Emesis and space motion sickness in amphibians.

Amphibians possess the ability to vomit in response to a variety of stimuli that provoke emesis in mammals. Pharmacological studies have establish that the ejection of gastric contents and the basic mechanism for vomiting have been phylogenetically conserved among these tetrapods. As part of on-going comparative studies on emesis in vertebrates, we previously documented that some postmetamorphic anurans and salamander larvae experience motion-induced emesis when exposed to the provocative stimulus of parabolic aircraft flight. However, more recent experiments suggest that there are strict conditions for inducing emesis in amphibians exposed to parabolic flight and that amphibians are not as sensitive to this stimulus as mammals. Further studies on emesis in lower vertebrates may help us understand the processes that cause emesis in abnormal gravitational regimes.     

Integration test project of CEEF--a test bed for Closed Ecological Life Support Systems.

CEEF (Closed Ecology Experiment Facilities) were installed at Rokkasho village in northern Japan, for the purpose of clarifying life-support mechanisms in a completely closed space, such as a Lunar or Mars base. An integration test using the Closed Plantation Experiment Facility and Closed Animal Breeding & Habitation Experiment Facility is needed before conducting an entire closed experiment including plants, animals and humans. These integration tests are planned to be conducted step by step from fiscal 2001 to 2008.     

Determination of parameters of rotational motion of the <Emphasis Type="Italic">Monitor-E</Emphasis> spacecraft from the telemetry data on solar batteries’ current

The Monitor-E spacecraft executed uncontrolled flight due to emergency situation, no telemetry information on parameters of the spacecraft’s attitude motion being available. So, the problem arose to determine the spacecraft’s rotational motion from the accessible indirect information—the electric current provided by solar batteries. In this paper the integrated statistical technique is described, that allows one to solve this problem. The values of current, obtained over the time interval some tens of minutes long, have been processed simultaneously by the least squares method using the integration of the equations of spacecraft’s rotational motion. As a result of processing, the initial conditions of motion were estimated, and the spacecraft’s moments of inertia were updated, as well as the angles, specifying solar batteries position in the spacecraft-fixed coordinate system. The results of processing of 12 data sets are presented, which allowed us to reconstruct the actual rotational motion of the spacecraft.     

The human cardiovascular system during space flight

Purpose of the work is to analyze and to summarize the data of investigations into human hemodynamics performed over 20 years aboard orbital stations Salyut-7 and Mir with participation of 26 cosmonauts on space flights (SF) from 8 to 438 days in duration. The ultrasonic techniques and occlusive plethysmography demonstrated dynamics of changes in the cardiovascular system during SF of various durations. The parameters of general hemodynamics, the pumping function of the heart and arterial circulation in the brain remained stable in all the space flights; however, there were alterations in peripheral circulation associated with blood redistribution and hypovolemie in microgravity. The anti-gravity distribution of the vascular tone decayed gradually as unneeded. The most considerable changes were observed in leg vessels, equally in arteries (decrease in resistance) and veins (increase in maximum capacity). The lower body negative pressure test (LBNP) revealed deterioration of the gravity-dependent reactions that changed for the worse as SF duration extended. The cardiovascular deconditioning showed itself as loss of descent acceleration tolerance and orthostatic instability in the postflight period.     

Moderate geomagnetic storms and their ionospheric effects at middle and low latitudes

This paper reports the global response of the mid high and low latitude ionosphere in four longitudinal sectors to two moderate geomagnetic storms that occurred during 2007 (the more intense storms occurred that year). The results obtained during these storms show that the ionospheric effects in general are not moderate in magnitude, showing an important degree of complexity as during intense storms. The outstanding features produced during the storms are significant positive storm effects at mid-high latitudes during the main phase/first part of the recovery, positive effects after the onset of the storm followed by negatives effects at middle latitudes and delayed positive effects during the night-time hours in the trough of the equatorial anomaly (“dusk” effect). Possible physical mechanisms for controlling the morphology of the ionosphere during these events are considered.     

Harnessing functional food strategies for the health challenges of space travel—Fermented soy for astronaut nutrition

Astronauts face numerous health challenges during long-duration space missions, including diminished immunity, bone loss and increased risk of radiation-induced carcinogenesis. Changes in the intestinal flora of astronauts may contribute to these problems. Soy-based fermented food products could provide a nutritional strategy to help alleviate these challenges by incorporating beneficial lactic acid bacteria, while reaping the benefits of soy isoflavones. We carried out strain selection for the development of soy ferments, selecting strains of lactic acid bacteria showing the most effective growth and fermentation ability in soy milk (Streptococcus thermophilus ST5, Bifidobacterium longum R0175 and Lactobacillus helveticus R0052). Immunomodulatory bioactivity of selected ferments was assessed using an in vitro challenge system with human intestinal epithelial and macrophage cell lines, and selected ferments show the ability to down-regulate production of the pro-inflammatory cytokine interleukin-8 following challenge with tumour necrosis factor-alpha. The impact of fermentation on vitamin B1 and B6 levels and on isoflavone biotransformation to agluconic forms was also assessed, with strain variation-dependent biotransformation ability detected. Overall this suggests that probiotic bacteria can be successfully utilized to develop soy-based fermented products targeted against health problems associated with long-term space travel.     

Identification of Aircraft Stability and Control Parameters Using Hierarchical State Estimation

Previous attempts to identify aircraft stability and control derivatives from flight test data, using three-degrees-of-freedom (3-DOF) longitudinal or lateral-directional perturbation equation-of-motion models, suffer from the disadvantage that the coupling between the longitudinal and lateral-directional dynamics has been ignored. In this paper, the identification of aircraft stability parameters is accomplished using a more accurate 6-DOF model which includes this coupling. Hierarchical system identification theory is used to reduce the computational effort involved. The 6-DOF system of equations is first decomposed into two 3-DOF subsystems, one for the longitudinal dynamics and the other for the lateral-directional dynamics. The two subsystem parameter identification processes are then coordinated in such a way that the overall system parameter identification problem is solved. Next, a six-subsystem decomposition is considered. Computational considerations and comparison with the unhierarchically structured problem are presented.