起来容易做起来难,即使航空运输回暖和航空公司收入增加的情况下也是这样.     

Interplanetary Origin of Intense,Superintense and Extreme Geomagnetic Storms

We present a review on the interplanetary causes of intense geomagnetic storms (Dst≤−100 nT), that occurred during solar cycle 23 (1997–2005). It was reported that the most common interplanetary structures leading to the development of intense storms were: magnetic clouds, sheath fields, sheath fields followed by a magnetic cloud and corotating interaction regions at the leading fronts of high speed streams. However, the relative importance of each of those driving structures has been shown to vary with the solar cycle phase. Superintense storms (Dst≤−250 nT) have been also studied in more detail for solar cycle 23, confirming initial studies done about their main interplanetary causes. The storms are associated with magnetic clouds and sheath fields following interplanetary shocks, although they frequently involve consecutive and complex ICME structures. Concerning extreme storms (Dst≤−400 nT), due to the poor statistics of their occurrence during the space era, only some indications about their main interplanetary causes are known. For the most extreme events, we review the Carrington event and also discuss the distribution of historical and space era extreme events in the context of the sunspot and Gleissberg solar activity cycles, highlighting a discussion about the eventual occurrence of more Carrington-type storms.     

The Effect of Hard Limiting in the Presence of Large Out-of-Band Interfering Signals

The effect of hard limiting on the phase of a test signal was investigated when large out-of-band interfering signals are present at the input to the limiter. First a single and then two discrete interfering signals were considered. The interfering signals and the test signal are restricted to narrow but separated bands. The test signal is recovered after limiting by narrowband filtering. The analysis of the single interfering signal is essentially the same as that performed by Cahn.1 In this correspondence experimental evidence is presented to verify the analysis and, in addition, the case of two interfering signals is considered.     

Ocean Engineering in the U. S. Navy

This paper is the complete text of an address given at the IEEE meeting in New York on March 23, 1966, in ?Undersea Technology Session,? covering the U. S. Navy's furtherance of the development of Ocean Engineering and some plans for the future. The items covered include the deep submergence systems project, SEALAB III, salvage work packages circa 1967, and additions to the Marine Engineering Laboratory.     

The new millennium program: Fast-track procurements

The National Aeronautics and Space Administration's (NASA's) New Millennium Program (NMP) has embarked on a technology flight-validation demonstration program to enable the kinds of missions that NASA envisions for the 21st century. Embedded in this program is the concept of rapid mission development supported by a fast-track procurement process. This process begins with the decision to initiate a procurement very early in the program along with the formation of a technical acquisition team. A close working relationship among the team members is essential to avoiding delays and developing a clear acquisition plan. The request for proposal (RFP) that is subsequently issued seeks a company with proven capabilities, so that the time allotted for responses from proposers and the length of proposals they submit can be shortened. The fast-track procurement process has been demonstrated during selection of NMP's industrial partners and has been proven to work.     

Infrared irradiance calibration

Infrared astronomical measurements are calibrated against reference sources, usually primary standard stars that are, in turn, calibrated either by direct or indirect means. A direct calibration compares the star with a certified source, typically a blackbody. Indirect methods extrapolate a direct measurement of the flux at one wavelength to the flux at another. Historically, α Lyr (Vega) has been used as the primary standard as it is bright, easily accessible from the northern hemisphere, and is well calibrated in the visual. Until recently, the direct absolute infrared calibrations of α Lyr and those derived from the absolute solar flux scaled to the observed spectral energy distributions of solar type stars increasingly diverged with wavelength from those obtained using a model atmosphere to extrapolate the absolute visual flux of Vega into the infrared. The exception is the direct calibration by the 1996/97 Midcourse Space Experiment of the absolute fluxes for a number of the commonly used infrared standard stars, including Vega.In the mid-1980s, the Air Force Geophysics Laboratory began a program that led to the establishment of a network of stars with which to calibrate infrared space-based sensors. α Lyr and a CMa were adopted as the fundamental references and the absolute 1.2 to 35 µm infrared spectral energy distributions for the 616 secondary standard stars in the network were derived through spectral and photometric comparisons with the primary standards. The stars are also used for calibration at ground-based infrared observatories. For applications in which the network stars may not be bright enough, particularly at the longer infrared wavelengths, planets and the larger asteroids are used. Planets and asteroids move and rather sophisticated thermal modeling of the bodies is required to predict the disk-integrated brightness at a specific time with reasonable accuracy. The Infrared Space Observatory applied such a sophisticated ‘thermo-physical’ model to the largest asteroids to support calibration of the sensors to a claimed accuracy of within 5%. The AFRL program also created a spectral atlas of the brightest stars in the sky that, although they are variable, may be used for calibration if the large(r) attendant uncertainties are acceptable.This revised version was published online in July 2005 with a corrected cover date.     

Global Non-Potential Magnetic Models of the Solar Corona During the March 2015 Eclipse

Seven different models are applied to the same problem of simulating the Sun’s coronal magnetic field during the solar eclipse on 2015 March 20. All of the models are non-potential, allowing for free magnetic energy, but the associated electric currents are developed in significantly different ways. This is not a direct comparison of the coronal modelling techniques, in that the different models also use different photospheric boundary conditions, reflecting the range of approaches currently used in the community. Despite the significant differences, the results show broad agreement in the overall magnetic topology. Among those models with significant volume currents in much of the corona, there is general agreement that the ratio of total to potential magnetic energy should be approximately 1.4. However, there are significant differences in the electric current distributions; while static extrapolations are best able to reproduce active regions, they are unable to recover sheared magnetic fields in filament channels using currently available vector magnetogram data. By contrast, time-evolving simulations can recover the filament channel fields at the expense of not matching the observed vector magnetic fields within active regions. We suggest that, at present, the best approach may be a hybrid model using static extrapolations but with additional energization informed by simplified evolution models. This is demonstrated by one of the models.