Space experiments aboard the Lomonosov MSU satellite

At present, the Institute of Nuclear Physics of Moscow State University, in cooperation with other organizations, is preparing space experiments onboard the Lomonosov satellite. The main goal of this mission is to study extreme astrophysical phenomena such as cosmic gamma-ray bursts and ultra-high-energy cosmic rays. These phenomena are associated with the processes occurring in the early universe in very distant astrophysical objects, therefore, they can provide information on the first stages of the evolution of the universe. This paper considers the main characteristics of the scientific equipment aboard the Lomonosov satellite.     

Frequency fluctuations of coherent signals from spacecraft observed during dual-frequency radio sounding of the circumsolar plasma in 2004–2008

We have performed spectral processing of the data of experiments on radio sounding of circumsolar plasma by coherent S- and X-band signals from the spacecraft Ulysses, Mars Express, Rosetta, and Venus Express carried out from 1991 to 2009. The experiments were realized in the mode of coherent response, when a signal stabilized by the hydrogen standard is transmitted from the ground station to a spacecraft, received by the onboard systems, and retransmitted to the Earth with conserved coherence. Thus, the signal sounding the coronal plasma passes twice through the medium: on the propagation path ground station — spacecraft and on the same path in the opposite direction. The spectra of frequency fluctuations in both the bands are obtained and, using them, the radial dependences of fluctuation intensities are found, which can be approximated by a power law. It is shown that the ratio of intensities of frequency fluctuations in the S- and X-bands is comparable with the theoretical value and characterizes the degree of correlation of irregularities of the electron density along the propagation path ground station — spacecraft and back. Analysis of the correlation of frequency fluctuations on the two paths allows one to get a lower estimate of the outer scale of the circumsolar plasma turbulence. For heliocentric distances R = 10 solar radii (R _S ) the outer scale is larger than 0.25R _S .     

Advanced materials for next generation NiMH portable, HEV and EVbatteries

While Ovonic NiMH batteries are already in high volume commercial production for portable applications, advances in materials technology have enabled performance improvements in specific energy (100 Wh/kg), specific power (600-1000 W/kg), high temperature operation, charge retention, and voltage stability. Concurrent with technology advances, Ovonic NiMH batteries have established performance and commercial milestones in electric vehicles, hybrid electric vehicles, as well as scooter, motorcycle and bicycle applications. As important as these advances, significant manufacturing cost reductions have also occurred which allow continued growth of NiMH technology. In this paper, advances in performance, applications and cost reduction are discussed with particular emphasis on the improved proprietary metal hydride and nickel hydroxide materials that make such advances possible     

Influence of microgravity on mitogen binding and cytoskeleton in Jurkat cells.

The effects of microgravity on Jurkat cells--a T-lymphoid cell line--was studied on a sounding rocket flight. An automated pre-programmed instrument permitted the injection of fluorescent labelled concanavalin A (Con A), culture medium and/or fixative at given times. An in-flight 1 g centrifuge allowed the comparison of the data obtained in microgravity with a 1 g control having the same history related to launch and re-entry. After flight, the cells fixed either at the onset of microgravity or after a or 12 minute incubation time with fluorescent concanavalin A were labelled for vimentin and actin and analysed by fluorescence microscopy. Binding of Con A to Jurkat cells is not influenced by microgravity, whereas patching of the Con A receptors is significantly lower. A significant higher number of cells show changes in the structure of vimentin in microgravity. Most evident is the appearance of large bundles, significantly increased in the microgravity samples. No changes are found in the structure of actin and in the colocalisation of actin on the inner side of the cell membrane with the Con A receptors after binding of the mitogen.     

Reducing Undesirable Effects in the Human Centrifuge

The human centrifuge is used to train pilots and astronauts for flights where they are subject to large accelerations. This paper deals with the problems of simulating such linear accelerations with a rotating device and presents suitable means of reducing undesirable simulation error. The advantages of using three gimbals rather than the usual two are considered. Numerical results illustrate the problems of simulation and the improvement achieved by the use of a third gimbal.     

Signal transduction in T lymphocytes--a comparison of the data from space, the free fall machine and the random positioning machine.

In this paper we discuss the effect of microgravity on T cells and we present the data of studies with two new machines for 0 g simulations. Several experiments in space show that mitogenic T cell activation is lost at 0 g. Immunocytochemistry indicates that such effect is associated with changes of the cytoskeleton. Biochemical studies suggest that the lack of expression of the interleukin-2 receptor is one of the major causes of the loss of activity. In fact, interleukin-2 is the third signal required for full activation. In order to deepen our investigations we are now working with the free-fall machine, FFM, invented by D. Mesland, and with the random positioning machine, RPM, or three-dimensional clinostat, developed by T. Hoson. The FFM produces periods of free-fall lasting approximately 800 ms followed by bounces of 15-30 g lasting 45-60 ms. The RPM eliminates the effect of gravity by rotating biological specimen randomly around two orthogonal axes. While the FFM failed to reproduce the results obtained with T lymphocytes in space, the data from the RPM are in good agreement with those in real microgravity. In fact, the inhibition of the mitotic index in the RPM is 89% compared to static controls. The RPM (as the FFM) can carry markedly larger specimen than the fast rotating clinostat and thus allows to conduct comprehensive studies to select suitable biological objects for further investigations in space.     

Protein crystal growth--microgravity aspects.

Protein crystals, grown under reduced gravity conditions, are either superior or inferior in their structural perfection than their Earth-grown counterparts. A reduction of the crystals' quality due to low-gravity effects on the growth processes cannot be understood from existing models. In this paper we put forth a rationale which predicts either advantages or disadvantages of microgravity growth. This rationale is based on the changes in the effective solute and impurity supply rates in microgravity and their effects on the intrinsic growth rate fluctuations that arise from the coupling of bulk transport to nonlinear interfacial kinetics and cause severe inhomogeneities. Depending on the specific diffusivity and kinetic coefficient of a protein and the impurities in the solution, either transport enhancement through forced flow or transport suppression under reduced gravity can result in a reduction of the kinetic fluctuations and, thus, growth with higher structural perfection. Investigating this mechanism of microgravity effects, we first demonstrate a one-to-one correspondence between these fluctuations, that are due to the bunching of growth steps, and the formation of defects in the crystals. We have confirmed the forced flow aspects of this rationale in ground-based experiments with lysozyme utilizing flowing solutions with varying, well characterized impurity contents.     

Categorical Bias in Line Angle Judgments: Sex Differences and the Use of Multiple Categories

According to the Category Adjustment (CA) model, spatial estimates (e.g., of location) involve Bayesian combination across multiple, hierarchical pieces information, each weighted by its relative certainty. Recent work, though, has shown that men and women differ in terms of their certainty regarding fine-grained and categorical information in location memory. Here we demonstrate that this reflects a more general sex difference in visuospatial processing by examining bias patterns in a line angle judgment task (JLAP-15). In addition, the data suggest that multiple, hierarchical levels of categorical information influenced spatial judgments. These results imply that the hierarchical combination outlined by the CA model extends beyond two levels, and that men and women apply differential weighting to these representations.     

Synergies between plant research conducted for terrestrial and for space purposes.

During the past 10 years, the main part of CELSS studies has concerned the exploration of limits of plant productivity. Very high yields were obtained in continuous and high lighting, without reaching any limit. Concepts of mineral nutrition were renewed. CELSS activities now induce a development in the techniques of image processing applied to plants in order to follow the growth, to detect stresses or diseases or to pilot harvesting robots. Notable efforts concern the development of sensors, the study of trace contaminants and the micro-organisms monitoring. In parallel, several instruments for plant culture in closed Systems were developed. The advantages of closure are emphasised in comparison with open flow systems. The concept of Artificial Ecosystems developed for space research is more and more taken into account by the scientific community. It is considered as a new tool to study basic and applied problems related to ecology and not especially concerned with space research.